| Accelerated neurodegeneration through chaperone-mediated oligomerization of tau LJ Blair, BA Nordhues, SE Hill, KM Scaglione, JC O’Leary, SN Fontaine, ... The Journal of clinical investigation 123 (10), 4158-4169, 2013 | 307 | 2013 |
| LPS-induced inflammation exacerbates phospho-tau pathology in rTg4510 mice DC Lee, J Rizer, MLB Selenica, P Reid, C Kraft, A Johnson, L Blair, ... Journal of neuroinflammation 7, 1-16, 2010 | 306 | 2010 |
| Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ... Journal of Neuroscience 33 (22), 9498-9507, 2013 | 261 | 2013 |
| The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ... Journal of Neuroscience 30 (2), 591-599, 2010 | 228 | 2010 |
| DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins SN Fontaine, D Zheng, JJ Sabbagh, MD Martin, D Chaput, A Darling, ... The EMBO journal 35 (14), 1537-1549, 2016 | 206 | 2016 |
| Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ... Molecular neurodegeneration 5, 1-11, 2010 | 201 | 2010 |
| Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy LJ Blair, HD Frauen, B Zhang, BA Nordhues, S Bijan, YC Lin, F Zamudio, ... Acta neuropathologica communications 3, 1-22, 2015 | 169 | 2015 |
| Chaperone signalling complexes in Alzheimer's disease J Koren III, UK Jinwal, DC Lee, JR Jones, CL Shults, AG Johnson, ... Journal of cellular and molecular medicine 13 (4), 619-630, 2009 | 145 | 2009 |
| Small heat shock proteins, big impact on protein aggregation in neurodegenerative disease JM Webster, AL Darling, VN Uversky, LJ Blair Frontiers in pharmacology 10, 462446, 2019 | 134 | 2019 |
| A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51 JC O'Leary III, S Dharia, LJ Blair, S Brady, AG Johnson, M Peters, ... PloS one 6 (9), e24840, 2011 | 134 | 2011 |
| Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ... Journal of Neuroscience 30 (46), 15374-15382, 2010 | 133 | 2010 |
| Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau J Abisambra, UK Jinwal, Y Miyata, J Rogers, L Blair, X Li, SP Seguin, ... Biological psychiatry 74 (5), 367-374, 2013 | 125 | 2013 |
| Imbalance of Hsp70 family variants fosters tau accumulation UK Jinwal, E Akoury, JF Abisambra, JC O'Leary III, AD Thompson, LJ Blair, ... The FASEB Journal 27 (4), 1450, 2013 | 122 | 2013 |
| Hsp90 and FKBP51: complex regulators of psychiatric diseases M Criado-Marrero, T Rein, EB Binder, JT Porter, J Koren III, LJ Blair Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 121 | 2018 |
| Targeting Hsp90 and its co-chaperones to treat Alzheimer’s disease LJ Blair, JJ Sabbagh, CA Dickey Expert opinion on therapeutic targets 18 (10), 1219-1232, 2014 | 112 | 2014 |
| Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency JJ Sabbagh, JC O'Leary III, LJ Blair, T Klengel, BA Nordhues, ... PloS one 9 (9), e107241, 2014 | 111 | 2014 |
| The emerging role of peptidyl‐prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease LJ Blair, JD Baker, JJ Sabbagh, CA Dickey Journal of neurochemistry 133 (1), 1-13, 2015 | 109 | 2015 |
| Hsp90 activator Aha1 drives production of pathological tau aggregates LB Shelton, JD Baker, D Zheng, LE Sullivan, PK Solanki, JM Webster, ... Proceedings of the National Academy of Sciences 114 (36), 9707-9712, 2017 | 107 | 2017 |
| Hsc70 rapidly engages tau after microtubule destabilization UK Jinwal, JC O'Leary, SI Borysov, JR Jones, Q Li, J Koren, JF Abisambra, ... Journal of biological chemistry 285 (22), 16798-16805, 2010 | 102 | 2010 |
| Facilitating Akt clearance via manipulation of Hsp70 activity and levels J Koren, UK Jinwal, Y Jin, J O’Leary, JR Jones, AG Johnson, LJ Blair, ... Journal of biological chemistry 285 (4), 2498-2505, 2010 | 98 | 2010 |
