Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 9502* | 2016 |
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ... N Engl j Med 366, 883-892, 2012 | 6500 | 2012 |
The causes and consequences of genetic heterogeneity in cancer evolution RA Burrell, N McGranahan, J Bartek, C Swanton Nature 501 (7467), 338-345, 2013 | 1699 | 2013 |
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ... Science 351 (6280), 1463-1469, 2016 | 1636 | 2016 |
Tracking the evolution of non–small-cell lung cancer M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ... New England Journal of Medicine 376 (22), 2109-2121, 2017 | 1079 | 2017 |
Clonal heterogeneity and tumor evolution: past, present, and the future N McGranahan, C Swanton Cell 168 (4), 613-628, 2017 | 1048 | 2017 |
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing M Gerlinger, S Horswell, J Larkin, AJ Rowan, MP Salm, I Varela, R Fisher, ... Nature genetics 46 (3), 225, 2014 | 1002 | 2014 |
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution EC de Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ... Science 346 (6206), 251-256, 2014 | 855 | 2014 |
Genetic prognostic and predictive markers in colorectal cancer A Walther, E Johnstone, C Swanton, R Midgley, I Tomlinson, D Kerr Nature Reviews Cancer 9 (7), 489-499, 2009 | 802 | 2009 |
Intratumor heterogeneity: evolution through space and time C Swanton Cancer research 72 (19), 4875-4882, 2012 | 799 | 2012 |
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution N McGranahan, C Swanton Cancer cell 27 (1), 15-26, 2015 | 752 | 2015 |
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ... Nature 545 (7655), 446-451, 2017 | 706 | 2017 |
Cancer heterogeneity: implications for targeted therapeutics R Fisher, L Pusztai, C Swanton British journal of cancer 108 (3), 479-485, 2013 | 679 | 2013 |
Renal cell carcinoma JJ Hsieh, MP Purdue, S Signoretti, C Swanton, L Albiges, M Schmidinger, ... Nature reviews Disease primers 3, 17009, 2017 | 675 | 2017 |
Replication stress links structural and numerical cancer chromosomal instability RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ... Nature 494 (7438), 492-496, 2013 | 593 | 2013 |
DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution R Rosenthal, N McGranahan, J Herrero, BS Taylor, C Swanton Genome biology 17 (1), 1-11, 2016 | 498 | 2016 |
Intratumor heterogeneity: seeing the wood for the trees TA Yap, M Gerlinger, PA Futreal, L Pusztai, C Swanton Science translational medicine 4 (127), 127ps10-127ps10, 2012 | 496 | 2012 |
Toward understanding and exploiting tumor heterogeneity AA Alizadeh, V Aranda, A Bardelli, C Blanpain, C Bock, C Borowski, ... Nature medicine 21 (8), 846, 2015 | 491 | 2015 |
Clonal status of actionable driver events and the timing of mutational processes in cancer evolution N McGranahan, F Favero, EC de Bruin, NJ Birkbak, Z Szallasi, C Swanton Science translational medicine 7 (283), 283ra54-283ra54, 2015 | 422 | 2015 |
How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine M Gerlinger, C Swanton British journal of cancer 103 (8), 1139-1143, 2010 | 420 | 2010 |