Charles Swanton
Charles Swanton
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Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ...
N Engl j Med 366, 883-892, 2012
The causes and consequences of genetic heterogeneity in cancer evolution
RA Burrell, N McGranahan, J Bartek, C Swanton
Nature 501 (7467), 338-345, 2013
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ...
Science 351 (6280), 1463-1469, 2016
Tracking the evolution of non–small-cell lung cancer
M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...
New England Journal of Medicine 376 (22), 2109-2121, 2017
Clonal heterogeneity and tumor evolution: past, present, and the future
N McGranahan, C Swanton
Cell 168 (4), 613-628, 2017
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
M Gerlinger, S Horswell, J Larkin, AJ Rowan, MP Salm, I Varela, R Fisher, ...
Nature genetics 46 (3), 225, 2014
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
EC de Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ...
Science 346 (6206), 251-256, 2014
Genetic prognostic and predictive markers in colorectal cancer
A Walther, E Johnstone, C Swanton, R Midgley, I Tomlinson, D Kerr
Nature Reviews Cancer 9 (7), 489-499, 2009
Intratumor heterogeneity: evolution through space and time
C Swanton
Cancer research 72 (19), 4875-4882, 2012
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution
N McGranahan, C Swanton
Cancer cell 27 (1), 15-26, 2015
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446-451, 2017
Cancer heterogeneity: implications for targeted therapeutics
R Fisher, L Pusztai, C Swanton
British journal of cancer 108 (3), 479-485, 2013
Renal cell carcinoma
JJ Hsieh, MP Purdue, S Signoretti, C Swanton, L Albiges, M Schmidinger, ...
Nature reviews Disease primers 3, 17009, 2017
Replication stress links structural and numerical cancer chromosomal instability
RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ...
Nature 494 (7438), 492-496, 2013
DeconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution
R Rosenthal, N McGranahan, J Herrero, BS Taylor, C Swanton
Genome biology 17 (1), 1-11, 2016
Intratumor heterogeneity: seeing the wood for the trees
TA Yap, M Gerlinger, PA Futreal, L Pusztai, C Swanton
Science translational medicine 4 (127), 127ps10-127ps10, 2012
Toward understanding and exploiting tumor heterogeneity
AA Alizadeh, V Aranda, A Bardelli, C Blanpain, C Bock, C Borowski, ...
Nature medicine 21 (8), 846, 2015
Clonal status of actionable driver events and the timing of mutational processes in cancer evolution
N McGranahan, F Favero, EC de Bruin, NJ Birkbak, Z Szallasi, C Swanton
Science translational medicine 7 (283), 283ra54-283ra54, 2015
How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine
M Gerlinger, C Swanton
British journal of cancer 103 (8), 1139-1143, 2010
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