Extremolytes: natural compounds from extremophiles for versatile applications G Lentzen, T Schwarz Applied microbiology and biotechnology 72, 623-634, 2006 | 404 | 2006 |
The Escherichia coli SRP and SecB targeting pathways converge at the translocon QA Valent, PA Scotti, S High, JWL de Gier, G Von Heijne, G Lentzen, ... The EMBO journal, 1998 | 378 | 1998 |
A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581T K Schwibbert, A Marin‐Sanguino, I Bagyan, G Heidrich, G Lentzen, ... Environmental microbiology 13 (8), 1973-1994, 2011 | 288 | 2011 |
Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer’s β-amyloid M Kanapathipillai, G Lentzen, M Sierks, CB Park FEBS letters 579 (21), 4775-4780, 2005 | 183 | 2005 |
Industrial production of the cell protectant ectoine: protection mechanisms, processes, and products H Jorg Kunte, G Lentzen, E A Galinski Current Biotechnology 3 (1), 10-25, 2014 | 171 | 2014 |
Rational design of inhibitors of HIV-1 TAR RNA through the stabilisation of electrostatic “hot spots” B Davis, M Afshar, G Varani, AIH Murchie, J Karn, G Lentzen, M Drysdale, ... Journal of molecular biology 336 (2), 343-356, 2004 | 167 | 2004 |
The effect of compatible solute ectoines on the structural organization of lipid monolayer and bilayer membranes RK Harishchandra, S Wulff, G Lentzen, T Neuhaus, HJ Galla Biophysical chemistry 150 (1-3), 37-46, 2010 | 142 | 2010 |
Structural basis for contrasting activities of ribosome binding thiazole antibiotics G Lentzen, R Klinck, N Matassova, F Aboul-ela, AIH Murchie Chemistry & Biology 10 (8), 769-778, 2003 | 127 | 2003 |
The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallography RJM Russell, JB Murray, G Lentzen, J Haddad, S Mobashery Journal of the American Chemical Society 125 (12), 3410-3411, 2003 | 101 | 2003 |
Important role of the tetraloop region of 4.5 S RNA in SRP binding to its receptor FtsY JR JAGATH, NB Matassova, E DE LEEUW, JM WARNECKE, G LENTZEN, ... Rna 7 (2), 293-301, 2001 | 81 | 2001 |
Novel effects of ectoine, a bacteria-derived natural tetrahydropyrimidine, in experimental colitis H Abdel-Aziz, W Wadie, DM Abdallah, G Lentzen, MT Khayyal Phytomedicine 20 (7), 585-591, 2013 | 78 | 2013 |
Interaction of Guanine Nucleotides with the Signal Recognition Particle from Escherichia coli JR Jagath, MV Rodnina, G Lentzen, W Wintermeyer Biochemistry 37 (44), 15408-15413, 1998 | 76 | 1998 |
Inhibition of β-amyloid peptide aggregation and neurotoxicity by α-d-mannosylglycerate, a natural extremolyte J Ryu, M Kanapathipillai, G Lentzen, CB Park peptides 29 (4), 578-584, 2008 | 68 | 2008 |
Structure of 4.5 S RNA in the signal recognition particle of Escherichia coli as studied by enzymatic and chemical probing. G Lentzen, H Moine, C Ehresmann, B Ehresmann, W Wintermeyer Rna 2 (3), 244-253, 1996 | 67 | 1996 |
The functioning of the SRP receptor FtsY in protein-targeting in E. coli is correlated with its ability to bind and hydrolyse GTP R Kusters, G Lentzen, E Eppens, A van Geel, CC van der Weijden, ... FEBS letters 372 (2-3), 253-258, 1995 | 61 | 1995 |
Compatible solutes: ectoine and hydroxyectoine improve functional nanostructures in artificial lung surfactants RK Harishchandra, AK Sachan, A Kerth, G Lentzen, T Neuhaus, HJ Galla Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (12), 2830-2840, 2011 | 59 | 2011 |
Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping CM Richardson, CL Nunns, DS Williamson, MJ Parratt, P Dokurno, ... Bioorganic & Medicinal Chemistry Letters 17 (14), 3880-3885, 2007 | 57 | 2007 |
Structure-based design of agents targeting the bacterial ribosome J Bower, M Drysdale, R Hebdon, A Jordan, G Lentzen, N Matassova, ... Bioorganic & medicinal chemistry letters 13 (15), 2455-2458, 2003 | 45 | 2003 |
Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site JB Murray, SO Meroueh, RJM Russell, G Lentzen, J Haddad, ... Chemistry & biology 13 (2), 129-138, 2006 | 44 | 2006 |
Methods and kits for discovery of RNA-binding antimicrobials J Karn, DJC Knowles, AIH Murchie, GF Lentzen US Patent 6,316,194, 2001 | 39 | 2001 |