| Mitragynine/corynantheidine pseudoindoxyls as opioid analgesics with mu agonism and delta antagonism, which do not recruit β-arrestin-2 A Váradi, GF Marrone, TC Palmer, A Narayan, MR Szabó, V Le Rouzic, ... Journal of medicinal chemistry 59 (18), 8381-8397, 2016 | 297 | 2016 |
| Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects S Majumdar, S Grinnell, V Le Rouzic, M Burgman, L Polikar, M Ansonoff, ... Proceedings of the National Academy of Sciences 108 (49), 19778-19783, 2011 | 161 | 2011 |
| 7-Hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects AC Kruegel, R Uprety, SG Grinnell, C Langreck, EA Pekarskaya, ... ACS central science 5 (6), 992-1001, 2019 | 156 | 2019 |
| The behavioral effects of the antidepressant tianeptine require the mu-opioid receptor BA Samuels, KM Nautiyal, AC Kruegel, MR Levinstein, VM Magalong, ... Neuropsychopharmacology 42 (10), 2052-2063, 2017 | 107 | 2017 |
| Regional heterogeneity of D2-receptor signaling in the dorsal striatum and nucleus accumbens PF Marcott, S Gong, P Donthamsetti, SG Grinnell, MN Nelson, ... Neuron 98 (3), 575-587. e4, 2018 | 63 | 2018 |
| Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants S Majumdar, J Subrath, V Le Rouzic, L Polikar, M Burgman, K Nagakura, ... Journal of medicinal chemistry 55 (14), 6352-6362, 2012 | 60 | 2012 |
| Generation of novel radiolabeled opiates through site-selective iodination S Majumdar, M Burgman, N Haselton, S Grinnell, J Ocampo, ... Bioorganic & medicinal chemistry letters 21 (13), 4001-4004, 2011 | 57 | 2011 |
| Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site R Uprety, T Che, SA Zaidi, SG Grinnell, BR Varga, A Faouzi, ST Slocum, ... Elife 10, e56519, 2021 | 48 | 2021 |
| Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants SG Grinnell, M Ansonoff, GF Marrone, Z Lu, A Narayan, J Xu, G Rossi, ... Synapse 70 (10), 395-407, 2016 | 45 | 2016 |
| Pharmacologic characterization in the rat of a potent analgesic lacking respiratory depression, IBNtxA SG Grinnell, S Majumdar, A Narayan, V Le Rouzic, M Ansonoff, JE Pintar, ... Journal of Pharmacology and Experimental Therapeutics 350 (3), 710-718, 2014 | 35 | 2014 |
| Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS GF Marrone, SG Grinnell, Z Lu, GC Rossi, V Le Rouzic, J Xu, S Majumdar, ... Proceedings of the National Academy of Sciences 113 (13), 3663-3668, 2016 | 29 | 2016 |
| Mild, Pd-catalyzed stannylation of radioiodination targets JE Pickett, A Váradi, TC Palmer, SG Grinnell, JM Schrock, GW Pasternak, ... Bioorganic & medicinal chemistry letters 25 (8), 1761-1764, 2015 | 25 | 2015 |
| Novel 6β-acylaminomorphinans with analgesic activity A Váradi, S Hosztafi, V Le Rouzic, G Tóth, Á Urai, B Noszál, ... European journal of medicinal chemistry 69, 786-789, 2013 | 22 | 2013 |
| Mu opioid receptors on hippocampal GABAergic interneurons are critical for the antidepressant effects of tianeptine J Han, V Andreu, C Langreck, EA Pekarskaya, SG Grinnell, F Allain, ... Neuropsychopharmacology 47 (7), 1387-1397, 2022 | 15 | 2022 |
| Sandmeyer reaction repurposed for the site-selective, non-oxidizing radioiodination of fully-deprotected peptides: studies on the endogenous opioid peptide α-neoendorphin JE Pickett, K Nagakura, AR Pasternak, SG Grinnell, S Majumdar, ... Bioorganic & medicinal chemistry letters 23 (15), 4347-4350, 2013 | 11 | 2013 |
| Synthesis and characterization of azido aryl analogs of IBNtxA for Radio-photoaffinity labeling opioid receptors in cell lines and in mouse brain SG Grinnell, R Uprety, A Varadi, J Subrath, A Hunkele, YX Pan, ... Cellular and molecular neurobiology 41 (5), 977-993, 2021 | 9 | 2021 |
| Extreme vetting of dopamine receptor oligomerization WB Asher, S Mathiasen, MD Holsey, SG Grinnell, NA Lambert, JA Javitch G-Protein-Coupled Receptor Dimers, 99-127, 2017 | 8 | 2017 |
| V; Burgman, M.; Polikar, L.; Ansonoff, M.; Pintar S Majumdar, S Grinnell, R Le J. PAN, YX PASTERNAK, G. W:" Truncated G protein-coupled mu opioid receptor …, 2011 | 6 | 2011 |
| Targeting truncated G‐protein coupled opioid receptors for treatment of pain without side‐effects S Majumdar, SG Grinnell, M Burgman, L Polikar, V Le Rouzic, M Ansonoff, ... The FASEB Journal 25, 618.8-618.8, 2011 | 1 | 2011 |
| The Antidepressant Actions of Tianeptine Require the Mu-Opioid Receptor K Nautiyal, B Samuels, A Kruegel, M Levinstein, V Magalong, ... NEUROPSYCHOPHARMACOLOGY 41, S149-S149, 2016 | | 2016 |
