| Modeling Alzheimer’s disease with iPSC-derived brain cells J Penney, WT Ralvenius, LH Tsai Molecular psychiatry 25 (1), 148-167, 2020 | 367 | 2020 |
| Targeted ablation, silencing, and activation establish glycinergic dorsal horn neurons as key components of a spinal gate for pain and itch E Foster, H Wildner, L Tudeau, S Haueter, WT Ralvenius, M Jegen, ... Neuron 85 (6), 1289-1304, 2015 | 366 | 2015 |
| APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia G Sienski, P Narayan, JM Bonner, N Kory, S Boland, AA Arczewska, ... Science translational medicine 13 (583), eaaz4564, 2021 | 190 | 2021 |
| APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes JW Blanchard, LA Akay, J Davila-Velderrain, D von Maydell, H Mathys, ... Nature 611 (7937), 769-779, 2022 | 167 | 2022 |
| Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype WT Ralvenius, D Benke, MA Acuna, U Rudolph, HU Zeilhofer Nature communications 6 (1), 6803, 2015 | 118 | 2015 |
| Acetaminophen relieves inflammatory pain through CB1 cannabinoid receptors in the rostral ventromedial medulla PP Klinger-Gratz, WT Ralvenius, E Neumann, A Kato, R Nyilas, Z Lele, ... Journal of Neuroscience 38 (2), 322-334, 2018 | 79 | 2018 |
| Antihyperalgesia by α2-GABAA receptors occurs via a genuine spinal action and does not involve supraspinal sites J Paul, GE Yévenes, D Benke, AD Lio, WT Ralvenius, R Witschi, ... Neuropsychopharmacology 39 (2), 477-487, 2014 | 60 | 2014 |
| Phosphorylation state–dependent modulation of spinal glycine receptors alleviates inflammatory pain MA Acuña, GE Yévenes, WT Ralvenius, D Benke, A Di Lio, CO Lara, ... The Journal of clinical investigation 126 (7), 2547-2560, 2016 | 59 | 2016 |
| Restoring the spinal pain gate: GABAA receptors as targets for novel analgesics HU Zeilhofer, WT Ralvenius, MA Acuña Advances in pharmacology 73, 71-96, 2015 | 57 | 2015 |
| Localization and production of peptide endocannabinoids in the rodent CNS and adrenal medulla SC Hofer, WT Ralvenius, MS Gachet, JM Fritschy, HU Zeilhofer, J Gertsch Neuropharmacology 98, 78-89, 2015 | 53 | 2015 |
| A virus-like particle-based anti-nerve growth factor vaccine reduces inflammatory hyperalgesia: potential long-term therapy for chronic pain TA Röhn, WT Ralvenius, J Paul, P Borter, M Hernandez, R Witschi, ... The Journal of Immunology 186 (3), 1769-1780, 2011 | 35 | 2011 |
| Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors WT Ralvenius, E Neumann, M Pagani, MA Acuña, H Wildner, D Benke, ... Nature communications 9 (1), 1-15, 2018 | 32 | 2018 |
| The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia WT Ralvenius, MA Acuna, D Benke, A Matthey, Y Daali, U Rudolph, ... Neuropharmacology 109, 366-375, 2016 | 30 | 2016 |
| GABAA receptor subtypes in the mouse brain: regional mapping and diazepam receptor occupancy by in vivo [18F] flumazenil PET AM Herde, D Benke, WT Ralvenius, L Mu, R Schibli, HU Zeilhofer, ... Neuroimage 150, 279-291, 2017 | 23 | 2017 |
| Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration N Morshed, WT Ralvenius, A Nott, LA Watson, FH Rodriguez, LA Akay, ... Molecular Systems Biology 16 (12), e9819, 2020 | 22 | 2020 |
| The positive allosteric GABAB receptor modulator rac-BHFF enhances baclofen-mediated analgesia in neuropathic mice K Zemoura, WT Ralvenius, P Malherbe, D Benke Neuropharmacology 108, 172-178, 2016 | 17 | 2016 |
| Hö sli, L E Foster, H Wildner, L Tudeau, S Haueter, WT Ralvenius, M Jegen, ... Haenraets, K., Ghanem, A., et al, 1289-1304, 2015 | 13 | 2015 |
| APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia. Sci Transl Med 13 G Sienski, P Narayan, JM Bonner, N Kory, S Boland, AA Arczewska, ... | 10 | 2021 |
| TP003 is a non-selective benzodiazepine site agonist that induces anxiolysis via α2GABAA receptors E Neumann, WT Ralvenius, MA Acuña, U Rudolph, HU Zeilhofer Neuropharmacology 143, 71-78, 2018 | 9 | 2018 |
| Mice lacking spinal α2GABAA receptors: Altered GABAergic neurotransmission, diminished GABAergic antihyperalgesia, and potential compensatory mechanisms preventing a … L Tudeau, MA Acuña, GW Albisetti, E Neumann, WT Ralvenius, ... Brain research 1741, 146889, 2020 | 6 | 2020 |
