Követés
Lars Weidolf
Lars Weidolf
Ismeretlen szervezet
E-mail megerősítve itt: astrazeneca.com
Cím
Hivatkozott rá
Hivatkozott rá
Év
Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities
XQ Li, TB Andersson, M Ahlström, L Weidolf
Drug metabolism and disposition 32 (8), 821-827, 2004
8662004
Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes
A Äbelö, TB Andersson, M Antonsson, AK Naudot, I Skånberg, L Weidolf
Drug Metabolism and Disposition 28 (8), 966-972, 2000
4492000
Pharmacokinetic studies with esomeprazole, the (S)-isomer of omeprazole
T Andersson, M Hassan-Alin, G Hasselgren, K Röhss, L Weidolf
Clinical pharmacokinetics 40 (6), 411-426, 2001
3062001
Comparison between electrochemistry/mass spectrometry and cytochrome P450 catalyzed oxidation reactions
U Jurva, HV Wikström, L Weidolf, AP Bruins
Rapid communications in mass spectrometry 17 (8), 800-810, 2003
2162003
In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs
RA Thompson, EM Isin, Y Li, L Weidolf, K Page, I Wilson, S Swallow, ...
Chemical research in toxicology 25 (8), 1616-1632, 2012
2062012
Use of radiolabeled compounds in drug metabolism and pharmacokinetic studies
EM Isin, CS Elmore, GN Nilsson, RA Thompson, L Weidolf
Chemical research in toxicology 25 (3), 532-542, 2012
1972012
Determination of sulfonated azo dyes by liquid chromatography/atmospheric pressure ionization mass spectrometry
AP Bruins, LOG Weidolf, JD Henion, WL Budde
Analytical Chemistry 59 (22), 2647-2652, 1987
1581987
Mimicry of phase I drug metabolism–novel methods for metabolite characterization and synthesis
T Johansson, L Weidolf, U Jurva
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2007
1442007
State-of-the-art tools for computational site of metabolism predictions: comparative analysis, mechanistical insights, and future applications
L Afzelius, C Hasselgren Arnby, A Broo, L Carlsson, C Isaksson, U Jurva, ...
Drug metabolism reviews 39 (1), 61-86, 2007
1432007
Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole
P Lindberg, L Weidolf
US Patent 5,877,192, 1999
1281999
Determination of boldenone sulfoconjugate and related steroid sulfates in equine urine by high‐performance liquid chromatography/tandem mass spectrometry
LOG Weidolf, ED Lee, JD Henion
Biomedical & environmental mass spectrometry 15 (5), 283-289, 1988
1191988
Stereoselective disposition of proton pump inhibitors
T Andersson, L Weidolf
Clinical Drug Investigation 28 (5), 263-279, 2008
1002008
Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development
RA Thompson, EM Isin, Y Li, R Weaver, L Weidolf, I Wilson, A Claesson, ...
Chemico-biological interactions 192 (1-2), 65-71, 2011
892011
Cytochrome P450-mediated activation of the fragrance compound geraniol forms potent contact allergens
L Hagvall, JM Baron, A Börje, L Weidolf, H Merk, AT Karlberg
Toxicology and applied pharmacology 233 (2), 308-313, 2008
792008
In vitro metabolism of haloperidol and sila-haloperidol: new metabolic pathways resulting from carbon/silicon exchange
T Johansson, L Weidolf, F Popp, R Tacke, U Jurva
Drug metabolism and disposition 38 (1), 73-83, 2010
762010
In vitro evaluation of major in vivo drug metabolic pathways using primary human hepatocytes and HepaRG cells in suspension and a dynamic three-dimensional bioreactor system
M Darnell, M Ulvestad, E Ellis, L Weidolf, TB Andersson
Journal of Pharmacology and Experimental Therapeutics 343 (1), 134-144, 2012
702012
Novel metabolites of amodiaquine formed by CYP1A1 and CYP1B1: structure elucidation using electrochemistry, mass spectrometry, and NMR
T Johansson, U Jurva, G Grönberg, L Weidolf, C Masimirembwa
Drug metabolism and disposition 37 (3), 571-579, 2009
692009
Stereoselective metabolism by human liver CYP enzymes of a substituted benzimidazole
A Äbelö, TB Andersson, ULF Bredberg, I Skånberg, L Weidolf
Drug metabolism and disposition 28 (1), 58-64, 2000
672000
Electrochemical generation of electrophilic drug metabolites: characterization of amodiaquine quinoneimine and cysteinyl conjugates by MS, IR, and NMR
U Jurva, A Holmén, G Grönberg, C Masimirembwa, L Weidolf
Chemical research in toxicology 21 (4), 928-935, 2008
602008
Metabolism of xenobiotic carboxylic acids: focus on coenzyme A conjugation, reactivity, and interference with lipid metabolism
M Darnell, L Weidolf
Chemical research in toxicology 26 (8), 1139-1155, 2013
572013
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