Követés
Diego Muñoz-Torrero
Diego Muñoz-Torrero
Associate Professor, Faculty of Pharmacy and Food Sciences, University of Barcelona
E-mail megerősítve itt: ub.edu
Cím
Hivatkozott rá
Hivatkozott rá
Év
Acetylcholinesterase inhibitors as disease-modifying therapies for Alzheimer's disease
D Munoz-Torrero
Current medicinal chemistry 15 (24), 2433-2455, 2008
2872008
New tacrine− huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease
P Camps, R El Achab, J Morral, D Muñoz-Torrero, A Badia, JE Baños, ...
Journal of medicinal chemistry 43 (24), 4657-4666, 2000
2402000
Novel donepezil-based inhibitors of acetyl-and butyrylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation
P Camps, X Formosa, C Galdeano, T Gómez, D Munoz-Torrero, ...
Journal of medicinal chemistry 51 (12), 3588-3598, 2008
2172008
Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds
P Camps, X Formosa, C Galdeano, D Munoz-Torrero, L Ramírez, ...
Journal of medicinal chemistry 52 (17), 5365-5379, 2009
2132009
3D Structure of Torpedo californica Acetylcholinesterase Complexed with Huprine X at 2.1 Å Resolution:  Kinetic and Molecular Dynamic Correlates,
H Dvir, DM Wong, M Harel, X Barril, M Orozco, FJ Luque, ...
Biochemistry 41 (9), 2970-2981, 2002
1642002
Synthesis, in Vitro Pharmacology, and Molecular Modeling of Very Potent Tacrine− Huperzine A Hybrids as Acetylcholinesterase Inhibitors of Potential Interest for the Treatment …
P Camps, R El Achab, DM Görbig, J Morral, D Muñoz-Torrero, A Badia, ...
Journal of medicinal chemistry 42 (17), 3227-3242, 1999
1631999
Huprine X is a novel high-affinity inhibitor of acetylcholinesterase that is of interest for treatment of Alzheimer's disease
P Camps, B Cusack, WD Mallender, R El Achab, J Morral, ...
Molecular pharmacology 57 (2), 409-417, 2000
1512000
Dimeric and hybrid anti-Alzheimer drug candidates
D Munoz-Torrero, P Camps
Current medicinal chemistry 13 (4), 399-422, 2006
1372006
Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents
E Viayna, I Sola, M Bartolini, A De Simone, C Tapia-Rojas, FG Serrano, ...
Journal of Medicinal Chemistry 57 (6), 2549-2567, 2014
1292014
Cholinergic drugs in pharmacotherapy of Alzheimer's disease
P Camps, D Munoz-Torrero
Mini Reviews in Medicinal Chemistry 2 (1), 11-25, 2002
1162002
Cholinergic drugs in pharmacotherapy of Alzheimer's disease
P Camps, D Munoz-Torrero
Mini Reviews in Medicinal Chemistry 2 (1), 11-25, 2002
1162002
Synthesis and evaluation of tacrine–Huperzine a hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of alzheimer’s disease
A Badia, JE Baños, P Camps, J Contreras, DM Görbig, D Muñoz-Torrero, ...
Bioorganic & medicinal chemistry 6 (4), 427-440, 1998
1081998
Huprine–tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer’s and prion diseases
C Galdeano, E Viayna, I Sola, X Formosa, P Camps, A Badia, MV Clos, ...
Journal of medicinal chemistry 55 (2), 661-669, 2012
1022012
Synthesis and pharmacological evaluation of huprine− tacrine heterodimers: Subnanomolar dual Binding site acetylcholinesterase inhibitors
P Camps, X Formosa, D Muñoz-Torrero, J Petrignet, A Badia, MV Clos
Journal of medicinal chemistry 48 (6), 1701-1704, 2005
1012005
Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates
P Camps, X Formosa, C Galdeano, T Gómez, D Muñoz-Torrero, ...
Chemico-biological interactions 187 (1-3), 411-415, 2010
962010
Dual inhibitors of β-amyloid aggregation and acetylcholinesterase as multi-target anti-Alzheimer drug candidates
E Viayna, R Sabate, D Muñoz-Torrero
Current topics in medicinal chemistry 13 (15), 1820-1842, 2013
862013
Novel Huprine Derivatives with Inhibitory Activity toward β‐Amyloid Aggregation and Formation as Disease‐Modifying Anti‐Alzheimer Drug Candidates
E Viayna, T Gómez, C Galdeano, L Ramírez, M Ratia, A Badia, MV Clos, ...
ChemMedChem 5 (11), 1855-1870, 2010
722010
Polycyclic aminopyridine compounds which are acetylcholinesterase inhibitors, process for preparing them and their use
PC Garcia, DMT Lopez-Ibarra, DMG Romeu, JC Lascorz, MS Fornell, ...
US Patent 5,965,569, 1999
671999
Combined in vitro cell-based/in silico screening of naturally occurring flavonoids and phenolic compounds as potential anti-Alzheimer drugs
A Espargaró, T Ginex, MM Vadell, MA Busquets, J Estelrich, ...
Journal of natural products 80 (2), 278-289, 2017
642017
Synthesis, in vitro pharmacology, and molecular modeling of syn-huprines as acetylcholinesterase inhibitors
P Camps, E Gómez, D Muñoz-Torrero, A Badia, NM Vivas, X Barril, ...
Journal of medicinal chemistry 44 (26), 4733-4736, 2001
622001
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