Enzyme-activatable polymer–drug conjugate augments tumour penetration and treatment efficacy Q Zhou, S Shao, J Wang, C Xu, J Xiang, Y Piao, Z Zhou, Q Yu, J Tang, ... Nature nanotechnology 14 (8), 799-809, 2019 | 576 | 2019 |
Nonviral cancer gene therapy: Delivery cascade and vector nanoproperty integration Z Zhou, X Liu, D Zhu, Y Wang, Z Zhang, X Zhou, N Qiu, X Chen, Y Shen Advanced drug delivery reviews 115, 115-154, 2017 | 339 | 2017 |
Fusogenic reactive oxygen species triggered charge‐reversal vector for effective gene delivery X Liu, J Xiang, D Zhu, L Jiang, Z Zhou, J Tang, X Liu, Y Huang, Y Shen Advanced Materials 28 (9), 1743-1752, 2016 | 313 | 2016 |
A tumor‐specific cascade amplification drug release nanoparticle for overcoming multidrug resistance in cancers M Ye, Y Han, J Tang, Y Piao, X Liu, Z Zhou, J Gao, J Rao, Y Shen Advanced Materials 29 (38), 1702342, 2017 | 300 | 2017 |
Small molecule induced reactivation of mutant p53 in cancer cells X Liu, R Wilcken, AC Joerger, IS Chuckowree, J Amin, J Spencer, ... Nucleic acids research 41 (12), 6034-6044, 2013 | 243 | 2013 |
Halogen-enriched fragment libraries as leads for drug rescue of mutant p53 R Wilcken, X Liu, MO Zimmermann, TJ Rutherford, AR Fersht, AC Joerger, ... Journal of the American Chemical Society 134 (15), 6810-6818, 2012 | 243 | 2012 |
Esterase‐activated charge‐reversal polymer for fibroblast‐exempt cancer gene therapy N Qiu, X Liu, Y Zhong, Z Zhou, Y Piao, L Miao, Q Zhang, J Tang, L Huang, ... Advanced Materials 28 (48), 10613-10622, 2016 | 194 | 2016 |
Substituted 4-(thiazol-5-yl)-2-(phenylamino) pyrimidines are highly active CDK9 inhibitors: synthesis, X-ray crystal structures, structure–activity relationship, and anticancer … H Shao, S Shi, S Huang, AJ Hole, AY Abbas, S Baumli, X Liu, F Lam, ... Journal of medicinal chemistry 56 (3), 640-659, 2013 | 133 | 2013 |
Synthesis and biological evaluation of imidazo [4, 5-b] pyridine and 4-heteroaryl-pyrimidine derivatives as anti-cancer agents PM Lukasik, S Elabar, F Lam, H Shao, X Liu, AY Abbas, S Wang European journal of medicinal chemistry 57, 311-322, 2012 | 103 | 2012 |
Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity J Liang, H Wang, W Ding, J Huang, X Zhou, H Wang, X Dong, G Li, ... Science advances 6 (35), eabc3646, 2020 | 95 | 2020 |
Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases T Wan, J Zhong, Q Pan, T Zhou, Y Ping, X Liu Science advances 8 (37), eabp9435, 2022 | 91 | 2022 |
Macrophage‐mediated tumor cell phagocytosis: opportunity for nanomedicine intervention X Zhou, X Liu, L Huang Advanced functional materials 31 (5), 2006220, 2021 | 87 | 2021 |
Intracellularly disintegratable polysulfoniums for efficient gene delivery D Zhu, H Yan, X Liu, J Xiang, Z Zhou, J Tang, X Liu, Y Shen Advanced Functional Materials 27 (16), 1606826, 2017 | 86 | 2017 |
A non-cytotoxic dendrimer with innate and potent anticancer and anti-metastatic activities S Shao, Q Zhou, J Si, J Tang, X Liu, M Wang, J Gao, K Wang, R Xu, ... Nature Biomedical Engineering 1 (9), 745-757, 2017 | 82 | 2017 |
Progress and perspective of microneedle system for anti-cancer drug delivery D Li, D Hu, H Xu, HK Patra, X Liu, Z Zhou, J Tang, N Slater, Y Shen Biomaterials 264, 120410, 2021 | 78 | 2021 |
Amphiphilic drugs as surfactants to fabricate excipient-free stable nanodispersions of hydrophobic drugs for cancer chemotherapy S Hu, E Lee, C Wang, J Wang, Z Zhou, Y Li, X Li, J Tang, DH Lee, X Liu, ... Journal of Controlled Release 220, 175-179, 2015 | 77 | 2015 |
Assemblies of peptide‐cytotoxin conjugates for tumor‐homing chemotherapy J Wang, S Hu, W Mao, J Xiang, Z Zhou, X Liu, J Tang, Y Shen Advanced Functional Materials 29 (7), 1807446, 2019 | 71 | 2019 |
CDKI‐71, a novel CDK9 inhibitor, is preferentially cytotoxic to cancer cells compared to flavopiridol X Liu, S Shi, F Lam, C Pepper, PM Fischer, S Wang International journal of cancer 130 (5), 1216-1226, 2012 | 71 | 2012 |
Detailed investigation on how the protein corona modulates the physicochemical properties and gene delivery of polyethylenimine (PEI) polyplexes D Zhu, H Yan, Z Zhou, J Tang, X Liu, R Hartmann, WJ Parak, N Feliu, ... Biomaterials science 6 (7), 1800-1817, 2018 | 59 | 2018 |
Terminating the criminal collaboration in pancreatic cancer: nanoparticle-based synergistic therapy for overcoming fibroblast-induced drug resistance L Wang, X Liu, Q Zhou, M Sui, Z Lu, Z Zhou, J Tang, Y Miao, M Zheng, ... Biomaterials 144, 105-118, 2017 | 58 | 2017 |