Deep learning suggests that gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure J Zrimec, CS Börlin, F Buric, AS Muhammad, R Chen, V Siewers, ... Nature communications 11 (1), 6141, 2020 | 115 | 2020 |
Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy HC Affronti, AM Rowsam, AJ Pellerite, SR Rosario, MD Long, JJ Jacobi, ... Nature communications 11 (1), 52, 2020 | 45 | 2020 |
Controlling gene expression with deep generative design of regulatory DNA J Zrimec, X Fu, AS Muhammad, C Skrekas, V Jauniskis, NK Speicher, ... Nature communications 13 (1), 5099, 2022 | 41 | 2022 |
Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics CS Börlin, V Lang, A Hamacher-Brady, NR Brady Cell Communication and Signaling 12, 1-16, 2014 | 25 | 2014 |
Predictive models of eukaryotic transcriptional regulation reveals changes in transcription factor roles and promoter usage between metabolic conditions P Holland, D Bergenholm, CS Börlin, G Liu, J Nielsen Nucleic acids research 47 (10), 4986-5000, 2019 | 24 | 2019 |
Dietary folate levels alter the kinetics and molecular mechanism of prostate cancer recurrence in the CWR22 model HC Affronti, MD Long, SR Rosario, BM Gillard, E Karasik, CS Boerlin, ... Oncotarget 8 (61), 103758, 2017 | 20 | 2017 |
Saccharomyces cerevisiae displays a stable transcription start site landscape in multiple conditions CS Börlin, N Cvetesic, P Holland, D Bergenholm, V Siewers, B Lenhard, ... FEMS yeast research 19 (2), foy128, 2019 | 11 | 2019 |
Supervised generative design of regulatory DNA for gene expression control J Zrimec, X Fu, AS Muhammad, C Skrekas, V Jauniskis, NK Speicher, ... BioRxiv, 2021.07. 15.452480, 2021 | 5 | 2021 |
A bioinformatic pipeline to analyze ChIP-exo datasets CS Börlin, D Bergenholm, P Holland, J Nielsen Biology Methods and Protocols 4 (1), bpz011, 2019 | 4 | 2019 |
The transcription factor Leu3 shows differential binding behavior in response to changing leucine availability CS Börlin, J Nielsen, V Siewers FEMS Microbiology Letters 367 (13), fnaa107, 2020 | 2 | 2020 |
An analytical framework for studying transcriptional regulation CS BÖRLIN | | 2020 |
Define working culture, don't leave it to chance K Campbell, Y Dabirian, C Börlin, F Di Bartolomeo Nature 565 (7739), 294-294, 2019 | | 2019 |