Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates L Mátés, MKL Chuah, E Belay, B Jerchow, N Manoj, A Acosta-Sanchez, ... Nature genetics 41 (6), 753-761, 2009 | 1084 | 2009 |
Transposon-mediated genome manipulation in vertebrates Z Ivics, MA Li, L Mátés, JD Boeke, A Nagy, A Bradley, Z Izsvák Nature methods 6 (6), 415-422, 2009 | 368 | 2009 |
Comparative analysis of transposable element vector systems in human cells I Grabundzija, M Irgang, L Mátés, E Belay, J Matrai, A Gogol-Döring, ... Molecular therapy 18 (6), 1200-1209, 2010 | 280 | 2010 |
The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor Z Jin, S Maiti, H Huls, H Singh, S Olivares, L Mátés, Z Izsvák, Z Ivics, ... Gene therapy 18 (9), 849-856, 2011 | 147 | 2011 |
Stable gene transfer and expression in cord blood–derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system X Xue, X Huang, SE Nodland, L Mátés, L Ma, Z Izsvák, Z Ivics, TW LeBien, ... Blood, The Journal of the American Society of Hematology 114 (7), 1319-1330, 2009 | 145 | 2009 |
Germline transgenic pigs by Sleeping Beauty transposition in porcine zygotes and targeted integration in the pig genome W Garrels, L Mátés, S Holler, A Dalda, U Taylor, B Petersen, H Niemann, ... PloS one 6 (8), e23573, 2011 | 144 | 2011 |
The Ancient mariner Sails Again: Transposition of the Human Hsmar1 Element by a Reconstructed Transposase and Activities of the SETMAR Protein on … C Miskey, B Papp, L Mátés, L Sinzelle, H Keller, Z Izsvák, Z Ivics Molecular and cellular biology 27 (12), 4589-4600, 2007 | 135 | 2007 |
Hybrid lentivirus-transposon vectors with a random integration profile in human cells NH Staunstrup, B Moldt, L Mátés, P Villesen, M Jakobsen, Z Ivics, Z Izsvák, ... Molecular Therapy 17 (7), 1205-1214, 2009 | 117 | 2009 |
Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons Z Ivics, W Garrels, L Mátés, TY Yau, S Bashir, V Zidek, V Landa, A Geurts, ... Nature protocols 9 (4), 810-827, 2014 | 110 | 2014 |
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits K Katter, AM Geurts, O Hoffmann, L Mátés, V Landa, L Hiripi, C Moreno, ... The FASEB Journal 27 (3), 930, 2013 | 110 | 2013 |
Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells B Moldt, C Miskey, NH Staunstrup, A Gogol-Döring, RO Bak, N Sharma, ... Molecular Therapy 19 (8), 1499-1510, 2011 | 95 | 2011 |
Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons Z Ivics, L Mátés, TY Yau, V Landa, V Zidek, S Bashir, OI Hoffmann, L Hiripi, ... Nature protocols 9 (4), 773-793, 2014 | 78 | 2014 |
Applying a “double-feature” promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon-based gene delivery TI Orbán, Á Apáti, A Németh, N Varga, V Krizsik, A Schamberger, ... Stem cells 27 (5), 1077-1087, 2009 | 77 | 2009 |
Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives L Mátés, Z Izsvák, Z Ivics Genome biology 8, 1-19, 2007 | 77 | 2007 |
Cell division promotes efficient retrotransposition in a stable L1 reporter cell line Y Xie, L Mates, Z Ivics, Z Izsvák, SL Martin, W An Mobile DNA 4, 1-10, 2013 | 70 | 2013 |
Germline transgenesis in rabbits by pronuclear microinjection of Sleeping Beauty transposons Z Ivics, L Hiripi, OI Hoffmann, L Mátés, TY Yau, S Bashir, V Zidek, V Landa, ... Nature protocols 9 (4), 794-809, 2014 | 68 | 2014 |
Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering F Voigt, L Wiedemann, C Zuliani, I Querques, A Sebe, L Mátés, Z Izsvák, ... Nature communications 7 (1), 11126, 2016 | 66 | 2016 |
Reliable transgene-independent method for determining Sleeping Beauty transposon copy numbers O Kolacsek, V Krízsik, A Schamberger, Z Erdei, Á Apáti, G Várady, ... Mobile DNA 2, 1-8, 2011 | 64 | 2011 |
Novel hyperactive transposons for genetic modification of induced pluripotent and adult stem cells: a nonviral paradigm for coaxed differentiation E Belay, J Mátrai, A Acosta-Sanchez, L Ma, M Quattrocelli, L Mátés, ... Stem Cells 28 (10), 1760-1771, 2010 | 61 | 2010 |
Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities L Mátés, C Nicolae, M Mörgelin, F Deák, I Kiss, A Aszódi Matrix Biology 23 (3), 195-204, 2004 | 53 | 2004 |