| Targeting myosin by blebbistatin derivatives: optimization and pharmacological potential AÁ Rauscher, M Gyimesi, M Kovács, A Málnási-Csizmadia Trends in biochemical sciences 43 (9), 700-713, 2018 | 110 | 2018 |
| From keys to bulldozers: expanding roles for winged helix domains in nucleic-acid-binding proteins GM Harami, M Gyimesi, M Kovács Trends in biochemical sciences 38 (7), 364-371, 2013 | 99 | 2013 |
| Reversible movement of switch 1 loop of myosin determines actin interaction B Kintses, M Gyimesi, DS Pearson, MA Geeves, W Zeng, CR Bagshaw, ... The EMBO journal 26 (1), 265-274, 2007 | 73 | 2007 |
| The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II M Gyimesi, B Kintses, A Bodor, A Perczel, S Fischer, CR Bagshaw, ... Journal of Biological Chemistry 283 (13), 8153-8163, 2008 | 69 | 2008 |
| Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke B Takács, N Billington, M Gyimesi, B Kintses, A Málnási-Csizmadia, ... Proceedings of the National Academy of Sciences 107 (15), 6799-6804, 2010 | 63 | 2010 |
| Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA M Gyimesi, K Sarlos, M Kovacs Nucleic acids research 38 (13), 4404-4414, 2010 | 55 | 2010 |
| Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state M Špírek, J Mlčoušková, O Beláň, M Gyimesi, GM Harami, E Molnár, ... Nucleic Acids Research 46 (8), 3967-3980, 2018 | 50 | 2018 |
| Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination GM Harami, Y Seol, J In, V Ferencziová, M Martina, M Gyimesi, K Sarlós, ... Proceedings of the National Academy of Sciences 114 (4), E466-E475, 2017 | 38 | 2017 |
| RecQ helicase translocates along single-stranded DNA with a moderate processivity and tight mechanochemical coupling K Sarlós, M Gyimesi, M Kovács Proceedings of the National Academy of Sciences 109 (25), 9804-9809, 2012 | 35 | 2012 |
| Single residue variation in skeletal muscle myosin enables direct and selective drug targeting for spasticity and muscle stiffness M Gyimesi, ÁI Horváth, D Túrós, SK Suthar, M Pénzes, C Kurdi, L Canon, ... Cell 183 (2), 335-346. e13, 2020 | 34 | 2020 |
| RecQ helicase triggers a binding mode change in the SSB–DNA complex to efficiently initiate DNA unwinding M Mills, GM Harami, Y Seol, M Gyimesi, M Martina, ZJ Kovács, M Kovács, ... Nucleic acids research 45 (20), 11878-11890, 2017 | 31 | 2017 |
| Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains M Gyimesi, GM Harami, K Sarlos, E Hazai, Z Bikadi, M Kovacs Nucleic acids research 40 (9), 3952-3963, 2012 | 31 | 2012 |
| Enzyme kinetics above denaturation temperature: a temperature-jump/stopped-flow apparatus B Kintses, Z Simon, M Gyimesi, J Tóth, B Jelinek, C Niedetzky, M Kovács, ... Biophysical journal 91 (12), 4605-4610, 2006 | 26 | 2006 |
| kinetic characterization of the function of myosin loop 4 in the actin− myosin interaction M Gyimesi, AK Tsaturyan, MSZ Kellermayer, A Málnási-Csizmadia Biochemistry 47 (1), 283-291, 2008 | 25 | 2008 |
| Functional adaptation of the switch-2 nucleotide sensor enables rapid processive translocation by myosin-5. NT Nagy, T Sakamoto, B Takács, M Gyimesi, E Hazai, Z Bikádi, JR Sellers, ... The FASEB Journal 24 (11), 4480, 2010 | 22 | 2010 |
| Myosin cleft closure by double electron–electron resonance and dipolar EPR PG Fajer, M Gyimesi, A Malnasi-Csizmadia, CR Bagshaw, KI Sen, L Song Journal of Physics: Condensed Matter 19 (28), 285208, 2007 | 21 | 2007 |
| Visualization of human Bloom's syndrome helicase molecules bound to homologous recombination intermediates M Gyimesi, RH Pires, N Billington, ZS Kocsis, K Módos, MSZ Kellermayer, ... The FASEB Journal 27 (12), 4954, 2013 | 18 | 2013 |
| Streamlined determination of processive run length and mechanochemical coupling of nucleic acid motor activities M Gyimesi, K Sarlós, I Derényi, M Kovács Nucleic acids research 38 (7), e102-e102, 2010 | 18 | 2010 |
| Direct myosin-2 inhibition enhances cerebral perfusion resulting in functional improvement after ischemic stroke M Pénzes, D Túrós, D Máthé, K Szigeti, N Hegedűs, AÁ Rauscher, P Tóth, ... Theranostics 10 (12), 5341, 2020 | 14 | 2020 |
| The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom’s syndrome helicase for efficient disruption of D-loops GM Harami, J Pálinkás, Y Seol, ZJ Kovács, M Gyimesi, H Harami-Papp, ... Nature Communications 13 (1), 654, 2022 | 10 | 2022 |
Mihály KovácsEötvös Loránd University, Department of Biochemistry, Budapest, HungaryVerified email at elte.hu
