Judit E Szabó, PhD
Judit E Szabó, PhD
Richter Gedeon Nyrt.
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Role of PCNA and TLS polymerases in D-loop extension during homologous recombination in humans
M Sebesta, P Burkovics, S Juhasz, S Zhang, JE Szabo, MYWT Lee, ...
DNA repair 12 (9), 691-698, 2013
Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control
JE Szabo, V Németh, V Papp-Kádár, K Nyíri, I Leveles, AA Bendes, ...
Nucleic acids research 42 (19), 11912-11920, 2014
Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination
I Pécsi, JE Szabó, SD Adams, I Simon, JR Sellers, BG Vértessy, J Tóth
Proceedings of the National Academy of Sciences 108 (35), 14437-14442, 2011
Life without dUTPase
C Kerepesi, JE Szabó, V Papp-Kádár, O Dobay, D Szabó, V Grolmusz, ...
Frontiers in microbiology 7, 1768, 2016
Cross-species inhibition of dUTPase via the Staphylococcal Stl protein perturbs dNTP pool and colony formation in Mycobacterium
R Hirmondó, JE Szabó, K Nyíri, S Tarjányi, P Dobrotka, J Tóth, ...
DNA repair 30, 21-27, 2015
Structure and enzymatic mechanism of a moonlighting dUTPase
I Leveles, V Németh, JE Szabó, V Harmat, K Nyíri, ÁÁ Bendes, ...
Acta Crystallographica Section D: Biological Crystallography 69 (12), 2298-2308, 2013
Unshielding multidrug resistant cancer through selective iron depletion of P-glycoprotein–expressing cells
M Cserepes, D Türk, S Tóth, VFS Pape, A Gaál, M Gera, JE Szabó, ...
Cancer Research 80 (4), 663-674, 2020
Structural model of human dUTPase in complex with a novel proteinaceous inhibitor
K Nyíri, HDT Mertens, B Tihanyi, GN Nagy, B Kőhegyi, J Matejka, ...
Scientific Reports 8 (1), 4326, 2018
Trading in cooperativity for specificity to maintain uracil-free DNA
JE Szabó, E Takács, G Merényi, BG Vértessy, J Tóth
Scientific reports 6 (1), 24219, 2016
In Vitro Analysis of Predicted DNA-Binding Sites for the Stl Repressor of the Staphylococcus aureus SaPIBov1 Pathogenicity Island
V Papp-Kádár, JE Szabó, K Nyíri, BG Vertessy
PLoS One 11 (7), e0158793, 2016
Exploring the role of the phage-specific insert of bacteriophage Φ11 dUTPase
K Nyíri, V Papp-Kádár, JE Szabó, V Németh, BG Vértessy
Structural Chemistry 26, 1425-1432, 2015
A user-friendly, high-throughput tool for the precise fluorescent quantification of deoxyribonucleoside triphosphates from biological samples
JE Szabó, ÉV Surányi, BS Mébold, T Trombitás, M Cserepes, J Tóth
Nucleic Acids Research 48 (8), e45-e45, 2020
dNTPpoolDB: a manually curated database of experimentally determined dNTP pools and pool changes in biological samples
R Pancsa, E Fichó, D Molnár, ÉV Surányi, T Trombitás, D Füzesi, H Lóczi, ...
Nucleic Acids Research, 2021
The role of a key amino acid position in species-specific proteinaceous dUTPase inhibition
A Benedek, F Temesváry-Kis, T Khatanbaatar, I Leveles, ÉV Surányi, ...
Biomolecules 9 (6), 221, 2019
The Role of P-loop in the Enzymatic Mechanism of Nucleotide Pyrophosphatases
I Pecsi, JE Szabo, BG Vertessy, J Toth
Biophysical Journal 98 (3), 449a, 2010
Design, synthesis and biological evaluation of novel cyclic malonamide derivatives as selective RIPK1 inhibitors
JL Petró, G Bényei, P Bana, N Linke, F Horti, JE Szabó, KK Szalai, ...
Bioorganic & Medicinal Chemistry Letters, 129643, 2024
Redox status of cysteines does not alter functional properties of human dUTPase but the Y54C mutation involved in monogenic diabetes decreases protein stability
JE Szabó, K Nyíri, D Andrási, J Matejka, O Ozohanics, B Vértessy
Scientific Reports 11 (1), 19197, 2021
Genomic integrity of virulence genes is preserved by a dUTPase-based molecular switch
J Szabo, V Nemeth, V Papp-Kadar, K Nyiri, I Leveles, A Bendes, ...
dUTPase based switch controls transfer of virulence genes in order to preserve integrity of the transferred mobile genetic elements
JE Szabó, V Németh-Pongrácz, V Papp-Kádár, K Nyíri, B Besztercei, ...
FEBS Journal 280 (Supl 1), 59-60, 2013
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