Role of PCNA and TLS polymerases in D-loop extension during homologous recombination in humans M Sebesta, P Burkovics, S Juhasz, S Zhang, JE Szabo, MYWT Lee, ... DNA repair 12 (9), 691-698, 2013 | 107 | 2013 |
Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control JE Szabo, V Németh, V Papp-Kádár, K Nyíri, I Leveles, AA Bendes, ... Nucleic acids research 42 (19), 11912-11920, 2014 | 59 | 2014 |
Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination I Pécsi, JE Szabó, SD Adams, I Simon, JR Sellers, BG Vértessy, J Tóth Proceedings of the National Academy of Sciences 108 (35), 14437-14442, 2011 | 48 | 2011 |
Life without dUTPase C Kerepesi, JE Szabó, V Papp-Kádár, O Dobay, D Szabó, V Grolmusz, ... Frontiers in microbiology 7, 1768, 2016 | 40 | 2016 |
Cross-species inhibition of dUTPase via the Staphylococcal Stl protein perturbs dNTP pool and colony formation in Mycobacterium R Hirmondó, JE Szabó, K Nyíri, S Tarjányi, P Dobrotka, J Tóth, ... DNA repair 30, 21-27, 2015 | 35 | 2015 |
Structure and enzymatic mechanism of a moonlighting dUTPase I Leveles, V Németh, JE Szabó, V Harmat, K Nyíri, ÁÁ Bendes, ... Acta Crystallographica Section D: Biological Crystallography 69 (12), 2298-2308, 2013 | 35 | 2013 |
Unshielding multidrug resistant cancer through selective iron depletion of P-glycoprotein–expressing cells M Cserepes, D Türk, S Tóth, VFS Pape, A Gaál, M Gera, JE Szabó, ... Cancer Research 80 (4), 663-674, 2020 | 27 | 2020 |
Structural model of human dUTPase in complex with a novel proteinaceous inhibitor K Nyíri, HDT Mertens, B Tihanyi, GN Nagy, B Kőhegyi, J Matejka, ... Scientific Reports 8 (1), 4326, 2018 | 23 | 2018 |
Trading in cooperativity for specificity to maintain uracil-free DNA JE Szabó, E Takács, G Merényi, BG Vértessy, J Tóth Scientific reports 6 (1), 24219, 2016 | 16 | 2016 |
In Vitro Analysis of Predicted DNA-Binding Sites for the Stl Repressor of the Staphylococcus aureus SaPIBov1 Pathogenicity Island V Papp-Kádár, JE Szabó, K Nyíri, BG Vertessy PLoS One 11 (7), e0158793, 2016 | 13 | 2016 |
Exploring the role of the phage-specific insert of bacteriophage Φ11 dUTPase K Nyíri, V Papp-Kádár, JE Szabó, V Németh, BG Vértessy Structural Chemistry 26, 1425-1432, 2015 | 13 | 2015 |
A user-friendly, high-throughput tool for the precise fluorescent quantification of deoxyribonucleoside triphosphates from biological samples JE Szabó, ÉV Surányi, BS Mébold, T Trombitás, M Cserepes, J Tóth Nucleic Acids Research 48 (8), e45-e45, 2020 | 12 | 2020 |
dNTPpoolDB: a manually curated database of experimentally determined dNTP pools and pool changes in biological samples R Pancsa, E Fichó, D Molnár, ÉV Surányi, T Trombitás, D Füzesi, H Lóczi, ... Nucleic Acids Research, 2021 | 9 | 2021 |
The role of a key amino acid position in species-specific proteinaceous dUTPase inhibition A Benedek, F Temesváry-Kis, T Khatanbaatar, I Leveles, ÉV Surányi, ... Biomolecules 9 (6), 221, 2019 | 8 | 2019 |
The Role of P-loop in the Enzymatic Mechanism of Nucleotide Pyrophosphatases I Pecsi, JE Szabo, BG Vertessy, J Toth Biophysical Journal 98 (3), 449a, 2010 | 2 | 2010 |
Design, synthesis and biological evaluation of novel cyclic malonamide derivatives as selective RIPK1 inhibitors JL Petró, G Bényei, P Bana, N Linke, F Horti, JE Szabó, KK Szalai, ... Bioorganic & Medicinal Chemistry Letters 100, 129643, 2024 | 1 | 2024 |
Harnessing dual-mode RIPK1 ligands for cross-species anti-necroptosis inhibitor compounds JL Petró, P Bana, N Linke, JE Szabó, KK Szalai, I Kálomista, CG Vass, ... Bioorganic & Medicinal Chemistry Letters, 129970, 2024 | | 2024 |
Redox status of cysteines does not alter functional properties of human dUTPase but the Y54C mutation involved in monogenic diabetes decreases protein stability JE Szabó, K Nyíri, D Andrási, J Matejka, O Ozohanics, B Vértessy Scientific Reports 11 (1), 19197, 2021 | | 2021 |
Genomic integrity of virulence genes is preserved by a dUTPase-based molecular switch J Szabo, V Nemeth, V Papp-Kadar, K Nyiri, I Leveles, A Bendes, ... EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 42, S134-S134, 2013 | | 2013 |
dUTPase based switch controls transfer of virulence genes in order to preserve integrity of the transferred mobile genetic elements JE Szabó, V Németh-Pongrácz, V Papp-Kádár, K Nyíri, B Besztercei, ... FEBS Journal 280 (Supl 1), 59-60, 2013 | | 2013 |