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Judit E Szabó, PhD
Judit E Szabó, PhD
Richter Gedeon Nyrt.
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Cited by
Cited by
Year
Role of PCNA and TLS polymerases in D-loop extension during homologous recombination in humans
M Sebesta, P Burkovics, S Juhasz, S Zhang, JE Szabo, MYWT Lee, ...
DNA repair 12 (9), 691-698, 2013
1072013
Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control
JE Szabo, V Németh, V Papp-Kádár, K Nyíri, I Leveles, AA Bendes, ...
Nucleic acids research 42 (19), 11912-11920, 2014
592014
Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination
I Pécsi, JE Szabó, SD Adams, I Simon, JR Sellers, BG Vértessy, J Tóth
Proceedings of the National Academy of Sciences 108 (35), 14437-14442, 2011
482011
Life without dUTPase
C Kerepesi, JE Szabó, V Papp-Kádár, O Dobay, D Szabó, V Grolmusz, ...
Frontiers in microbiology 7, 1768, 2016
402016
Cross-species inhibition of dUTPase via the Staphylococcal Stl protein perturbs dNTP pool and colony formation in Mycobacterium
R Hirmondó, JE Szabó, K Nyíri, S Tarjányi, P Dobrotka, J Tóth, ...
DNA repair 30, 21-27, 2015
352015
Structure and enzymatic mechanism of a moonlighting dUTPase
I Leveles, V Németh, JE Szabó, V Harmat, K Nyíri, ÁÁ Bendes, ...
Acta Crystallographica Section D: Biological Crystallography 69 (12), 2298-2308, 2013
352013
Unshielding multidrug resistant cancer through selective iron depletion of P-glycoprotein–expressing cells
M Cserepes, D Türk, S Tóth, VFS Pape, A Gaál, M Gera, JE Szabó, ...
Cancer Research 80 (4), 663-674, 2020
272020
Structural model of human dUTPase in complex with a novel proteinaceous inhibitor
K Nyíri, HDT Mertens, B Tihanyi, GN Nagy, B Kőhegyi, J Matejka, ...
Scientific Reports 8 (1), 4326, 2018
232018
Trading in cooperativity for specificity to maintain uracil-free DNA
JE Szabó, E Takács, G Merényi, BG Vértessy, J Tóth
Scientific reports 6 (1), 24219, 2016
162016
In Vitro Analysis of Predicted DNA-Binding Sites for the Stl Repressor of the Staphylococcus aureus SaPIBov1 Pathogenicity Island
V Papp-Kádár, JE Szabó, K Nyíri, BG Vertessy
PLoS One 11 (7), e0158793, 2016
132016
Exploring the role of the phage-specific insert of bacteriophage Φ11 dUTPase
K Nyíri, V Papp-Kádár, JE Szabó, V Németh, BG Vértessy
Structural Chemistry 26, 1425-1432, 2015
132015
A user-friendly, high-throughput tool for the precise fluorescent quantification of deoxyribonucleoside triphosphates from biological samples
JE Szabó, ÉV Surányi, BS Mébold, T Trombitás, M Cserepes, J Tóth
Nucleic Acids Research 48 (8), e45-e45, 2020
122020
dNTPpoolDB: a manually curated database of experimentally determined dNTP pools and pool changes in biological samples
R Pancsa, E Fichó, D Molnár, ÉV Surányi, T Trombitás, D Füzesi, H Lóczi, ...
Nucleic Acids Research, 2021
92021
The role of a key amino acid position in species-specific proteinaceous dUTPase inhibition
A Benedek, F Temesváry-Kis, T Khatanbaatar, I Leveles, ÉV Surányi, ...
Biomolecules 9 (6), 221, 2019
82019
The Role of P-loop in the Enzymatic Mechanism of Nucleotide Pyrophosphatases
I Pecsi, JE Szabo, BG Vertessy, J Toth
Biophysical Journal 98 (3), 449a, 2010
22010
Design, synthesis and biological evaluation of novel cyclic malonamide derivatives as selective RIPK1 inhibitors
JL Petró, G Bényei, P Bana, N Linke, F Horti, JE Szabó, KK Szalai, ...
Bioorganic & Medicinal Chemistry Letters 100, 129643, 2024
12024
Harnessing dual-mode RIPK1 ligands for cross-species anti-necroptosis inhibitor compounds
JL Petró, P Bana, N Linke, JE Szabó, KK Szalai, I Kálomista, CG Vass, ...
Bioorganic & Medicinal Chemistry Letters, 129970, 2024
2024
Redox status of cysteines does not alter functional properties of human dUTPase but the Y54C mutation involved in monogenic diabetes decreases protein stability
JE Szabó, K Nyíri, D Andrási, J Matejka, O Ozohanics, B Vértessy
Scientific Reports 11 (1), 19197, 2021
2021
Genomic integrity of virulence genes is preserved by a dUTPase-based molecular switch
J Szabo, V Nemeth, V Papp-Kadar, K Nyiri, I Leveles, A Bendes, ...
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 42, S134-S134, 2013
2013
dUTPase based switch controls transfer of virulence genes in order to preserve integrity of the transferred mobile genetic elements
JE Szabó, V Németh-Pongrácz, V Papp-Kádár, K Nyíri, B Besztercei, ...
FEBS Journal 280 (Supl 1), 59-60, 2013
2013
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