| A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635 EA Forster, IA Cliffe, DJ Bill, GM Dover, D Jones, Y Reilly, A Fletcher European journal of pharmacology 281 (1), 81-88, 1995 | 662 | 1995 |
| Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist A Fletcher, EA Forster, DJ Bill, G Brown, IA Cliffe, JE Hartley, DE Jones, ... Behavioural brain research 73 (1-2), 337-353, 1995 | 582 | 1995 |
| Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H] WAY-100635 and [11C] way-100635 H Hall, C Lundkvist, C Halldin, L Farde, VW Pike, JA McCarron, A Fletcher, ... Brain research 745 (1-2), 96-108, 1997 | 328 | 1997 |
| Silent 5-HT1A receptor antagonists: utility as research tools and therapeutic agents A Fletcher, IA Cliffe, CT Dourish Trends in Pharmacological Sciences 14 (12), 441-448, 1993 | 273 | 1993 |
| WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A receptors A Fletcher, DJ Bill, SJ Bill, IA Cliffe, GM Dover, EA Forster, JT Haskins, ... European journal of pharmacology 237 (2-3), 283-291, 1993 | 264 | 1993 |
| Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11C] WAY-100635 VW Pike, JA McCarron, AA Lammertsma, S Osman, SP Hume, ... European journal of pharmacology 301 (1-3), R5-R7, 1996 | 258 | 1996 |
| First delineation of 5-HT1A receptors in human brain with PET and [11C] WAY-100635 VW Pike, JA McCarron, AA Lammerstma, SP Hume, K Poole, PM Grasby, ... European journal of pharmacology 283 (1-3), R1-R3, 1995 | 140 | 1995 |
| A pharmacological profile of WAY-100635, a potent and selective 5-HT1A receptor antagonist A Fletcher, DJ Bill, IA Cliffe, EA Forster, D Jones, Y Reilly British Journal of Pharmacology-Proceedings Supplement 112, 91P, 1994 | 138 | 1994 |
| Discovery of nonxanthine adenosine A2A receptor antagonists for the treatment of Parkinson’s disease SM Weiss, K Benwell, IA Cliffe, RJ Gillespie, AR Knight, J Lerpiniere, ... Neurology 61 (11_suppl_6), S101-S106, 2003 | 110 | 2003 |
| Characterization of the radioactive metabolites of the 5-HT1A receptor radioligand,[O-methl-11C] WAY-100635, in monkey and human plasma by HPLC: comparison of the behaviour of … S Osman, C Lundkvist, VW Pike, C Halldin, JA McCarron, CG Swahn, ... Nuclear medicine and biology 23 (5), 627-634, 1996 | 107 | 1996 |
| (S)-N-tert-Butyl-3-(4-(2-methoxyphenyl) piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors IA Cliffe, CI Brightwell, A Fletcher, EA Forster, HL Mansell, Y Reilly, ... Journal of medicinal chemistry 36 (10), 1509-1510, 1993 | 105 | 1993 |
| PRE-CLINICAL DEVELOPMENT OF A RADIOLIGAND FOR STUDIES OF CENTRAL 5-HT1A RECEPTORS IN VIVO-(11C) WAY-100635 VW Pike, JA McCarron, SP Hume, S Ashworth, J Opacka-Juffry, S Osman, ... Medicinal Chemistry Research 5 (2), 208-227, 1995 | 88 | 1995 |
| Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo [3, 4-d] pyrimidines, pyrrolo [2, 3-d] pyrimidines and 6-arylpurines RJ Gillespie, IA Cliffe, CE Dawson, CT Dourish, S Gaur, AM Jordan, ... Bioorganic & medicinal chemistry letters 18 (9), 2924-2929, 2008 | 82 | 2008 |
| Evaluation of [O-methyl-3H] WAY-100635 as an in vivo radioligand for 5-HT1A receptors in rat brain SP Hume, S Ashworth, J Opacka-Juffry, RG Ahier, AA Lammertsma, ... European journal of pharmacology 271 (2-3), 515-523, 1994 | 82 | 1994 |
| N-((phenyl, benzodioxinyl or N-heteroarylpiperazinyl) alkyl)-N-(N-heteroaryl) substituted carboxamides IA Cliffe, HL Mansell US Patent 6,127,357, 2000 | 76 | 2000 |
| Tertiary alkyl functionalized piperazine derivatives MA Abou-Gharbia, JP Yardley, IA Cliffe US Patent 4,988,814, 1991 | 74 | 1991 |
| A retrospect on the discovery of WAY-100635 and the prospect for improved 5-HT1A receptor PET radioligands IA Cliffe Nuclear medicine and biology 27 (5), 441-447, 2000 | 62 | 2000 |
| Antagonists of the human adenosine A2A receptor. Part 1: Discovery and synthesis of thieno [3, 2-d] pyrimidine-4-methanone derivatives RJ Gillespie, DR Adams, D Bebbington, K Benwell, IA Cliffe, CE Dawson, ... Bioorganic & medicinal chemistry letters 18 (9), 2916-2919, 2008 | 54 | 2008 |
| 4-quinolinemethanol derivatives as purine receptor antagonists (II) RJ Gillespie, J Lerpiniere, PR Giles, DR Adams, LJS Knutsen, IA Cliffe US Patent 6,608,085, 2003 | 47 | 2003 |
| Advances in 5-HT~ 1~ A antagonist research IA Cliffe, A Fletcher Drugs of the Future 18, 631-631, 1993 | 47 | 1993 |
