| Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C … KA Piróg-Garcia, RS Meadows, L Knowles, D Heinegård, DJ Thornton, ... Human molecular genetics 16 (17), 2072-2088, 2007 | 95 | 2007 |
| A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia KA Pirog, O Jaka, Y Katakura, RS Meadows, KE Kadler, ... Human molecular genetics 19 (1), 52-64, 2010 | 59 | 2010 |
| A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia F Suleman, B Gualeni, HJ Gregson, MP Leighton, KA Piróg, S Edwards, ... Human mutation 33 (1), 218-231, 2012 | 53 | 2012 |
| Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and … TL Cameron, IL Gresshoff, KM Bell, KA Piróg, L Sampurno, CL Hartley, ... Osteoarthritis and cartilage 23 (4), 661-670, 2015 | 45 | 2015 |
| New therapeutic targets in rare genetic skeletal diseases MD Briggs, PA Bell, MJ Wright, KA Pirog Expert opinion on orphan drugs 3 (10), 1137-1154, 2015 | 38 | 2015 |
| The utility of mouse models to provide information regarding the pathomolecular mechanisms in human genetic skeletal diseases: The emerging role of endoplasmic reticulum stress MD Briggs, PA Bell, KA Pirog International journal of molecular medicine 35 (6), 1483-1492, 2015 | 36 | 2015 |
| Abnormal chondrocyte apoptosis in the cartilage growth plate is influenced by genetic background and deletion of CHOP in a targeted mouse model of pseudoachondroplasia KA Piróg, A Irman, S Young, P Halai, PA Bell, RP Boot-Handford, ... PloS one 9 (2), e85145, 2014 | 35 | 2014 |
| Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification C Paganini, L Monti, R Costantini, R Besio, S Lecci, M Biggiogera, K Tian, ... Matrix Biology 81, 70-90, 2019 | 34 | 2019 |
| Mesencephalic astrocyte-derived neurotropic factor is an important factor in chondrocyte ER homeostasis PA Bell, EP Dennis, CL Hartley, RM Jackson, A Porter, RP Boot-Handford, ... Cell Stress and Chaperones 24 (1), 159-173, 2019 | 25 | 2019 |
| Skeletal Dysplasias Associated with Mild Myopathy—A Clinical and Molecular Review A Katarzyna, MD Briggs | 23 | 2010 |
| XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease KA Pirog, EP Dennis, CL Hartley, RM Jackson, J Soul, JM Schwartz, ... PLoS Genetics 15 (7), e1008215, 2019 | 22 | 2019 |
| New developments in chondrocyte ER stress and related diseases MD Briggs, EP Dennis, HF Dietmar, KA Pirog F1000Research 9, 2020 | 21 | 2020 |
| microRNA-seq of cartilage reveals an overabundance of miR-140-3p which contains functional isomiRs S Woods, S Charlton, K Cheung, Y Hao, J Soul, LN Reynard, N Crowe, ... Rna 26 (11), 1575-1588, 2020 | 20 | 2020 |
| CRELD2 is a novel LRP1 chaperone that regulates noncanonical WNT signaling in skeletal development EP Dennis, SM Edwards, RM Jackson, CL Hartley, D Tsompani, M Capulli, ... Journal of Bone and Mineral Research 35 (8), 1452-1469, 2020 | 18 | 2020 |
| Increased hippocampal excitability in miR-324-null mice DJ Hayman, T Modebadze, S Charlton, K Cheung, J Soul, H Lin, Y Hao, ... Scientific reports 11 (1), 10452, 2021 | 10 | 2021 |
| Mild myopathy is associated with COMP but not MATN3 mutations in mouse models of genetic skeletal diseases KA Piróg, Y Katakura, A Mironov, MD Briggs PloS one 8 (11), e82412, 2013 | 10 | 2013 |
| Loss of matrilin 1 does not exacerbate the skeletal phenotype in a mouse model of multiple epiphyseal dysplasia caused by a Matn3 V194D mutation PA Bell, KA Piróg, M Fresquet, DJ Thornton, RP Boot‐Handford, ... Arthritis & Rheumatism 64 (5), 1529-1539, 2012 | 9 | 2012 |
| Changes in Bcl-2 expression in vaccinia virus-infected human peripheral blood monocytes KA Pirog, AK Kowalczyk, HB Rokita Viral Immunology 18 (1), 224-231, 2005 | 3 | 2005 |
| Pseudoachondroplasia and multiple epiphyseal dysplasia: Molecular genetics, disease mechanisms and therapeutic targets MD Briggs, P Bell, KA Piróg Cartilage: Volume 2: Pathophysiology, 135-153, 2017 | 2 | 2017 |
| Involvement of kinesins in skeletal dysplasia-a review R Bouchenafa, FM de Sousa Brito, KA Pirog American Journal of Physiology-Cell Physiology, 2024 | | 2024 |
