In vivo discovery of a peptide that prevents CUG–RNA hairpin formation and reverses RNA toxicity in myotonic dystrophy models A García-López, B Llamusí, M Orzáez, E Pérez-Payá, RD Artero Proceedings of the National Academy of Sciences 108 (29), 11866-11871, 2011 | 126 | 2011 |
Increased autophagy and apoptosis contribute to muscle atrophy in a myotonic dystrophy type 1 Drosophila model A Bargiela, E Cerro-Herreros, JM Fernandez-Costa, JJ Vilchez, B Llamusi, ... Disease models & mechanisms 8 (7), 679-690, 2015 | 90 | 2015 |
Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster J Iyer, Q Wang, T Le, L Pizzo, S Grönke, SS Ambegaokar, Y Imai, ... G3: Genes, Genomes, Genetics 6 (5), 1427-1437, 2016 | 81 | 2016 |
miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models E Cerro-Herreros, M Sabater-Arcis, JM Fernandez-Costa, N Moreno, ... Nature Communications 9 (1), 2482, 2018 | 75 | 2018 |
Chronic spinal injury repair by olfactory bulb ensheathing glia and feasibility for autologous therapy C Muñoz-Quiles, FF Santos-Benito, MB Llamusí, A Ramón-Cueto Journal of Neuropathology & Experimental Neurology 68 (12), 1294-1308, 2009 | 68 | 2009 |
rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences C Sellier, E Cerro-Herreros, M Blatter, F Freyermuth, A Gaucherot, ... Nature communications 9 (1), 2009, 2018 | 65 | 2018 |
Alternative splicing regulation by Muscleblind proteins: from development to disease JM Fernandez‐Costa, MB Llamusi, A Garcia‐Lopez, R Artero Biological Reviews 86 (4), 947-958, 2011 | 62 | 2011 |
Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model B Llamusi, A Bargiela, JM Fernandez-Costa, A Garcia-Lopez, R Klima, ... Disease models & mechanisms 6 (1), 184-196, 2013 | 52 | 2013 |
RNA-mediated therapies in myotonic dystrophy SJ Overby, E Cerro-Herreros, B Llamusi, R Artero Drug discovery today 23 (12), 2013-2022, 2018 | 48 | 2018 |
Derepressing muscleblind expression by miRNA sponges ameliorates myotonic dystrophy-like phenotypes in Drosophila E Cerro-Herreros, JM Fernandez-Costa, M Sabater-Arcis, B Llamusi, ... Scientific reports 6 (1), 36230, 2016 | 48 | 2016 |
Pentamidine rescues contractility and rhythmicity in a Drosophila model of myotonic dystrophy heart dysfunction M Chakraborty, E Selma-Soriano, E Magny, JP Couso, M Pérez-Alonso, ... Disease models & mechanisms 8 (12), 1569-1578, 2015 | 38 | 2015 |
Therapeutic potential of AntagomiR-23b for treating myotonic dystrophy E Cerro-Herreros, I González-Martínez, N Moreno-Cervera, S Overby, ... Molecular Therapy-Nucleic Acids 21, 837-849, 2020 | 37 | 2020 |
Molecular effects of the CTG repeats in mutant dystrophia myotonica protein kinase gene B Llamusí, R Artero Current genomics 9 (8), 509-516, 2008 | 35 | 2008 |
Bioengineered in vitro 3D model of myotonic dystrophy type 1 human skeletal muscle X Fernandez-Garibay, MA Ortega, E Cerro-Herreros, J Comelles, ... Biofabrication 13 (3), 035035, 2021 | 26 | 2021 |
Two Enhancers Control Transcription of Drosophila muscleblind in the Embryonic Somatic Musculature and in the Central Nervous System A Bargiela, B Llamusi, E Cerro-Herreros, R Artero PloS one 9 (3), e93125, 2014 | 19 | 2014 |
The Drosophila junctophilin gene is functionally equivalent to its four mammalian counterparts and is a modifier of a Huntingtin poly-Q expansion and the Notch … E Calpena, V Lopez del Amo, M Chakraborty, B Llamusí, R Artero, ... Disease Models & Mechanisms 11 (1), dmm029082, 2018 | 18 | 2018 |
Expanded CCUG repeat RNA expression in Drosophila heart and muscle trigger Myotonic Dystrophy type 1-like phenotypes and activate autophagocytosis genes E Cerro-Herreros, M Chakraborty, M Pérez-Alonso, R Artero, B Llamusí Scientific Reports 7 (1), 2843, 2017 | 17 | 2017 |
In silico discovery of substituted pyrido[2,3-d]pyrimidines and pentamidine-like compounds with biological activity in myotonic dystrophy models ÀL González, P Konieczny, B Llamusi, E Delgado-Pinar, JI Borrell, ... PLoS One 12 (6), e0178931, 2017 | 16 | 2017 |
Proof of concept of peptide-linked blockmiR-induced MBNL functional rescue in myotonic dystrophy type 1 mouse model SJ Overby, E Cerro-Herreros, I González-Martínez, MA Varela, ... Molecular Therapy-Nucleic Acids 27, 1146-1155, 2022 | 14 | 2022 |
Preclinical characterization of antagomiR-218 as a potential treatment for myotonic dystrophy E Cerro-Herreros, I González-Martínez, N Moreno, J Espinosa-Espinosa, ... Molecular Therapy-Nucleic Acids 26, 174-191, 2021 | 14 | 2021 |