Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety AB Burgin, OT Magnusson, J Singh, P Witte, BL Staker, JM Bjornsson, ... Nature biotechnology 28 (1), 63-70, 2010 | 412 | 2010 |
Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31 U Styrkarsdottir, G Thorleifsson, HT Helgadottir, N Bomer, S Metrustry, ... Nature genetics 46 (5), 498-502, 2014 | 169 | 2014 |
Effects of 2, 4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy MER Butchbach, J Singh, M Þorsteinsdóttir, L Saieva, E Slominski, ... Human molecular genetics 19 (3), 454-467, 2010 | 151 | 2010 |
Synthesis and Biological Evaluation of Novel 2,4-Diaminoquinazoline Derivatives as SMN2 Promoter Activators for the Potential Treatment of Spinal Muscular … J Thurmond, MER Butchbach, M Palomo, B Pease, M Rao, L Bedell, ... Journal of medicinal chemistry 51 (3), 449-469, 2008 | 111 | 2008 |
Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administration HH Sigurdsson, E Stefánsson, E Gudmundsdóttir, T Eysteinsson, ... Journal of Controlled Release 102 (1), 255-262, 2005 | 92 | 2005 |
Discovery of 4-[(2S)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic Acid (DG-051) as a Novel Leukotriene A4 Hydrolase Inhibitor of Leukotriene … V Sandanayaka, B Mamat, RK Mishra, J Winger, M Krohn, LM Zhou, ... Journal of medicinal chemistry 53 (2), 573-585, 2010 | 91 | 2010 |
Cyclodextrin solubilization of carbonic anhydrase inhibitor drugs: formulation of dorzolamide eye drop microparticle suspension P Jansook, E Stefánsson, M Thorsteinsdóttir, BB Sigurdsson, ... European journal of pharmaceutics and biopharmaceutics 76 (2), 208-214, 2010 | 89 | 2010 |
Antagonists of the EP3 Receptor for Prostaglandin E2 Are Novel Antiplatelet Agents That Do Not Prolong Bleeding J Singh, W Zeller, N Zhou, G Hategen, R Mishra, A Polozov, P Yu, E Onua, ... ACS chemical biology 4 (2), 115-126, 2009 | 86 | 2009 |
Dexamethasone eye drops containing γ-cyclodextrin-based nanogels MD Moya-Ortega, TFG Alves, C Alvarez-Lorenzo, A Concheiro, ... International journal of pharmaceutics 441 (1-2), 507-515, 2013 | 79 | 2013 |
Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease A Helgadottir, G Thorleifsson, KF Alexandersson, V Tragante, ... European heart journal 41 (28), 2618-2628, 2020 | 69 | 2020 |
Cellular and molecular mechanisms of kidney injury in 2, 8-dihydroxyadenine nephropathy BM Klinkhammer, S Djudjaj, U Kunter, R Palsson, VO Edvardsson, ... Journal of the American society of nephrology 31 (4), 799-816, 2020 | 67 | 2020 |
Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis G Schley, B Klanke, J Kalucka, V Schatz, C Daniel, M Mayer, ... Kidney international 96 (2), 378-396, 2019 | 57 | 2019 |
Structure−Activity Relationship Studies Leading to the Identification of (2E)-3-[l-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-lH-indol-7-yl]-N-[(4,5-dichloro-2 … J Singh, W Zeller, N Zhou, G Hategan, RK Mishra, A Polozov, P Yu, ... Journal of medicinal chemistry 53 (1), 18-36, 2010 | 53 | 2010 |
Kinetics of γ‐cyclodextrin nanoparticle suspension eye drops in tear fluid G Jóhannesson, MD Moya‐Ortega, GM Ásgrímsdóttir, SH Lund, ... Acta ophthalmologica 92 (6), 550-556, 2014 | 51 | 2014 |
Performance of amino‐silylated fused‐silica capillaries for the separation of enkephalin‐related peptides by capillary zone electrophoresis and micellar electrokinetic … M Thorsteinsdóttir, R Isaksson, D Westerlund Electrophoresis 16 (1), 557-563, 1995 | 44 | 1995 |
Natural products from bryophytes: from basic biology to biotechnological applications A Horn, A Pascal, I Lončarević, R Volpatto Marques, Y Lu, S Miguel, ... Critical Reviews in Plant Sciences 40 (3), 191-217, 2021 | 42 | 2021 |
Lipidomic study of cell lines reveals differences between breast cancer subtypes FF Eiriksson, MK Nøhr, M Costa, SK Bödvarsdottir, HM Ögmundsdottir, ... PLoS One 15 (4), e0231289, 2020 | 41 | 2020 |
Comparison of the effect of allopurinol and febuxostat on urinary 2, 8-dihydroxyadenine excretion in patients with adenine phosphoribosyltransferase deficiency (APRTd): a … VO Edvardsson, HL Runolfsdottir, UA Thorsteinsdottir, IMS Agustsdottir, ... European journal of internal medicine 48, 75-79, 2018 | 38 | 2018 |
Valuable fatty acids in bryophytes—Production, biosynthesis, analysis and applications Y Lu, FF Eiriksson, M Thorsteinsdóttir, HT Simonsen Plants 8 (11), 524, 2019 | 33 | 2019 |
Authentication of Iceland Moss (Cetraria islandica) by UPLC-QToF-MS chemical profiling and DNA barcoding M Xu, S Heidmarsson, M Thorsteinsdottir, M Kreuzer, J Hawkins, ... Food Chemistry 245, 989-996, 2018 | 30 | 2018 |