József Tőzsér
József Tőzsér
Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen
E-mail megerősítve itt: med.unideb.hu
CímIdézteÉv
Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency
RB Kapust, J Tözsér, JD Fox, DE Anderson, S Cherry, TD Copeland, ...
Protein engineering 14 (12), 993-1000, 2001
7152001
The P1′ specificity of tobacco etch virus protease
RB Kapust, J Tözsér, TD Copeland, DS Waugh
Biochemical and biophysical research communications 294 (5), 949-955, 2002
3392002
Comparison of the HIV‐1 and HIV‐2 proteinases using oligopeptide substrates representing cleavage sites in Gag and Gag‐Pol polyproteins
J Tözsér, I Bláha, TD Copeland, EM Wondrak, S Oroszlan
FEBS letters 281 (1-2), 77-80, 1991
1601991
Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease
T Sperka, J Pitlik, P Bagossi, J Tözsér
Bioorganic & medicinal chemistry letters 15 (12), 3086-3090, 2005
1472005
Efficient site-specific processing of fusion proteins by tobacco vein mottling virus protease in vivo and in vitro
S Nallamsetty, RB Kapust, J Tözsér, S Cherry, JE Tropea, TD Copeland, ...
Protein expression and purification 38 (1), 108-115, 2004
1172004
Kinetic and modeling studies of S3-S3'subsites of HIV proteinases
J Tozser, IT Weber, A Gustchina, I Blaha, TD Copeland, JM Louis, ...
Biochemistry 31 (20), 4793-4800, 1992
1141992
Folded monomer of HIV-1 protease
R Ishima, R Ghirlando, J Tözsér, AM Gronenborn, DA Torchia, JM Louis
Journal of Biological Chemistry 276 (52), 49110-49116, 2001
992001
Atomic resolution crystal structures of HIV‐1 protease and mutants V82A and I84V with saquinavir
Y Tie, AY Kovalevsky, P Boross, YF Wang, AK Ghosh, J Tozser, ...
Proteins: Structure, Function, and Bioinformatics 67 (1), 232-242, 2007
892007
HIV-I protease: Maturation, enzyme specificity, and drug resistance
JM Louis, IT Webert, J Tözsér, GM Clore, AM Gronenborn
Advances in pharmacology 49, 111-146, 2000
882000
Substitution of proline with pipecolic acid at the scissile bond converts a peptide substrate of HIV proteinase into a selective inhibitor
TD Copeland, EM Wondrak, J Tozser, MM Roberts, S Oroszlan
Biochemical and biophysical research communications 169 (1), 310-314, 1990
851990
Effect of sequence polymorphism and drug resistance on two HIV‐1 Gag processing sites
A Fehér, IT Weber, P Bagossi, P Boross, B Mahalingam, JM Louis, ...
European journal of biochemistry 269 (16), 4114-4120, 2002
832002
Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages
MM Budai, A Varga, S Milesz, J Tőzsér, S Benkő
Molecular immunology 56 (4), 471-479, 2013
822013
Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 Å resolution crystal structures of HIV‐1 protease mutants with substrate analogs
Y Tie, PI Boross, YF Wang, L Gaddis, F Liu, X Chen, J Tozser, ...
The FEBS journal 272 (20), 5265-5277, 2005
792005
Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S
F Liu, PI Boross, YF Wang, J Tozser, JM Louis, RW Harrison, IT Weber
Journal of molecular biology 354 (4), 789-800, 2005
772005
Studies on the role of the S4 substrate binding site of HIV proteinases
J Tözsér, A Gustchina, IT Weber, I Blaha, EM Wondrak, S Oroszlan
FEBS letters 279 (2), 356-360, 1991
751991
Crystal structures of HIV protease V82A and L90M mutants reveal changes in the indinavir‐binding site
B Mahalingam, YF Wang, PI Boross, J Tozser, JM Louis, RW Harrison, ...
European journal of biochemistry 271 (8), 1516-1524, 2004
722004
Combining mutations in HIV‐1 protease to understand mechanisms of resistance
B Mahalingam, P Boross, YF Wang, JM Louis, CC Fischer, J Tozser, ...
Proteins: Structure, Function, and Bioinformatics 48 (1), 107-116, 2002
662002
Quantitative analysis of proteins in the tear fluid of patients with diabetic retinopathy
É Csősz, P Boross, A Csutak, A Berta, F Tóth, S Póliska, Z Török, J Tőzsér
Journal of proteomics 75 (7), 2196-2204, 2012
642012
Research applications of proteolytic enzymes in molecular biology
J Mótyán, F Tóth, J Tőzsér
Biomolecules 3 (4), 923-942, 2013
632013
HIV inhibitors: problems and reality
JÓ TÖzsÉr
Annals of the New York Academy of Sciences 946 (1), 145-159, 2001
592001
A rendszer jelenleg nem tudja elvégezni a műveletet. Próbálkozzon újra később.
Cikkek 1–20