| Isolation and characterization of MC3T3‐E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential D Wang, K Christensen, K Chawla, G Xiao, PH Krebsbach, ... Journal of Bone and Mineral Research 14 (6), 893-903, 1999 | 810 | 1999 |
| Regulation of the osteoblast‐specific transcription factor, Runx2: Responsiveness to multiple signal transduction pathways RT Franceschi, G Xiao Journal of cellular biochemistry 88 (3), 446-454, 2003 | 692 | 2003 |
| MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1 G Xiao, D Jiang, P Thomas, MD Benson, K Guan, G Karsenty, ... Journal of Biological Chemistry 275 (6), 4453-4459, 2000 | 688 | 2000 |
| Cell-interactive alginate hydrogels for bone tissue engineering E Alsberg, KW Anderson, A Albeiruti, RT Franceschi, DJ Mooney Journal of dental research 80 (11), 2025-2029, 2001 | 682 | 2001 |
| Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3‐E1 cells RT Franceschi, BS Iyer Journal of Bone and Mineral Research 7 (2), 235-246, 1992 | 675 | 1992 |
| Engineering new bone tissue in vitro on highly porous poly(α‐hydroxyl acids)/hydroxyapatite composite scaffolds PX Ma, R Zhang, G Xiao, R Franceschi Journal of Biomedical Materials Research: An Official Journal of The Society …, 2001 | 599 | 2001 |
| Effects of ascorbic acid on collagen matrix formation and osteoblast differentiation in murine MC3T3 E1 cells RT Franceschi, BS Iyer, Y Cui Journal of bone and mineral research 9 (6), 843-854, 1994 | 550 | 1994 |
| Critical role of the extracellular signal–regulated kinase–MAPK pathway in osteoblast differentiation and skeletal development C Ge, G Xiao, DI Jiang, RT Franceschi The Journal of cell biology 176 (5), 709-718, 2007 | 546 | 2007 |
| Bone morphogenetic proteins, extracellular matrix, and mitogen‐activated protein kinase signaling pathways are required for osteoblast‐specific gene expression and … G Xiao, R Gopalakrishnan, D Jiang, E Reith, MD Benson, RT Franceschi Journal of bone and mineral research 17 (1), 101-110, 2002 | 527 | 2002 |
| Inhibition of osteoblastic bone formation by nuclear factor-κB J Chang, Z Wang, E Tang, Z Fan, L McCauley, R Franceschi, K Guan, ... Nature medicine 15 (6), 682-689, 2009 | 522 | 2009 |
| Role of the α2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor G Xiao, D Wang, MD Benson, G Karsenty, RT Franceschi Journal of Biological Chemistry 273 (49), 32988-32994, 1998 | 469 | 1998 |
| Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2 G Xiao, D Jiang, R Gopalakrishnan, RT Franceschi Journal of Biological Chemistry 277 (39), 36181-36187, 2002 | 459 | 2002 |
| BMP signaling is required for RUNX2‐dependent induction of the osteoblast phenotype M Phimphilai, Z Zhao, H Boules, H Roca, RT Franceschi Journal of Bone and Mineral Research 21 (4), 637-646, 2006 | 454 | 2006 |
| Transcriptional regulation of osteoblasts RT Franceschi, C Ge, G Xiao, H Roca, DI Jiang Annals of the New York Academy of Sciences 1116 (1), 196-207, 2007 | 413 | 2007 |
| The developmental control of osteoblast-specific gene expression: role of specific transcription factors and the extracellular matrix environment RT Franceschi Critical Reviews in Oral Biology & Medicine 10 (1), 40-57, 1999 | 338 | 1999 |
| Gene therapy-directed osteogenesis: BMP-7-transduced human fibroblasts form bone in vivo PH Krebsbach, K Gu, RT Franceschi, RB Rutherford Human gene therapy 11 (8), 1201-1210, 2000 | 332 | 2000 |
| Gene therapy for bone formation: in vitro and in vivo osteogenic activity of an adenovirus expressing BMP7 RT Franceschi, D Wang, PH Krebsbach, RB Rutherford Journal of cellular biochemistry 78 (3), 476-486, 2000 | 318 | 2000 |
| Multiple signaling pathways converge on the Cbfa1/Runx2 transcription factor to regulate osteoblast differentiation RT Franceschi, G Xiao, D Jiang, R Gopalakrishnan, S Yang, E Reith Connective tissue research 44 (1), 109-116, 2003 | 317 | 2003 |
| Engineered bone development from a pre-osteoblast cell line on three-dimensional scaffolds LD Shea, D Wang, RT Franceschi, DJ Mooney Tissue engineering 6 (6), 605-617, 2000 | 308 | 2000 |
| Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression G Xiao, D Jiang, C Ge, Z Zhao, Y Lai, H Boules, M Phimphilai, X Yang, ... Journal of Biological Chemistry 280 (35), 30689-30696, 2005 | 294 | 2005 |
