Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators SST Lee, T Pineau, J Drago, EJ Lee, JW Owens, DL Kroetz, ... Molecular and cellular biology 15 (6), 3012-3022, 1995 | 1987 | 1995 |
Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C> T affects mRNA stability D Wang, AD Johnson, AC Papp, DL Kroetz, W Sadee Pharmacogenetics and genomics 15 (10), 693-704, 2005 | 650 | 2005 |
Human liver carbamazepine metabolism: role of CYP3A4 and CYP2C8 in 10, 11-epoxide formation BM Kerr, KE Thummel, CJ Wurden, SM Klein, DL Kroetz, FJ Gonzalez, ... Biochemical pharmacology 47 (11), 1969-1979, 1994 | 594 | 1994 |
Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids Z Yu, F Xu, LM Huse, C Morisseau, AJ Draper, JW Newman, C Parker, ... Circulation research 87 (11), 992-998, 2000 | 587 | 2000 |
Very important pharmacogene summary LM Hodges, SM Markova, LW Chinn, JM Gow, DL Kroetz, TE Klein, ... Pharmacogenetics and genomics 21 (3), 152-161, 2011 | 536 | 2011 |
Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene DL Kroetz, C Pauli-Magnus, LM Hodges, CC Huang, M Kawamoto, ... Pharmacogenetics and Genomics 13 (8), 481-494, 2003 | 512 | 2003 |
The pharmacogenetics research network: from SNP discovery to clinical drug response KM Giacomini, CM Brett, RB Altman, NL Benowitz, ME Dolan, ... Clinical Pharmacology & Therapeutics 81 (3), 328-345, 2007 | 312 | 2007 |
Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics F Innocenti, DL Kroetz, E Schuetz, ME Dolan, J Ramírez, M Relling, ... Journal of Clinical Oncology 27 (16), 2604-2614, 2009 | 301 | 2009 |
Natural variation in human membrane transporter genes reveals evolutionary and functional constraints MK Leabman, CC Huang, J DeYoung, EJ Carlson, TR Taylor, ... Proceedings of the National Academy of Sciences 100 (10), 5896-5901, 2003 | 275 | 2003 |
Peroxisome proliferator-activated receptor α controls the hepatic CYP4A induction adaptive response to starvation and diabetes DL Kroetz, P Yook, P Costet, P Bianchi, T Pineau Journal of Biological Chemistry 273 (47), 31581-31589, 1998 | 267 | 1998 |
Cytochrome P450 pathways of arachidonic acid metabolism DL Kroetz, DC Zeldin Current opinion in lipidology 13 (3), 273-283, 2002 | 265 | 2002 |
Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA‐B Genotype and Abacavir Dosing MA Martin, TE Klein, BJ Dong, M Pirmohamed, DW Haas, DL Kroetz Clinical Pharmacology & Therapeutics 91 (4), 734-738, 2012 | 245 | 2012 |
A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101 RM Baldwin, K Owzar, H Zembutsu, A Chhibber, M Kubo, C Jiang, ... Clinical Cancer Research 18 (18), 5099-5109, 2012 | 232 | 2012 |
Adherence-resistance relationships to combination HIV antiretroviral therapy DR Bangsberg, DL Kroetz, SG Deeks Current HIV/AIDS Reports 4 (2), 65-72, 2007 | 231 | 2007 |
Evolutionary conservation of vertebrate blood–brain barrier chemoprotective mechanisms in Drosophila F Mayer, N Mayer, L Chinn, RL Pinsonneault, D Kroetz, RJ Bainton Journal of Neuroscience 29 (11), 3538-3550, 2009 | 218 | 2009 |
Irinotecan‐induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein FA De Jong, TJ Scott‐Horton, DL Kroetz, HL McLeod, LE Friberg, ... Clinical Pharmacology & Therapeutics 81 (1), 42-49, 2007 | 200 | 2007 |
The effects of a diet rich in docosahexaenoic acid on organ and vascular fatty acid composition in spontaneously hypertensive rats MM Engler, MB Engler, DL Kroetz, KDB Boswell, E Neeley, SM Krassner Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 61 (5), 289-295, 1999 | 198 | 1999 |
Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa S Parikh, JB Ouedraogo, JA Goldstein, PJ Rosenthal, DL Kroetz Clinical Pharmacology & Therapeutics 82 (2), 197-203, 2007 | 196 | 2007 |
Genome-wide association studies in pharmacogenomics: successes and lessons AA Motsinger-Reif, E Jorgenson, MV Relling, DL Kroetz, R Weinshilboum, ... Pharmacogenetics and genomics 23 (8), 383-394, 2013 | 187 | 2013 |
Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor α VY Ng, Y Huang, LM Reddy, JR Falck, ET Lin, DL Kroetz Drug Metabolism and Disposition 35 (7), 1126-1134, 2007 | 187 | 2007 |