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Michael Howell
Michael Howell
Unknown affiliation
Verified email at crick.ac.uk
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Cited by
Year
Replication stress links structural and numerical cancer chromosomal instability
RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ...
Nature 494 (7438), 492-496, 2013
9012013
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
ZT Schug, B Peck, DT Jones, Q Zhang, S Grosskurth, IS Alam, ...
Cancer cell 27 (1), 57-71, 2015
7022015
Neutralising antibody activity against SARS-CoV-2 VOCs B. 1.617. 2 and B. 1.351 by BNT162b2 vaccination
EC Wall, M Wu, R Harvey, G Kelly, S Warchal, C Sawyer, R Daniels, ...
The Lancet 397 (10292), 2331-2333, 2021
5862021
Chromosomal instability confers intrinsic multidrug resistance
AJX Lee, D Endesfelder, AJ Rowan, A Walther, NJ Birkbak, PA Futreal, ...
Cancer research 71 (5), 1858-1870, 2011
5102011
The novel mechanism of initiation of picornavirus RNA translation
RJ Jackson, MT Howell, A Kaminski
Trends in biochemical sciences 15 (12), 477-483, 1990
5091990
Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif
S Germain, M Howell, GM Esslemont, CS Hill
Genes & Development 14 (4), 435-451, 2000
3502000
Chromosomal instability determines taxane response
C Swanton, B Nicke, M Schuett, AC Eklund, C Ng, Q Li, T Hardcastle, ...
Proceedings of the National Academy of Sciences 106 (21), 8671-8676, 2009
3112009
The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma
H Miess, B Dankworth, AM Gouw, M Rosenfeldt, W Schmitz, M Jiang, ...
Oncogene 37 (40), 5435-5450, 2018
2752018
T cell repertoire following autologous stem cell transplantation for multiple sclerosis
PA Muraro, H Robins, S Malhotra, M Howell, D Phippard, C Desmarais, ...
The Journal of clinical investigation 124 (3), 1168-1172, 2014
2692014
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers
CF Houlihan, N Vora, T Byrne, D Lewer, G Kelly, J Heaney, S Gandhi, ...
The Lancet 396 (10246), e6-e7, 2020
2472020
Initiation of encephalomyocarditis virus RNA translation: the authentic initiation site is not selected by a scanning mechanism.
A Kaminski, MT Howell, RJ Jackson
The EMBO journal 9 (11), 3753-3759, 1990
2421990
Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 as an important regulator of prostate cancer cell survival
S Ros, CR Santos, S Moco, F Baenke, G Kelly, M Howell, N Zamboni, ...
Cancer discovery 2 (4), 328-343, 2012
2232012
Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration
AL Nishimura, V Župunski, C Troakes, C Kathe, P Fratta, M Howell, ...
Brain 133 (6), 1763-1771, 2010
2192010
Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments
B Peck, ZT Schug, Q Zhang, B Dankworth, DT Jones, E Smethurst, ...
Cancer & metabolism 4, 1-18, 2016
2172016
Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies
M Steckel, M Molina-Arcas, B Weigelt, M Marani, PH Warne, H Kuznetsov, ...
Cell research 22 (8), 1227-1245, 2012
1982012
Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation
L Levy, M Howell, D Das, S Harkin, V Episkopou, CS Hill
Molecular and Cellular Biology 27 (17), 6068-6083, 2007
1942007
UV irradiation induces a non-coding RNA that functionally opposes the protein encoded by the same gene
L Williamson, M Saponaro, S Boeing, P East, R Mitter, T Kantidakis, ...
Cell 168 (5), 843-855. e13, 2017
1912017
Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription
S Ross, E Cheung, TG Petrakis, M Howell, WL Kraus, CS Hill
The EMBO journal 25 (19), 4490-4502, 2006
1842006
The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation
A Borman, MT Howell, JG Patton, RJ Jackson
Journal of General Virology 74 (9), 1775-1788, 1993
1831993
Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial
MR Rigby, LA DiMeglio, MS Rendell, EI Felner, JM Dostou, SE Gitelman, ...
The lancet Diabetes & endocrinology 1 (4), 284-294, 2013
1822013
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