Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal KM Storek, MR Auerbach, H Shi, NK Garcia, D Sun, NN Nickerson, R Vij, ... Proceedings of the National Academy of Sciences 115 (14), 3692-3697, 2018 | 158 | 2018 |
Structure of the essential inner membrane lipopolysaccharide–PbgA complex T Clairfeuille, KR Buchholz, Q Li, E Verschueren, P Liu, D Sangaraju, ... Nature 584 (7821), 479-483, 2020 | 73 | 2020 |
Sorting of an integral outer membrane protein via the lipoprotein‐specific Lol pathway and a dedicated lipoprotein pilotin S Collin, I Guilvout, NN Nickerson, AP Pugsley Molecular microbiology 80 (3), 655-665, 2011 | 72 | 2011 |
Activation of the SspA serine protease zymogen of Staphylococcus aureus proceeds through unique variations of a trypsinogen-like mechanism and is dependent on both … NN Nickerson, L Prasad, L Jacob, LT Delbaere, MJ McGavin Journal of biological chemistry 282 (47), 34129-34138, 2007 | 68 | 2007 |
A novel inhibitor of the LolCDE ABC transporter essential for lipoprotein trafficking in Gram-negative bacteria NN Nickerson, CC Jao, Y Xu, J Quinn, E Skippington, MK Alexander, ... Antimicrobial agents and chemotherapy 62 (4), 10.1128/aac. 02151-17, 2018 | 64 | 2018 |
Disrupting gram-negative bacterial outer membrane biosynthesis through inhibition of the lipopolysaccharide transporter MsbA MK Alexander, A Miu, A Oh, M Reichelt, H Ho, C Chalouni, S Labadie, ... Antimicrobial Agents and Chemotherapy 62 (11), 10.1128/aac. 01142-18, 2018 | 61 | 2018 |
Rapid autocatalytic activation of the M4 metalloprotease aureolysin is controlled by a conserved N‐terminal fungalysin‐thermolysin‐propeptide domain NN Nickerson, V Joag, MJ McGavin Molecular microbiology 69 (6), 1530-1543, 2008 | 59 | 2008 |
Evolutionary blueprint for host- and niche-adaptation in Staphylococcus aureus clonal complex CC30 MJ McGavin, B Arsic, NN Nickerson Frontiers in cellular and infection microbiology 2, 48, 2012 | 52 | 2012 |
Trapped translocation intermediates establish the route for export of capsular polysaccharides across Escherichia coli outer membranes NN Nickerson, IL Mainprize, L Hampton, ML Jones, JH Naismith, ... Proceedings of the National Academy of Sciences 111 (22), 8203-8208, 2014 | 50 | 2014 |
Outer membrane targeting of Pseudomonas aeruginosa proteins shows variable dependence on the components of Bam and Lol machineries HH Hoang, NN Nickerson, VT Lee, A Kazimirova, M Chami, AP Pugsley, ... MBio 2 (6), 10.1128/mbio. 00246-11, 2011 | 47 | 2011 |
Pilotin–secretin recognition in the type II secretion system of Klebsiella oxytoca T Tosi, NN Nickerson, L Mollica, MR Jensen, M Blackledge, B Baron, ... Molecular microbiology 82 (6), 1422-1432, 2011 | 41 | 2011 |
Outer Membrane Targeting of Secretin PulD Protein Relies on Disordered Domain Recognition by a Dedicated Chaperone*♦ NN Nickerson, T Tosi, A Dessen, B Baron, B Raynal, P England, ... Journal of Biological Chemistry 286 (45), 38833-38843, 2011 | 41 | 2011 |
Comparison of Staphopain A (ScpA) and B (SspB) precursor activation mechanisms reveals unique secretion kinetics of proSspB (Staphopain B), and a different interaction with its … N Nickerson, J Ip, DT Passos, MJ McGavin Molecular microbiology 75 (1), 161-177, 2010 | 41 | 2010 |
Multimerization-defective variants of dodecameric secretin PulD I Guilvout, NN Nickerson, M Chami, AP Pugsley Research in microbiology 162 (2), 180-190, 2011 | 36 | 2011 |
Peptidoglycan association of murein lipoprotein is required for KpsD-dependent group 2 capsular polysaccharide expression and serum resistance in a uropathogenic Escherichia … J Diao, C Bouwman, D Yan, J Kang, AK Katakam, P Liu, H Pantua, ... MBio 8 (3), 10.1128/mbio. 00603-17, 2017 | 34 | 2017 |
Structural and functional variation in outer membrane polysaccharide export (OPX) proteins from the two major capsule assembly pathways present in Escherichia coli C Sande, C Bouwman, E Kell, NN Nickerson, SB Kapadia, C Whitfield Journal of Bacteriology 201 (14), 10.1128/jb. 00213-19, 2019 | 18 | 2019 |
A single amino acid substitution changes the self-assembly status of a type IV piliation secretin NN Nickerson, SS Abby, EPC Rocha, M Chami, AP Pugsley Journal of bacteriology 194 (18), 4951-4958, 2012 | 17 | 2012 |
Inhibition of Escherichia coli lipoprotein diacylglyceryl transferase is insensitive to resistance caused by deletion of Braun’s lipoprotein J Diao, R Komura, T Sano, H Pantua, KM Storek, H Inaba, H Ogawa, ... Journal of Bacteriology 203 (13), 10.1128/jb. 00149-21, 2021 | 16 | 2021 |
Lipids assist the membrane insertion of a BAM-independent outer membrane protein GHM Huysmans, I Guilvout, M Chami, NN Nickerson, AP Pugsley Scientific reports 5 (1), 15068, 2015 | 15 | 2015 |
Genetic, biochemical, and structural analyses of bacterial surface polysaccharides CA Cooper, IL Mainprize, NN Nickerson Prokaryotic Systems Biology, 295-315, 2015 | 6 | 2015 |