Követés
Joe A Kaczmarski
Joe A Kaczmarski
E-mail megerősítve itt: anu.edu.au
Cím
Hivatkozott rá
Hivatkozott rá
Év
Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein
BE Clifton, JA Kaczmarski, PD Carr, ML Gerth, N Tokuriki, CJ Jackson
Nature chemical biology 14 (6), 542-547, 2018
922018
Ancestral sequence reconstruction for protein engineers
MA Spence, JA Kaczmarski, JW Saunders, CJ Jackson
Current opinion in structural biology 69, 131-141, 2021
812021
Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity
T Izoré, YT Candace Ho, JA Kaczmarski, A Gavriilidou, KH Chow, ...
Nature communications 12 (1), 2511, 2021
592021
Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics
A Greule, T Izoré, D Iftime, J Tailhades, M Schoppet, Y Zhao, M Peschke, ...
Nature Communications 10 (1), 2613, 2019
492019
T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein
CR Fisher, HJ Sutton, JA Kaczmarski, HA McNamara, B Clifton, J Mitchell, ...
PLoS pathogens 13 (7), e1006469, 2017
492017
Investigating the size and dynamics of voltage-gated sodium channel fenestrations: A molecular dynamics study
JA Kaczmarski, B Corry
Channels 8 (3), 264-277, 2014
472014
Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme
JA Kaczmarski, MC Mahawaththa, A Feintuch, BE Clifton, LA Adams, ...
Nature communications 11 (1), 5945, 2020
372020
Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes
D Chatterjee, FJ Lewis, HJ Sutton, JA Kaczmarski, X Gao, Y Cai, ...
Cell Reports 35 (2), 2021
312021
Structural and evolutionary approaches to the design and optimization of fluorescence-based small molecule biosensors
JA Kaczmarski, JA Mitchell, MA Spence, V Vongsouthi, CJ Jackson
Current Opinion in Structural Biology 57, 31-38, 2019
302019
Structural Basis for the Allosteric Regulation of the SbtA Bicarbonate Transporter by the PII-like Protein, SbtB, from Cyanobium sp. PCC7001
JA Kaczmarski, NS Hong, B Mukherjee, LT Wey, L Rourke, B Förster, ...
Biochemistry 58 (50), 5030-5039, 2019
292019
Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of Ideonella sakaiensis PETase and Variants with Improved Stability …
Y Joho, V Vongsouthi, MA Spence, J Ton, C Gomez, LL Tan, ...
Biochemistry 62 (2), 437-450, 2022
282022
Drosophila melanogaster nonribosomal peptide synthetase Ebony encodes an atypical condensation domain
T Izoré, J Tailhades, MH Hansen, JA Kaczmarski, CJ Jackson, MJ Cryle
Proceedings of the National Academy of Sciences 116 (8), 2913-2918, 2019
242019
Potent cyclic peptide inhibitors of FXIIa discovered by mRNA display with genetic code reprogramming
DJ Ford, NM Duggan, SE Fry, J Ripoll-Rozada, SM Agten, W Liu, ...
Journal of Medicinal Chemistry 64 (11), 7853-7876, 2021
182021
Regulatory adenylnucleotide-mediated binding of the PII-like protein SbtB to the cyanobacterial bicarbonate transporter SbtA is controlled by the cellular energy state
B Förster, B Mukherjee, L Rourke, JA Kaczmarski, CJ Jackson, GD Price
bioRxiv, 2021
7*2021
Exploring performance parameters of artificial allosteric protein switches
CE Ayva, MM Fiorito, Z Guo, S Edwardraja, JA Kaczmarski, D Gagoski, ...
Journal of Molecular Biology 434 (17), 167678, 2022
52022
The role of oligomerization in the optimization of cyclohexadienyl dehydratase conformational dynamics and catalytic activity
NJ East, BE Clifton, CJ Jackson, JA Kaczmarski
Protein Science 31 (12), e4510, 2022
42022
P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate
S Zhang, L Zhang, A Greule, J Tailhades, E Marschall, P Prasongpholchai, ...
Acta Pharmaceutica Sinica B 13 (8), 3561-3574, 2023
12023
Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin
YT Ho, T Izoré, JA Kaczmarski, E Marschall, MS Ratnayake, J Tailhades, ...
Frontiers in Catalysis 3, 1184959, 2023
12023
Leveraging ancestral sequence reconstruction for protein representation learning
DM Matthews, MA Spence, AC Mater, J Nichols, SB Pulsford, M Sandhu, ...
bioRxiv, 2023.12. 20.572683, 2023
12023
Identification and characterization of a bacterial periplasmic solute binding protein that binds L-amino acid amides.
OB Smith, RL Frkic, MG Rahman, CJJ Jackson, JA Kaczmarski
bioRxiv, 2024.02. 22.581678, 2024
2024
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