| Polymorphisms at PRSS1–PRSS2 and CLDN2–MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study MH Derikx, P Kovacs, M Scholz, E Masson, JM Chen, C Ruffert, P Lichtner, ... Gut 64 (9), 1426-1433, 2015 | 132 | 2015 |
| Valproate ameliorates the survival and the motor performance in a transgenic mouse model of Huntington's disease D Zádori, A Geisz, E Vámos, L Vécsei, P Klivényi Pharmacology Biochemistry and Behavior 94 (1), 148-153, 2009 | 102 | 2009 |
| Trypsin reduces pancreatic ductal bicarbonate secretion by inhibiting CFTR Cl− channels and luminal anion exchangers P Pallagi, V Venglovecz, Z Rakonczay Jr, K Borka, A Korompay, B Ózsvári, ... Gastroenterology 141 (6), 2228-2239. e6, 2011 | 99 | 2011 |
| A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation A Geisz, M Sahin-Tóth Nature communications 9 (1), 5033, 2018 | 77 | 2018 |
| NHE1 activity contributes to migration and is necessary for proliferation of human gastric myofibroblasts M Czepán, Z Rakonczay, A Varró, I Steele, R Dimaline, N Lertkowit, ... Pflügers Archiv-European Journal of Physiology 463, 459-475, 2012 | 36 | 2012 |
| Na+/Ca2+ exchangers regulate the migration and proliferation of human gastric myofibroblasts LV Kemény, A Schnúr, M Czepán, Z Rakonczay Jr, E Gál, J Lonovics, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 305 (8 …, 2013 | 34 | 2013 |
| Robust autoactivation, chymotrypsin C independence and diminished secretion define a subset of hereditary pancreatitis‐associated cationic trypsinogen mutants A Geisz, P Hegyi, M Sahin‐Tóth The FEBS journal 280 (12), 2888-2899, 2013 | 32 | 2013 |
| No significant enrichment of rare functionally defective CPA1 variants in a large Chinese idiopathic chronic pancreatitis cohort H Wu, DZ Zhou, D Berki, A Geisz, WB Zou, XT Sun, LH Hu, ZH Zhao, ... Human mutation 38 (8), 959-963, 2017 | 28 | 2017 |
| Intragenic duplication: a novel mutational mechanism in hereditary pancreatitis MT Joergensen, A Geisz, K Brusgaard, OBS de Muckadell, P Hegyi, ... Pancreas 40 (4), 540-546, 2011 | 26 | 2011 |
| Variants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis E Nakano, A Geisz, A Masamune, T Niihori, S Hamada, K Kume, Y Kakuta, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 309 (8 …, 2015 | 21 | 2015 |
| Natural single-nucleotide deletion in chymotrypsinogen C gene increases severity of secretagogue-induced pancreatitis in C57BL/6 mice A Geisz, Z Jancsó, BC Németh, E Hegyi, M Sahin-Tóth JCI insight 4 (14), 2019 | 20 | 2019 |
| Functional significance of SPINK1 promoter variants in chronic pancreatitis MHM Derikx, A Geisz, É Kereszturi, M Sahin-Tóth American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (9 …, 2015 | 17 | 2015 |
| Ethanol feeding accelerates pancreatitis progression in CPA1 N256K mutant mice A Orekhova, A Geisz, M Sahin-Tóth American Journal of Physiology-Gastrointestinal and Liver Physiology 318 (4 …, 2020 | 14 | 2020 |
| SPINK1 promoter variants in chronic pancreatitis E Hegyi, A Geisz, M Sahin-Tóth, MHM Derikx, BC Németh, A Balázs, ... Pancreas 45 (1), 148-153, 2016 | 14 | 2016 |
| Integrated physiology of the exocrine and endocrine compartments in pancreatic diseases: Workshop proceedings TL Mastracci, M Apte, LT Amundadottir, A Alvarsson, S Artandi, MD Bellin, ... Diabetes 72 (4), 433-448, 2023 | 11 | 2023 |
| Arg236 in human chymotrypsin B2 (CTRB2) is a key determinant of high enzyme activity, trypsinogen degradation capacity, and protection against pancreatitis BZ Németh, A Demcsák, A Micsonai, B Kiss, G Schlosser, A Geisz, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1870 (9), 140831, 2022 | 10 | 2022 |
| Misfolding-induced chronic pancreatitis in CPA1 N256K mutant mice is unaffected by global deletion of Ddit3/Chop BC Németh, A Demcsák, A Geisz, M Sahin-Tóth Scientific Reports 12 (1), 6357, 2022 | 9 | 2022 |
| Sentinel acute pancreatitis event increases severity of subsequent episodes in mice A Geisz, M Sahin-Tóth Gastroenterology 161 (5), 1692-1694, 2021 | 9 | 2021 |
| Engineering mouse cationic trypsinogen for rapid and selective activation by cathepsin B A Demcsák, A Geisz, M Sahin-Tóth Scientific reports 9 (1), 9188, 2019 | 9 | 2019 |
| Trypsin activity in secretagogue-induced murine pancreatitis is solely elicited by cathepsin B and does not mediate key pathologic responses A Geisz, T Tran, A Orekhova, M Sahin-Tóth Gastroenterology 164 (4), 684-687. e4, 2023 | 7 | 2023 |
Miklos Sahin-TothProfessor of Surgery, UCLAVerified email at mednet.ucla.edu
