| Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man DK Walker Xenobiotica 29 (3), 297-310, 1999 | 486 | 1999 |
| A holistic strategy for characterizing the safety of metabolites through drug discovery and development D Walker, J Brady, D Dalvie, J Davis, M Dowty, JN Duncan, A Nedderman, ... Chemical research in toxicology 22 (10), 1653-1662, 2009 | 75 | 2009 |
| Can density functional theory (DFT) be used as an aid to a deeper understanding of tandem mass spectrometric fragmentation pathways? A Alex, S Harvey, T Parsons, FS Pullen, P Wright, JA Riley Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2009 | 70 | 2009 |
| How Useful Is Molecular Modelling in Combination with Ion Mobility Mass Spectrometry for ‘small Molecule’ Ion Mobility Collision Cross-Sections Cris Lapthorn, Frank Pullen, Babur Chowdhry, Patricia Wright, George Perkins ... Analyst, 2015 | 66 | 2015 |
| Direct analysis of crude plasma samples by turbulent flow chromatography/tandem mass spectrometry C Chassaing, J Luckwell, P Macrae, K Saunders, P Wright, R Venn Chromatographia 53, 122-130, 2000 | 47 | 2000 |
| Using density functional theory to rationalise the mass spectral fragmentation of maraviroc and its metabolites P Wright, A Alex, T Nyaruwata, T Parsons, F Pullen Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2010 | 45 | 2010 |
| SAR of a series of inhaled A2A agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data SJ Mantell, PT Stephenson, SM Monaghan, GN Maw, MA Trevethick, ... Bioorganic & medicinal chemistry letters 19 (15), 4471-4475, 2009 | 36 | 2009 |
| Metabolite identification by mass spectrometry: forty years of evolution P Wright Xenobiotica 41 (8), 670-686, 2011 | 35 | 2011 |
| Predicting collision-induced dissociation spectra: Semi-empirical calculations as a rapid and effective tool in software-aided mass spectral interpretation P Wright, A Alex, F Pullen Rapid Communications in Mass Spectrometry 28 (10), 1127-1143, 2014 | 27 | 2014 |
| Metabolite quantitation: detector technology and MIST implications P Wright, Z Miao, B Shilliday Bioanalysis 1 (4), 831-845, 2009 | 21 | 2009 |
| Predicting collision‐induced dissociation mass spectra: understanding the role of the mobile proton in small molecule fragmentation P Wright, A Alex, F Pullen Rapid Communications in Mass Spectrometry 30 (9), 1163-1175, 2016 | 19 | 2016 |
| Characterisation of sulphoxides by atmospheric pressure ionisation mass spectrometry P Wright, A Alex, D Gibson, R Jones, P Macrae Rapid communications in mass spectrometry 19 (14), 2005 | 17 | 2005 |
| Understanding collision-induced dissociation of dofetilide: a case study in the application of density functional theory as an aid to mass spectral interpretation P Wright, A Alex, S Harvey, T Parsons, F Pullen Analyst 138 (22), 6869-6880, 2013 | 16 | 2013 |
| Looking back through the MIST: a perspective of evolving strategies and key focus areas for metabolite safety analysis ANR Nedderman, P Wright Bioanalysis 2 (7), 1235-1248, 2010 | 15 | 2010 |
| Evolution of an open‐access quantitative bioanalytical mass spectrometry service in a drug discovery environment P Wright, C Chassaing, N Cussans, D Gibson, C Green, M Gleave, ... Biomedical Chromatography 20 (6‐7), 585-596, 2006 | 13 | 2006 |
| Pharmacokinetics and metabolism of a selective PDE5 inhibitor (UK-343,664) in rat and dog DK Walker, KC Beaumont, P Comby, KM Evans, JI Gedge, RC Halliday, ... Xenobiotica 31 (8-9), 651-664, 2001 | 11 | 2001 |
| High‐throughput approaches towards the definitive identification of pharmaceutical drug metabolites. 2. An example of how unexpected dissociation behaviour could preclude … SW Holman, P Wright, GJ Langley Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2009 | 10 | 2009 |
| A Rapid Methodology for the Characterization of Dialkyl Tertiary Amine-N-Oxide Metabolites Using Structurally Dependent Dissociation Pathways and … SW Holman, P Wright, GJ Langley Analytical chemistry 82 (6), 2347-2354, 2010 | 8 | 2010 |
| Chlorpromazine inhibition of melatonin metabolism by normal and induced rat liver microsomes C Beedham, JA Smith, D Steele, PA Wright European journal of drug metabolism and pharmacokinetics 12, 299-302, 1987 | 8 | 1987 |
| Evidence for site‐specific intra‐ionic hydrogen/deuterium exchange in the low‐energy collision‐induced dissociation product ion spectra of protonated small molecules generated … SW Holman, P Wright, NJ Wells, GJ Langley Journal of Mass Spectrometry 45 (4), 347-357, 2010 | 5 | 2010 |
