Követés
Kurt De Vos
Kurt De Vos
E-mail megerősítve itt: sheffield.ac.uk
Cím
Hivatkozott rá
Hivatkozott rá
Év
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
C Vance, B Rogelj, T Hortobágyi, KJ De Vos, AL Nishimura, J Sreedharan, ...
Science 323 (5918), 1208-1211, 2009
29752009
Role of axonal transport in neurodegenerative diseases
KJ De Vos, AJ Grierson, S Ackerley, CCJ Miller
Annu. Rev. Neurosci. 31, 151-173, 2008
8722008
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity.
V Goossens, J Grooten, K De Vos, W Fiers
Proceedings of the National Academy of Sciences 92 (18), 8115-8119, 1995
7481995
ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43
R Stoica, KJ De Vos, S Paillusson, S Mueller, RM Sancho, KF Lau, ...
Nature communications 5 (1), 3996, 2014
5922014
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
KJ De Vos, GM Morotz, R Stoica, EL Tudor, KF Lau, S Ackerley, A Warley, ...
Human molecular genetics 21 (6), 1299-1311, 2012
5082012
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ...
Human molecular genetics 16 (22), 2720-2728, 2007
4852007
The role of mitochondria in amyotrophic lateral sclerosis
EF Smith, PJ Shaw, KJ De Vos
Neuroscience letters 710, 132933, 2019
4842019
The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagy
CP Webster, EF Smith, CS Bauer, A Moller, GM Hautbergue, L Ferraiuolo, ...
The EMBO journal 35 (15), 1656-1676, 2016
4282016
Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity
K Vancompernolle, F Van Herreweghe, G Pynaert, M Van de Craen, ...
FEBS letters 438 (3), 150-158, 1998
3931998
Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission
KJ De Vos, VJ Allan, AJ Grierson, MP Sheetz
Current Biology 15 (7), 678-683, 2005
3872005
Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations
VK Godena, N Brookes-Hocking, A Moller, G Shaw, M Oswald, ...
Nature communications 5 (1), 5245, 2014
2892014
RPTP-α acts as a transducer of mechanical force on αv3-integrin–cytoskeleton linkages
G Von Wichert, G Jiang, A Kostic, K De Vos, J Sap, MP Sheetz
The Journal of cell biology 161 (1), 143-153, 2003
2632003
ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP 51 interaction and ER–mitochondria associations
R Stoica, S Paillusson, P Gomez‐Suaga, JC Mitchell, DHW Lau, EH Gray, ...
EMBO reports 17 (9), 1326-1342, 2016
2532016
Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?
KJ De Vos, M Hafezparast
Neurobiology of disease 105, 283-299, 2017
2372017
The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region
K De Vos, V Goossens, E Boone, D Vercammen, K Vancompernolle, ...
Journal of Biological Chemistry 273 (16), 9673-9680, 1998
2011998
C9orf72 expansion disrupts ATM-mediated chromosomal break repair
C Walker, S Herranz-Martin, E Karyka, C Liao, K Lewis, W Elsayed, ...
Nature neuroscience 20 (9), 1225-1235, 2017
1742017
Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration
TM Woodruff, JW Crane, LM Proctor, KM Buller, AB Shek, K De Vos, ...
The FASEB Journal 20 (9), 1407-1417, 2006
1622006
Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
GM Morotz, KJ De Vos, A Vagnoni, S Ackerley, CE Shaw, CCJ Miller
Human molecular genetics 21 (9), 1979-1988, 2012
1552012
Direct evidence for axonal transport defects in a novel mouse model of mutant spastin‐induced hereditary spastic paraplegia (HSP) and human HSP patients
PR Kasher, KJ De Vos, SB Wharton, C Manser, EJ Bennett, M Bingley, ...
Journal of neurochemistry 110 (1), 34-44, 2009
1482009
Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria
K De Vos, F Severin, F Van Herreweghe, K Vancompernolle, V Goossens, ...
The Journal of cell biology 149 (6), 1207-1214, 2000
1452000
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