Kurt De Vos
Kurt De Vos
E-mail megerősítve itt: sheffield.ac.uk
Hivatkozott rá
Hivatkozott rá
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
C Vance, B Rogelj, T Hortobágyi, KJ De Vos, AL Nishimura, J Sreedharan, ...
Science 323 (5918), 1208-1211, 2009
Role of axonal transport in neurodegenerative diseases
KJ De Vos, AJ Grierson, S Ackerley, CCJ Miller
Annu. Rev. Neurosci. 31, 151-173, 2008
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity.
V Goossens, J Grooten, K De Vos, W Fiers
Proceedings of the National Academy of Sciences 92 (18), 8115-8119, 1995
ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43
R Stoica, KJ De Vos, S Paillusson, S Mueller, RM Sancho, KF Lau, ...
Nature communications 5 (1), 3996, 2014
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
KJ De Vos, GM Morotz, R Stoica, EL Tudor, KF Lau, S Ackerley, A Warley, ...
Human molecular genetics 21 (6), 1299-1311, 2012
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ...
Human molecular genetics 16 (22), 2720-2728, 2007
The role of mitochondria in amyotrophic lateral sclerosis
EF Smith, PJ Shaw, KJ De Vos
Neuroscience letters 710, 132933, 2019
The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagy
CP Webster, EF Smith, CS Bauer, A Moller, GM Hautbergue, L Ferraiuolo, ...
The EMBO journal 35 (15), 1656-1676, 2016
Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity
K Vancompernolle, F Van Herreweghe, G Pynaert, M Van de Craen, ...
FEBS letters 438 (3), 150-158, 1998
Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission
KJ De Vos, VJ Allan, AJ Grierson, MP Sheetz
Current Biology 15 (7), 678-683, 2005
Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations
VK Godena, N Brookes-Hocking, A Moller, G Shaw, M Oswald, ...
Nature communications 5 (1), 5245, 2014
RPTP-α acts as a transducer of mechanical force on αv3-integrin–cytoskeleton linkages
G Von Wichert, G Jiang, A Kostic, K De Vos, J Sap, MP Sheetz
The Journal of cell biology 161 (1), 143-153, 2003
ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP 51 interaction and ER–mitochondria associations
R Stoica, S Paillusson, P Gomez‐Suaga, JC Mitchell, DHW Lau, EH Gray, ...
EMBO reports 17 (9), 1326-1342, 2016
Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?
KJ De Vos, M Hafezparast
Neurobiology of disease 105, 283-299, 2017
The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region
K De Vos, V Goossens, E Boone, D Vercammen, K Vancompernolle, ...
Journal of Biological Chemistry 273 (16), 9673-9680, 1998
C9orf72 expansion disrupts ATM-mediated chromosomal break repair
C Walker, S Herranz-Martin, E Karyka, C Liao, K Lewis, W Elsayed, ...
Nature neuroscience 20 (9), 1225-1235, 2017
Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration
TM Woodruff, JW Crane, LM Proctor, KM Buller, AB Shek, K De Vos, ...
The FASEB Journal 20 (9), 1407-1417, 2006
Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
GM Morotz, KJ De Vos, A Vagnoni, S Ackerley, CE Shaw, CCJ Miller
Human molecular genetics 21 (9), 1979-1988, 2012
Direct evidence for axonal transport defects in a novel mouse model of mutant spastin‐induced hereditary spastic paraplegia (HSP) and human HSP patients
PR Kasher, KJ De Vos, SB Wharton, C Manser, EJ Bennett, M Bingley, ...
Journal of neurochemistry 110 (1), 34-44, 2009
Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria
K De Vos, F Severin, F Van Herreweghe, K Vancompernolle, V Goossens, ...
The Journal of cell biology 149 (6), 1207-1214, 2000
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