Követés
Stephen Caddick
Stephen Caddick
Professor of Organic Chemistry and Chemical Biology, UCL
E-mail megerősítve itt: ucl.ac.uk - Kezdőlap
Cím
Hivatkozott rá
Hivatkozott rá
Év
Microwave assisted organic reactions
S Caddick
Tetrahedron 51 (38), 10403-10432, 1995
22521995
Microwave enhanced synthesis
S Caddick, R Fitzmaurice
Tetrahedron 65 (17), 3325-3355, 2009
4932009
Protein modification, bioconjugation, and disulfide bridging using bromomaleimides
MEB Smith, FF Schumacher, CP Ryan, LM Tedaldi, D Papaioannou, ...
Journal of the American Chemical Society 132 (6), 1960-1965, 2010
4352010
Recent advances in the construction of antibody–drug conjugates
V Chudasama, A Maruani, S Caddick
Nature chemistry 8 (2), 114-119, 2016
3632016
Dynamic resolutions in asymmetric synthesis
S Caddick, K Jenkins
Chemical Society Reviews 25 (6), 447-456, 1996
2821996
A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy
A Maruani, MEB Smith, E Miranda, KA Chester, V Chudasama, S Caddick
Nature communications 6 (1), 6645, 2015
2612015
Direct synthesis of sulfonamides and activated sulfonate esters from sulfonic acids
S Caddick, JD Wilden, DB Judd
Journal of the American Chemical Society 126 (4), 1024-1025, 2004
2262004
A generic approach for the catalytic reduction of nitriles
S Caddick, DB Judd, AK de K Lewis, MT Reich, MRV Williams
Tetrahedron 59 (29), 5417-5423, 2003
2002003
Hydroacylation of α, β-unsaturated esters via aerobic C–H activation
V Chudasama, RJ Fitzmaurice, S Caddick
Nature chemistry 2 (7), 592-596, 2010
1922010
Unusual reactivity of a nickel N-heterocyclic carbene complex: tert-butyl group cleavage and silicone grease activation
S Caddick, FGN Cloke, PB Hitchcock, AKK Lewis, AKDEK LEWIS
Angewandte Chemie (International ed.) 43 (43), 5824-5827, 2004
1902004
In situ maleimide bridging of disulfides and a new approach to protein PEGylation
FF Schumacher, M Nobles, CP Ryan, MEB Smith, A Tinker, S Caddick, ...
Bioconjugate chemistry 22 (2), 132-136, 2011
1802011
Next generation maleimides enable the controlled assembly of antibody–drug conjugates via native disulfide bond bridging
FF Schumacher, JPM Nunes, A Maruani, V Chudasama, MEB Smith, ...
Organic & biomolecular chemistry 12 (37), 7261-7269, 2014
1782014
Polymeric dibromomaleimides as extremely efficient disulfide bridging bioconjugation and pegylation agents
MW Jones, RA Strickland, FF Schumacher, S Caddick, JR Baker, ...
Journal of the American Chemical Society 134 (3), 1847-1852, 2012
1762012
Suzuki–Miyaura cross-coupling of aryl and alkyl halides using palladium/imidazolium salt protocols
K Arentsen, S Caddick, FGN Cloke, AP Herring, PB Hitchcock
Tetrahedron letters 45 (17), 3511-3515, 2004
1652004
Synthetic, structural, and mechanistic studies on the oxidative addition of aromatic chlorides to a palladium (N-heterocyclic carbene) complex: relevance to catalytic amination
AKK Lewis, S Caddick, FGN Cloke, NC Billingham, PB Hitchcock, ...
Journal of the American Chemical Society 125 (33), 10066-10073, 2003
1602003
Tuning the Reactivity of Dirhodium (II) Complexes with Axial N‐Heterocyclic Carbene Ligands: The Arylation of Aldehydes
PMP Gois, AF Trindade, LF Veiros, V Andre, MT Duarte, CAM Afonso, ...
Angewandte Chemie International Edition 46 (30), 5750-5753, 2007
1392007
Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody–drug conjugate (ADC)
JPM Nunes, M Morais, V Vassileva, E Robinson, VS Rajkumar, ...
Chemical communications 51 (53), 10624-10627, 2015
1342015
Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis
CP Ryan, MEB Smith, FF Schumacher, D Grohmann, D Papaioannou, ...
Chemical communications 47 (19), 5452-5454, 2011
1262011
Inhibition of HIV‐1 Replication by Isoxazolidine and Isoxazole Sulfonamides
B Loh, L Vozzolo, BJ Mok, CC Lee, RJ Fitzmaurice, S Caddick, A Fassati
Chemical Biology & Drug Design 75 (5), 461-474, 2010
1242010
Bromopyridazinedione-mediated protein and peptide bioconjugation
V Chudasama, MEB Smith, FF Schumacher, D Papaioannou, G Waksman, ...
Chemical communications 47 (31), 8781-8783, 2011
1202011
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