Nick Le Brun
Nick Le Brun
Professor of Biological Chemistry
Verified email at - Homepage
Cited by
Cited by
Iron–Sulfur Clusters as Biological Sensors: The Chemistry of Reactions with Molecular Oxygen and Nitric Oxide
JC Crack, J Green, AJ Thomson, NE Le Brun
Accounts of Chemical Research, 2014
The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster
NP Tucker, MG Hicks, TA Clarke, JC Crack, G Chandra, NE Le Brun, ...
PloS one 3 (11), e3623, 2008
Bacterial sensors of oxygen
J Green, JC Crack, AJ Thomson, NE LeBrun
Current opinion in microbiology 12 (2), 145-151, 2009
Mechanistic Insight into the Nitrosylation of the [4Fe− 4S] Cluster of WhiB-like Proteins
JC Crack, LJ Smith, MR Stapleton, J Peck, NJ Watmough, MJ Buttner, ...
Journal of the American Chemical Society 133 (4), 1112-1121, 2011
Superoxide-mediated amplification of the oxygen-induced switch from [4Fe-4S] to [2Fe-2S] clusters in the transcriptional regulator FNR
JC Crack, J Green, MR Cheesman, NE Le Brun, AJ Thomson
Proceedings of the National Academy of Sciences 104 (7), 2092-2097, 2007
Mycobacterium tuberculosis WhiB1 is an essential DNA-binding protein with a nitric oxide-sensitive iron–sulfur cluster
LJ Smith, MR Stapleton, GJM Fullstone, JC Crack, AJ Thomson, ...
Biochemical Journal 432 (3), 417-427, 2010
There's NO stopping NsrR, a global regulator of the bacterial NO stress response
NP Tucker, NE Le Brun, R Dixon, MI Hutchings
Trends in microbiology 18 (4), 149-156, 2010
Iron core mineralisation in prokaryotic ferritins
NE Le Brun, A Crow, MEP Murphy, AG Mauk, GR Moore
Biochimica Et Biophysica Acta (BBA)-General Subjects 1800 (8), 732-744, 2010
The iron oxidation and hydrolysis chemistry of Escherichia coli bacterioferritin
X Yang, NE Le Brun, AJ Thomson, GR Moore, ND Chasteen
Biochemistry 39 (16), 4915-4923, 2000
Site-directed replacement of the coaxial heme ligands of bacterioferritin generates heme-free variants
SC Andrews, NE Le Brun, V Barynin, AJ Thomson, GR Moore, JR Guest, ...
Journal of Biological Chemistry 270 (40), 23268-23274, 1995
Genes required for cytochrome c synthesis inBacillus subtilis
NE Le Brun, J Bengtsson, L Hederstedt
Molecular microbiology 36 (3), 638-650, 2000
Formation of protein-coated iron minerals
A Lewin, GR Moore, NE Le Brun
Dalton transactions, 3597-3610, 2005
Reversible cycling between cysteine persulfide-ligated [2Fe-2S] and cysteine-ligated [4Fe-4S] clusters in the FNR regulatory protein
B Zhang, JC Crack, S Subramanian, J Green, AJ Thomson, NE Le Brun, ...
Proceedings of the National Academy of Sciences 109 (39), 15734-15739, 2012
Ferritins: furnishing proteins with iron
JM Bradley, NE Le Brun, GR Moore
JBIC Journal of Biological Inorganic Chemistry 21, 13-28, 2016
CopZ from Bacillus subtilis interacts in vivo with a copper exporting CPx‐type ATPase CopA
DS Radford, MA Kihlken, GPM Borrelly, CR Harwood, NE Brun, JS Cavet
FEMS microbiology letters 220 (1), 105-112, 2003
Iron–sulfur cluster sensor-regulators
JC Crack, J Green, AJ Thomson, NE Le Brun
Current opinion in chemical biology 16 (1-2), 35-44, 2012
Structural basis for iron mineralization by bacterioferritin
A Crow, TL Lawson, A Lewin, GR Moore, NEL Brun
Journal of the American Chemical Society 131 (19), 6808-6813, 2009
The O2 sensitivity of the transcription factor FNR is controlled by Ser24 modulating the kinetics of [4Fe-4S] to [2Fe-2S] conversion
AJ Jervis, JC Crack, G White, PJ Artymiuk, MR Cheesman, AJ Thomson, ...
Proceedings of the National Academy of Sciences 106 (12), 4659-4664, 2009
Bacillus subtilis ResA is a thiol-disulfide oxidoreductase involved in cytochrome c synthesis
LS Erlendsson, RM Acheson, L Hederstedt, NE Le Brun
Journal of Biological Chemistry 278 (20), 17852-17858, 2003
Iron Detoxification Properties of Escherichia coliBacterioferritin: ATTENUATION OF OXYRADICAL CHEMISTRY
F Bou-Abdallah, AC Lewin, NE Le Brun, GR Moore, ND Chasteen
Journal of Biological Chemistry 277 (40), 37064-37069, 2002
The system can't perform the operation now. Try again later.
Articles 1–20