| Single residue variation in skeletal muscle myosin enables direct and selective drug targeting for spasticity and muscle stiffness M Gyimesi, ÁI Horváth, D Túrós, SK Suthar, M Pénzes, C Kurdi, L Canon, ... Cell 183 (2), 335-346. e13, 2020 | 34 | 2020 |
| Direct myosin-2 inhibition enhances cerebral perfusion resulting in functional improvement after ischemic stroke M Pénzes, D Túrós, D Máthé, K Szigeti, N Hegedűs, AÁ Rauscher, P Tóth, ... Theranostics 10 (12), 5341, 2020 | 14 | 2020 |
| Post-reperfusion acute MR diffusion in stroke is a potential predictor for clinical outcome in rats SA Nagy, I Ivic, P Tóth, S Komoly, T Kiss, M Pénzes, A Málnási-Csizmadia, ... Scientific Reports 13 (1), 5598, 2023 | 1 | 2023 |
| Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms A Málnási-Csizmadia, M Gyimesi, A Szabó, P Hári, SS Kumar, M Kovács, ... US Patent App. 18/464,156, 2024 | | 2024 |
| Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms A Málnási-Csizmadia, M Gyimesi, A Szabó, P Hári, SS Kumar, M Kovács, ... US Patent 11,845,758, 2023 | | 2023 |
| Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms A Málnási-Csizmadia, M Gyimesi, A Szabó, P Hári, SS Kumar, M Kovács, ... US Patent 11,746,112, 2023 | | 2023 |
| Application of neural-network-based deep-learning analysis to reveal changes of the movement parameters in rat neuromuscular disorder models M Winternitz, M Gyimesi, AI Horvath, M Penzes, A Malnasi-Csizmadia Biophysical Journal 121 (3), 258a-259a, 2022 | | 2022 |
| First-in-class drug candidate (MPH-220) efficiently improves spastic gait disorders by selective inhibition of fast skeletal muscle myosin-2 M Gyimesi, AI Horvath, D Turos, SK Suthar, M Penzes, L Canon, C Kikuti, ... Biophysical Journal 121 (3), 291a, 2022 | | 2022 |
| Direct myosin-2 inhibition improves brain functions after ischemic stroke MI Pénzes | | 2022 |
| Direct Myosin-2 Inhibition Restores Cerebral Perfusion in Cortical and Subcortical Regions Resulting in Functional Improvement After Ischemic Stroke. M Penzes, D Turos, D Mathe, A Rauscher, P Toth, I Ivic, M Gyimesi, ... STROKE 52, 2021 | | 2021 |
| First-In-Class Anti-Spastic Drug Candidate (MPH-220) Efficiently Relaxes Spastic Muscles and Improves Motor Functions in Gait Disorder in Preclinical Studies. M Gyimesi, A Horvath, D Turos, M Penzes, C Kurdi, M Kovacs, ... STROKE 52, 2021 | | 2021 |
| Abstract P217: Direct Myosin-2 Inhibition Restores Cerebral Perfusion in Cortical and Subcortical Regions Resulting in Functional Improvement After Ischemic Stroke M Penzes, D Turos, D Mathe, A Rauscher, P Toth, I Ivic, M Gyimesi, ... Stroke 52 (Suppl_1), AP217-AP217, 2021 | | 2021 |
| Abstract P221: First-In-Class Anti-Spastic Drug Candidate (MPH-220) Efficiently Relaxes Spastic Muscles and Improves Motor Functions in Gait Disorder in Preclinical Studies M Gyimesi, A Horvath, D Turos, M Penzes, C Kurdi, M Kovacs, ... Stroke 52 (Suppl_1), AP221-AP221, 2021 | | 2021 |
| NEW-GENERATION ANTI-SPASTIC DRUG CANDIDATE (MPH-220) IMPROVES MOTOR FUNCTIONS OF SPASTIC RATS WITH BRAIN DAMAGE M Gyimesi, A Horvath, D Turos, M Penzes, C Kurdi, A Szabo, M Kovacs, ... INTERNATIONAL JOURNAL OF STROKE 15 (1_ SUPPL), 266-266, 2020 | | 2020 |
| DIRECT MYOSIN-2 INHIBITION RESTORES CEREBRAL PERFUSION RESULTING IN FUNCTIONAL IMPROVEMENT AFTER ISCHEMIC STROKE M Penzes, D Turos, D Mathe, A Rauscher, P Toth, I Ivic, A Dobolyi, ... INTERNATIONAL JOURNAL OF STROKE 15 (1_ SUPPL), 24-24, 2020 | | 2020 |
| Targeted Myosin-2 Inhibition Improves Brain Regeneration After Stroke by Relaxing Hypoxia-Induced Vasoconstriction in Capillaries M Penzes, D Turos, M Winternitz, I Ivic, P Toth, AÁ Rauscher, M Gyimesi, ... Biophysical Journal 118 (3), 434a-435a, 2020 | | 2020 |
