|Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data|
NT Gupta, JA Vander Heiden, M Uduman, D Gadala-Maria, G Yaari, ...
Bioinformatics 31 (20), 3356-3358, 2015
|B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes|
JNH Stern, G Yaari, JA Vander Heiden, G Church, WF Donahue, ...
Science translational medicine 6 (248), 248ra107-248ra107, 2014
|pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires|
JA Vander Heiden, G Yaari, M Uduman, JNH Stern, KC O’Connor, ...
Bioinformatics 30 (13), 1930-1932, 2014
|Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data|
G Yaari, JA Vander Heiden, M Uduman, D Gadala-Maria, N Gupta, ...
Frontiers in immunology 4, 358, 2013
|High-resolution antibody dynamics of vaccine-induced immune responses|
U Laserson, F Vigneault, D Gadala-Maria, G Yaari, M Uduman, ...
Proceedings of the National Academy of Sciences 111 (13), 4928-4933, 2014
|Salmonella infection drives promiscuous B cell activation followed by extrafollicular affinity maturation|
R Di Niro, SJ Lee, JA Vander Heiden, RA Elsner, N Trivedi, JM Bannock, ...
Immunity 43 (1), 120-131, 2015
|Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response|
BJ Laidlaw, Y Lu, RA Amezquita, JS Weinstein, JA Vander Heiden, ...
Science immunology 2 (16), eaan4767, 2017
|Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants|
R Malik, T Freilinger, BS Winsvold, V Anttila, J Vander Heiden, M Traylor, ...
Neurology 84 (21), 2132-2145, 2015
|Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-experienced cells|
F Rubelt, CR Bolen, HM McGuire, JAV Heiden, D Gadala-Maria, M Levin, ...
Nature communications 7 (1), 1-12, 2016
|Dysregulation of B cell repertoire formation in myasthenia gravis patients revealed through deep sequencing|
JA Vander Heiden, P Stathopoulos, JQ Zhou, L Chen, TJ Gilbert, ...
The Journal of Immunology 198 (4), 1460-1473, 2017
|Reproducibility and reuse of adaptive immune receptor repertoire data|
F Breden, ET Luning Prak, B Peters, F Rubelt, CA Schramm, CE Busse, ...
Frontiers in immunology 8, 1418, 2017
|Serum metabolomics reveals higher levels of polyunsaturated fatty acids in lepromatous leprosy: potential markers for susceptibility and pathogenesis|
R Al-Mubarak, J Vander Heiden, CD Broeckling, M Balagon, PJ Brennan, ...
PLoS neglected tropical diseases 5 (9), e1303, 2011
|Genetic analysis for a shared biological basis between migraine and coronary artery disease|
BS Winsvold, CP Nelson, R Malik, P Gormley, V Anttila, J Vander Heiden, ...
Neurology Genetics 1 (1), 2015
|A model of somatic hypermutation targeting in mice based on high-throughput Ig sequencing data|
A Cui, R Di Niro, JA Vander Heiden, AW Briggs, K Adams, T Gilbert, ...
The Journal of Immunology 197 (9), 3566-3574, 2016
|Identification of subject-specific immunoglobulin alleles from expressed repertoire sequencing data|
D Gadala-Maria, M Gidoni, S Marquez, JA Vander Heiden, JT Kos, ...
Frontiers in immunology 10, 129, 2019
|Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis|
YCB Wu, LK James, JA Vander Heiden, M Uduman, SR Durham, ...
Journal of allergy and clinical immunology 134 (3), 604-612, 2014
|Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production|
E Cotzomi, P Stathopoulos, CS Lee, AM Ritchie, JN Soltys, FR Delmotte, ...
Brain 142 (6), 1598-1615, 2019
|The Repertoire Dissimilarity Index as a method to compare lymphocyte receptor repertoires|
CR Bolen, F Rubelt, JA Vander Heiden, MM Davis
BMC bioinformatics 18 (1), 1-8, 2017
|The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales|
G Yaari, JIC Benichou, JA Vander Heiden, SH Kleinstein, Y Louzoun
Philosophical Transactions of the Royal Society B: Biological Sciences 370 …, 2015
|Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination|
KB Hoehn, JA Vander Heiden, JQ Zhou, G Lunter, OG Pybus, ...
Proceedings of the National Academy of Sciences 116 (45), 22664-22672, 2019