Követés
Prerna Malaney
Prerna Malaney
Assistant Professor, Dartmouth College
E-mail megerősítve itt: dartmouth.edu
Cím
Hivatkozott rá
Hivatkozott rá
Év
One mouse, one patient paradigm: New avatars of personalized cancer therapy
P Malaney, SV Nicosia, V Davé
Cancer letters 344 (1), 1-12, 2014
3512014
Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseases
VN Uversky, V Davé, LM Iakoucheva, P Malaney, SJ Metallo, RR Pathak, ...
Chemical reviews 114 (13), 6844-6879, 2014
2852014
PTEN proteoforms in biology and disease
P Malaney, VN Uversky, V Davé
Cellular and Molecular Life Sciences 74, 2783-2794, 2017
872017
Intrinsic disorder in PTEN and its interactome confers structural plasticity and functional versatility
P Malaney, RR Pathak, B Xue, VN Uversky, V Davé
Scientific reports 3 (1), 2035, 2013
862013
A unified nomenclature and amino acid numbering for human PTEN
R Pulido, SJ Baker, JT Barata, A Carracedo, VJ Cid, ID Chin-Sang, ...
Science signaling 7 (332), pe15-pe15, 2014
682014
The PTEN Long N-tail is intrinsically disordered: increased viability for PTEN therapy
P Malaney, VN Uversky, V Davé
Molecular Biosystems 9 (11), 2877-2888, 2013
572013
PTEN physically interacts with and regulates E2F1-mediated transcription in lung cancer
P Malaney, E Palumbo, J Semidey-Hurtado, J Hardee, K Stanford, ...
Cell Cycle 17 (8), 947-962, 2018
432018
Uncovering the role of RNA-binding protein hnRNP K in B-cell lymphomas
M Gallardo, P Malaney, MJL Aitken, X Zhang, TM Link, V Shah, ...
JNCI: Journal of the National Cancer Institute 112 (1), 95-106, 2020
252020
Loss of phosphatase and tensin homolog (PTEN) induces leptin-mediated leptin gene expression: feed-forward loop operating in the lung
RR Pathak, A Grover, P Malaney, W Quarni, A Pandit, D Allen-Gipson, ...
Journal of Biological Chemistry 288 (41), 29821-29835, 2013
212013
Identification of intrinsically disordered regions in PTEN and delineation of its function via a network approach
P Malaney, VN Uversky, V Davé
Methods 77, 69-74, 2015
192015
AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill F LT 3-ITD acute myeloid leukemia
SM Post, H Ma, P Malaney, X Zhang, MJL Aitken, PY Mak, VR Ruvolo, ...
Haematologica 107 (6), 1311, 2022
142022
Heterogeneous nuclear ribonucleoprotein K is overexpressed in acute myeloid leukemia and causes myeloproliferation in mice via altered Runx1 splicing
MJL Aitken, P Malaney, X Zhang, SM Herbrich, L Chan, O Benitez, ...
NAR cancer 4 (4), zcac039, 2022
52022
Assessing the role of intrinsic disorder in RNA-binding protein function: hnRNP K as a case study
P Malaney, O Benitez, X Zhang, SM Post
Methods 208, 59-65, 2022
32022
The Eµ-hnRNP K murine model of lymphoma: novel insights into the role of hnRNP K in B-cell malignancies
P Malaney, M Velasco-Estevez, P Aguilar-Garrido, MJL Aitken, LE Chan, ...
Frontiers in immunology 12, 634584, 2021
32021
Combination Therapy with BTK Inhibitor Plus Anti-PD-1 Antibody Results in a Hyperprogressor Phenotype in a Mouse Model of CLL
A Gu, H Ma, X Zhang, P Malaney, M Gallardo, J Liu, SS Neelapu, SM Post
Blood 132, 4416, 2018
32018
Insight into the mechanism of AML del (9q) progression: hnRNP K targets the myeloid master regulators CEBPA (C/EBPα) and SPI1 (PU. 1)
K Rahn, AT Abdallah, L Gan, S Herbrich, R Sonntag, O Benitez, ...
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1867 (1), 195004, 2024
12024
Creating accessibility in academic negotiations
JH Kong, CG Vasquez, S Agrawal, P Malaney, MM Mikedis, AB Moffitt, ...
Trends in Biochemical Sciences 48 (3), 203-210, 2023
12023
Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling
DN Rupani, FI Thege, V Chandra, H Rajaei, RW Cowan, SM Wörmann, ...
Development 150 (2), dev201097, 2023
12023
S104: RBPs dysregulation cause hyper-nucleoli and ribosome gain-of-function driving bone marrow failure
P Aguilar-Garrido, M Velasco, MH Sánchez, MÁN Aguadero, P Malaney, ...
HemaSphere 6, 5-6, 2022
12022
hnRNPK as a Driver of Lymphomagenesis
P Malaney, M Hornbaker, M Gallardo, X Zhang, M McArthur, ...
Clinical Lymphoma, Myeloma and Leukemia 17, S374-S375, 2017
12017
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