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Karina Barbosa
Karina Barbosa
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Title
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Year
The role of TP53 in acute myeloid leukemia: challenges and opportunities
K Barbosa, S Li, PD Adams, AJ Deshpande
Genes, Chromosomes and Cancer 58 (12), 875-888, 2019
1072019
A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing
S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ...
Nature communications 12 (1), 6512, 2021
392021
HIV-1 antisense protein of different clades induces autophagy and associates with the autophagy factor p62
Z Liu, C Torresilla, Y Xiao, PT Nguyen, C Caté, K Barbosa, É Rassart, ...
Journal of virology 93 (2), 10.1128/jvi. 01757-18, 2019
272019
Acute myeloid leukemia driven by the CALM-AF10 fusion gene is dependent on BMI1
K Barbosa, A Deshpande, BR Chen, A Ghosh, Y Sun, S Dutta, M Weetall, ...
Experimental hematology 74, 42-51. e3, 2019
182019
A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML
BR Chen, A Deshpande, K Barbosa, M Kleppe, X Lei, N Yeddula, PS Vela, ...
Blood, The Journal of the American Society of Hematology 137 (24), 3403-3415, 2021
142021
The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations
BJ Klein, A Deshpande, KL Cox, F Xuan, M Zandian, K Barbosa, S Khanal, ...
Nature communications 12 (1), 4130, 2021
102021
The role of DOT1L in normal and malignant hematopoiesis
O Arnold, K Barbosa, AJ Deshpande, N Zhu
Frontiers in Cell and Developmental Biology 10, 917125, 2022
72022
Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells
D Raveendra-Panickar, D Finlay, FI Layng, LJ Lambert, M Celeridad, ...
Journal of Biological Chemistry 298 (1), 2022
62022
Integrated computational and experimental identification of p53, KRAS and VHL mutant selection associated with CRISPR-Cas9 editing
S Sinha, KB Guerra, K Cheng, MDM Leiserson, DM Wilson III, BM Ryan, ...
bioRxiv, 407767, 2018
42018
High-Density Domain-Focused CRISPR Screens Reveal Epigenetic Regulators of Hox/Meis Gene Expression in Acute Myeloid Leukemia
K Barbosa, A Deshpande, P Xiang, BR Chen, A Brown, N Robertson, ...
Blood 136, 2-3, 2020
32020
Transcriptional control of leukemogenesis by the chromatin reader SGF29
K Barbosa, A Deshpande, M Perales, P Xiang, R Murad, AB Pramod, ...
Blood 143 (8), 697-712, 2024
22024
Author Correction: A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing
S Sinha, K Barbosa, K Cheng, MDM Leiserson, P Jain, A Deshpande, ...
Nature Communications 13, 2022
22022
A systematic genome-wide mapping of the oncogenic risks associated with CRISPR-Cas9 editing
S Sinha, K Cheng, MD Leiserson, DM Wilson, BM Ryan, JS Lee, ...
bioRxiv 407767, 2018
22018
Therapeutic targeting of leukemia stem cells in acute myeloid leukemia
K Barbosa, AJ Deshpande
Frontiers in Oncology 13, 2023
2023
High Density Domain-Focused CRISPR Screens Reveal Novel Epigenetic Regulators ofHOX/MEISActivation in Acute Myeloid Leukemia
K Barbosa, A Deshpande, M Perales, P Xiang, R Murad, A Minkina, ...
2022
High Density Domain-Focused CRISPR Screens Reveal Novel Epigenetic Regulators of HOX/MEIS Activation in Acute Myeloid Leukemia
K Barbosa, A Deshpande, M Perales, P Xiang, R Murad, A Minkina, ...
bioRxiv, 2022.12. 12.519332, 2022
2022
Abstract PR004: High-density CRISPR screens reveal mechanisms of chromatin regulation of stemness networks in acute myeloid leukemia
KOB Guerra, A Deshpande, P Xiang, A Minkina, F Schischlik, A Brown, ...
Cancer Research 82 (23_Supplement_2), PR004-PR004, 2022
2022
3030–THE EPIGENETIC REGULATOR LANDSCAPE OF STEMNESS NETWORKS IN ACUTE MYELOID LEUKEMIA
K Barbosa, A Deshpande, P Xiang, A Minkina, F Schischlik, A Brown, ...
Experimental Hematology 111, S59-S60, 2022
2022
A Synthetic Lethal Approach to Eradicate AML Via Synergistic Activation of Pro-Apoptotic p53 By MDM2 and BET Inhibitors
S Li, AL Latif, A Newcombe, K Gilrory, N Robertson, X Lei, D Finlay, ...
Blood 136, 14, 2020
2020
A synthetic lethality approach to eradicate AML via synergistic activation of pro-apoptotic p53 by MDM2 and BET inhibitors
S Li, AL Latif, A Newcombe, K Gilrory, N Robertson, D Finlay, X Lei, ...
EXPERIMENTAL HEMATOLOGY 88, S70-S70, 2020
2020
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