Harmit Singh Malik

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Michael EmermanFred Hutchinson Cancer Research CenterVerified email at fredhutch.org
Steven HenikoffBasic Sciences Division, Fred Hutchinson Cancer Research CenterVerified email at fhcrc.org
Janet YoungStaff Scientist, Fred Hutchinson Cancer Research CenterVerified email at fhcrc.org
Sara SawyerProfessor at the University of Colorado BoulderVerified email at colorado.edu
Kami AhmadFred Hutchinson Cancer Research CenterVerified email at fredhutch.org
Nels C. EldeProfessor of Genetics, University of UtahVerified email at genetics.utah.edu
Nitin PhadnisUniversity of UtahVerified email at utah.edu
Richard N. McLaughlin Jr.Pacific Northwest Research InstituteVerified email at pnri.org
Efrem LimArizona State UniversityVerified email at asu.edu
Lisa KurselUniversity of UtahVerified email at utah.edu
Maulik R PatelVanderbilt UniversityVerified email at vanderbilt.edu
Mia LevineUniversity of PennsylvaniaVerified email at sas.upenn.edu
Jay ShendureProfessor of Genome Sciences, University of WashingtonVerified email at uw.edu
Jacob KitzmanAssociate ProfessorVerified email at umich.edu
Frederick "Erick" A. Matsen IVProfessor, Fred Hutchinson Cancer Research CenterVerified email at fredhutch.org
Connor McCoyFred Hutchinson Cancer Research CenterVerified email at fhcrc.org
Benjamin D. RossDartmouth College Department of Microbiology and ImmunologyVerified email at dartmouth.edu
Eric PhizickyUniversity of RochesterVerified email at urmc.rochester.edu
Meng-Chao YaoAcademia SinicaVerified email at gate.sinica.edu.tw
Joshua AkeyProfessor of Ecology and Evolutionary Biology and Lewis Sigler Institute, Princeton UniversityVerified email at princeton.edu

Harmit Singh Malik

Member, Basic Sciences, Fred Hutchinson Cancer Research Center

Verified email at fhcrc.org - Homepage

Evolutionary genetics


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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020	3555	2020
The centromere paradox: stable inheritance with rapidly evolving DNA S Henikoff, K Ahmad, HS Malik Science 293 (5532), 1098-1102, 2001	1245	2001
Positive selection of primate TRIM5α identifies a critical species-specific retroviral restriction domain SL Sawyer, LI Wu, M Emerman, HS Malik Proceedings of the National Academy of Sciences 102 (8), 2832-2837, 2005	757	2005
Phylogenomics of the nucleosome HS Malik, S Henikoff Nature structural & molecular biology 10 (11), 882-891, 2003	730	2003
The age and evolution of non-LTR retrotransposable elements. HS Malik, WD Burke, TH Eickbush Molecular biology and evolution 16 (6), 793-805, 1999	642	1999
Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G SL Sawyer, M Emerman, HS Malik PLoS biology 2 (9), e275, 2004	535	2004
Rules of engagement: molecular insights from host-virus arms races MD Daugherty, HS Malik Annual review of genetics 46, 677-700, 2012	452	2012
Poised for contagion: evolutionary origins of the infectious abilities of invertebrate retroviruses HS Malik, S Henikoff, TH Eickbush Genome research 10 (9), 1307-1318, 2000	380	2000
Major evolutionary transitions in centromere complexity HS Malik, S Henikoff Cell 138 (6), 1067-1082, 2009	367	2009
A unified phylogeny-based nomenclature for histone variants PB Talbert, K Ahmad, G Almouzni, J Ausió, F Berger, PL Bhalla, ... Epigenetics & chromatin 5 (1), 1-19, 2012	326	2012
Adaptive evolution of Cid, a centromere-specific histone in Drosophila HS Malik, S Henikoff Genetics 157 (3), 1293-1298, 2001	325	2001
Safeguarding gene drive experiments in the laboratory OS Akbari, HJ Bellen, E Bier, SL Bullock, A Burt, GM Church, KR Cook, ... Science 349 (6251), 927-929, 2015	310	2015
Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa PL Oliver, L Goodstadt, JJ Bayes, Z Birtle, KC Roach, N Phadnis, ... PLoS genetics 5 (12), e1000753, 2009	305	2009
Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses NC Elde, SJ Child, MT Eickbush, JO Kitzman, KS Rogers, J Shendure, ... Cell 150 (4), 831-841, 2012	288	2012
The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx ES Lim, OI Fregoso, CO McCoy, FA Matsen, HS Malik, M Emerman Cell host & microbe 11 (2), 194-204, 2012	285	2012
Protein kinase R reveals an evolutionary model for defeating viral mimicry NC Elde, SJ Child, AP Geballe, HS Malik Nature 457 (7228), 485-489, 2009	285	2009
Guidelines for naming nonprimate APOBEC3 genes and proteins RS LaRue, V Andrésdóttir, Y Blanchard, SG Conticello, D Derse, ... Journal of virology 83 (2), 494-497, 2009	275	2009
Origins and evolution of retrotransposons TH Eickbush, HS Malik Mobile DNA ii, 1111-1144, 2002	272*	2002
Phylogenetic analysis of ribonuclease H domains suggests a late, chimeric origin of LTR retrotransposable elements and retroviruses HS Malik, TH Eickbush Genome Research 11 (7), 1187-1197, 2001	269	2001
Modular evolution of the integrase domain in the Ty3/Gypsy class of LTR retrotransposons HS Malik, TH Eickbush Journal of virology 73 (6), 5186-5190, 1999	240	1999

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