Követés
Rajendra Uprety
Rajendra Uprety
Ismeretlen szervezet
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Hivatkozott rá
Év
Structure of the nanobody-stabilized active state of the kappa opioid receptor
T Che, S Majumdar, SA Zaidi, P Ondachi, JD McCorvy, S Wang, ...
Cell 172 (1), 55-67. e15, 2018
3502018
Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair
SM Hancock, R Uprety, A Deiters, JW Chin
Journal of the American Chemical Society 132 (42), 14819-14824, 2010
2572010
Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation
J Luo, R Uprety, Y Naro, C Chou, DP Nguyen, JW Chin, A Deiters
Journal of the American Chemical Society 136 (44), 15551-15558, 2014
1572014
7-Hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects
AC Kruegel, R Uprety, SG Grinnell, C Langreck, EA Pekarskaya, ...
ACS central science 5 (6), 992-1001, 2019
1542019
Genetically encoding an aliphatic diazirine for protein photocrosslinking
C Chou, R Uprety, L Davis, JW Chin, A Deiters
Chemical Science 2 (3), 480-483, 2011
1052011
Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace
MH Baumann, S Majumdar, V Le Rouzic, A Hunkele, R Uprety, XP Huang, ...
Neuropharmacology 134, 101-107, 2018
882018
Regulation of transcription through light-activation and light-deactivation of triplex-forming oligonucleotides in mammalian cells
JM Govan, R Uprety, J Hemphill, MO Lively, A Deiters
ACS chemical biology 7 (7), 1247-1256, 2012
702012
Spatiotemporal control of microRNA function using light-activated antagomirs
CM Connelly, R Uprety, J Hemphill, A Deiters
Molecular BioSystems 8 (11), 2987-2993, 2012
692012
Genetic encoding of caged cysteine and caged homocysteine in bacterial and mammalian cells
R Uprety, J Luo, J Liu, Y Naro, S Samanta, A Deiters
ChemBioChem 15 (12), 1793-1799, 2014
602014
G protein‐biased kratom‐alkaloids and synthetic carfentanil‐amide opioids as potential treatments for alcohol use disorder
AM Gutridge, MT Robins, RJ Cassell, R Uprety, KL Mores, MJ Ko, ...
British journal of pharmacology 177 (7), 1497-1513, 2020
542020
Site-specific promoter caging enables optochemical gene activation in cells and animals
J Hemphill, J Govan, R Uprety, M Tsang, A Deiters
Journal of the American Chemical Society 136 (19), 7152-7158, 2014
512014
Improved synthesis of the two-photon caging group 3-nitro-2-ethyldibenzofuran and its application to a caged thymidine phosphoramidite
H Lusic, R Uprety, A Deiters
Organic letters 12 (5), 916-919, 2010
512010
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site
R Uprety, T Che, SA Zaidi, SG Grinnell, BR Varga, A Faouzi, ST Slocum, ...
Elife 10, e56519, 2021
492021
Conditional control of alternative splicing through light-triggered splice-switching oligonucleotides
J Hemphill, Q Liu, R Uprety, S Samanta, M Tsang, RL Juliano, A Deiters
Journal of the American Chemical Society 137 (10), 3656-3662, 2015
482015
Control of protein function through optochemical translocation
H Engelke, C Chou, R Uprety, P Jess, A Deiters
ACS Synthetic Biology 3 (10), 731-736, 2014
482014
Genetically encoded optical activation of DNA recombination in human cells
J Luo, E Arbely, J Zhang, C Chou, R Uprety, JW Chin, A Deiters
Chemical communications 52 (55), 8529-8532, 2016
452016
Kratom alkaloids, natural and semi-synthetic, show less physical dependence and ameliorate opioid withdrawal
LL Wilson, S Chakraborty, SO Eans, TJ Cirino, HM Stacy, CA Simons, ...
Cellular and molecular neurobiology 41, 1131-1143, 2021
422021
Cellular delivery and photochemical activation of antisense agents through a nucleobase caging strategy
JM Govan, R Uprety, M Thomas, H Lusic, MO Lively, A Deiters
ACS chemical biology 8 (10), 2272-2282, 2013
362013
Oxidative metabolism as a modulator of kratom’s biological actions
S Chakraborty, R Uprety, ST Slocum, T Irie, V Le Rouzic, X Li, LL Wilson, ...
Journal of medicinal chemistry 64 (22), 16553-16572, 2021
302021
Kratom alkaloids as probes for opioid receptor function: Pharmacological characterization of minor indole and oxindole alkaloids from kratom
S Chakraborty, R Uprety, AE Daibani, VL Rouzic, A Hunkele, ...
ACS chemical neuroscience 12 (14), 2661-2678, 2021
242021
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