László Radnai
László Radnai
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DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond
P Rapali, Á Szenes, L Radnai, A Bakos, G Pál, L Nyitray
The FEBS journal 278 (17), 2980-2996, 2011
Alternatively spliced exon B of myosin Va is essential for binding the tail-associated light chain shared by dynein
Z Hódi, AL Németh, L Radnai, C Hetényi, K Schlett, A Bodor, A Perczel, ...
Biochemistry 45 (41), 12582-12595, 2006
Crystal structure of the S100A4–nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism
B Kiss, A Duelli, L Radnai, KA Kékesi, G Katona, L Nyitray
Proceedings of the National Academy of Sciences 109 (16), 6048-6053, 2012
Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome
P Rapali, L Radnai, D Süveges, V Harmat, F Tölgyesi, WY Wahlgren, ...
PloS one 6 (4), e18818, 2011
Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms
L Radnai, P Rapali, Z Hódi, D Süveges, T Molnár, B Kiss, B Bécsi, ...
Journal of Biological Chemistry 285 (49), 38649-38657, 2010
Regulation of the equilibrium between closed and open conformations of annexin A2 by N-terminal phosphorylation and S100A4-binding
P Ecsédi, B Kiss, G Gógl, L Radnai, L Buday, K Koprivanacz, K Liliom, ...
Structure 25 (8), 1195-1207. e5, 2017
Introduction to practical biochemistry
G Hegyi, J Kardos, M Kovács, A Málnási-Csizmadia, L Nyitray, G Pál, ...
Eötvös Loránd University, 2013
DYNLL2 dynein light chain binds to an extended linear motif of myosin 5a tail that has structural plasticity
A Bodor, L Radnai, C Hetényi, P Rapali, A Láng, KE Kövér, A Perczel, ...
Biochemistry 53 (45), 7107-7122, 2014
The scaffold protein Tks4 is required for the differentiation of mesenchymal stromal cells (MSCs) into adipogenic and osteogenic lineages
M Dülk, G Kudlik, A Fekete, D Ernszt, K Kvell, JE Pongrácz, BL Merő, ...
Scientific reports 6 (1), 1-9, 2016
Structural insights into the tyrosine phosphorylation–mediated inhibition of SH3 domain–ligand interactions
B Merő, L Radnai, G Gógl, O Tőke, I Leveles, K Koprivanacz, B Szeder, ...
Journal of Biological Chemistry 294 (12), 4608-4620, 2019
EGF regulates the interaction of Tks4 with Src through its SH2 and SH3 domains
M Dülk, B Szeder, G Glatz, BL Merő, K Koprivanacz, G Kudlik, V Vas, ...
Biochemistry 57 (28), 4186-4196, 2018
The LC8 family of dynein light chains: Multifunctional chaperon-like proteins
Z Hodi, P Rapali, L Radnai, T Molnar, A Szenes, J Kardos, L Buday, ...
Febs Journal 274, 106-106, 2007
The SH3 domain of Caskin1 binds to lysophosphatidic acid suggesting a direct role for the lipid in intracellular signaling
K Koprivanacz, O Tőke, B Besztercei, T Juhász, L Radnai, B Merő, ...
Cellular Signalling 32, 66-75, 2017
A semi-high-throughput adaptation of the NADH-coupled ATPase assay for screening small molecule inhibitors
L Radnai, RF Stremel, JR Sellers, G Rumbaugh, CA Miller
JoVE (Journal of Visualized Experiments), e60017, 2019
Advances in understanding TKS4 and TKS5: Molecular scaffolds regulating cellular processes from podosome and invadopodium formation to differentiation and tissue homeostasis
G Kudlik, T Takács, L Radnai, A Kurilla, B Szeder, K Koprivanacz, ...
International Journal of Molecular Sciences 21 (21), 8117, 2020
Solution NMR Structure of the SH3 Domain of Human Caskin1 Validates the Lack of a Typical Peptide Binding Groove and Supports a Role in Lipid Mediator Binding
O Tőke, K Koprivanacz, L Radnai, B Merő, T Juhász, K Liliom, L Buday
Cells 10 (1), 173, 2021
A simple and robust cell-based assay for the discovery of novel cytokinesis inhibitors
L Radnai, RF Stremel, T Vaissiere, L Lin, M Cameron, WH Martin, ...
Journal of biological methods 7 (3), 2020
Characterization of the Intramolecular Interactions and Regulatory Mechanisms of the Scaffold Protein Tks4
B Merő, K Koprivanacz, A Cserkaszky, L Radnai, V Vas, G Kudlik, G Gógl, ...
International journal of molecular sciences 22 (15), 8103, 2021
Nonmuscle myosin ii inhibitors for substance use relapse
C Miller, PR Griffin, TM Kamenecka, G Rumbaugh, M Surman, S Young, ...
US Patent App. 17/250,203, 2021
Discovery of Selective Inhibitors for In Vitro and In Vivo Interrogation of Skeletal Myosin II
L Radnai, M Surman, M Hafenbreidel, EJ Young, RF Stremel, L Lin, ...
ACS Chemical Biology 16 (11), 2164-2173, 2021
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