Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation L Plate, CB Cooley, JJ Chen, RJ Paxman, CM Gallagher, F Madoux, ... elife 5, e15550, 2016 | 209 | 2016 |
Image analysis platform for identifying artifacts in samples and laboratory consumables P Hodder, LD Scampavia, PE Baillargeon US Patent 8,644,547, 2014 | 200 | 2014 |
Peer Reviewed: From Flow Injection to Bead Injection. J Ruzicka, L Scampavia Analytical Chemistry 71 (7), 257A-263A, 1999 | 191 | 1999 |
Advanced development of primary pancreatic organoid tumor models for high-throughput phenotypic drug screening S Hou, H Tiriac, BP Sridharan, L Scampavia, F Madoux, J Seldin, ... SLAS DISCOVERY: Advancing Life Sciences R&D 23 (6), 574-584, 2018 | 139 | 2018 |
Ebselen, a small-molecule capsid inhibitor of HIV-1 replication S Thenin-Houssier, IMS De Vera, L Pedro-Rosa, A Brady, A Richard, ... Antimicrobial agents and chemotherapy 60 (4), 2195-2208, 2016 | 111 | 2016 |
Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming JMD Grandjean, A Madhavan, L Cech, BO Seguinot, RJ Paxman, E Smith, ... Nature chemical biology 16 (10), 1052-1061, 2020 | 103 | 2020 |
Micro sequential injection: fermentation monitoring of ammonia, glycerol, glucose, and free iron using the novel lab-on-valve system CH Wu, L Scampavia, J Ruzicka, B Zamost Analyst 126 (3), 291-297, 2001 | 75 | 2001 |
A 1536-well 3D viability assay to assess the cytotoxic effect of drugs on spheroids F Madoux, A Tanner, M Vessels, L Willetts, S Hou, L Scampavia, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (5), 516-524, 2017 | 74 | 2017 |
Microsequential injection: anion separations using ‘Lab-on-Valve’coupled with capillary electrophoresis CH Wu, L Scampavia, J Ruzicka Analyst 127 (7), 898-905, 2002 | 69 | 2002 |
Automated affinity capture− release of biotin-containing conjugates using a lab-on-valve apparatus coupled to UV/visible and electrospray ionization mass spectrometry Y Ogata, L Scampavia, J Růžička, CR Scott, MH Gelb, F Tureček Analytical chemistry 74 (18), 4702-4708, 2002 | 66 | 2002 |
Micro sequential injection: automated insulin derivatization and separation using a lab-on-valve capillary electrophoresis system CH Wu, L Scampavia, J Ruzicka Analyst 128 (9), 1123-1130, 2003 | 64 | 2003 |
A coaxial jet mixer for rapid kinetic analysis in flow injection and flow injection cytometry LD Scampavia, G Blankenstein, J Ruzicka, GD Christian Analytical chemistry 67 (17), 2743-2749, 1995 | 64 | 1995 |
LPCAT3 inhibitors remodel the polyunsaturated phospholipid content of human cells and protect from ferroptosis A Reed, TA Ichu, N Milosevich, B Melillo, MA Schafroth, Y Otsuka, ... ACS chemical biology 17 (6), 1607-1618, 2022 | 63 | 2022 |
Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho … T Schröter, D Minond, A Weiser, C Dao, J Habel, T Spicer, P Chase, ... SLAS Discovery 13 (1), 17-28, 2008 | 55 | 2008 |
Real-time monitoring of lactate extrusion and glucose consumption of cultured cells using a lab-on-valve system CM Schulz, L Scampavia, J Ruzicka Analyst 127 (12), 1583-1588, 2002 | 49 | 2002 |
SYNGAP1 controls the maturation of dendrites, synaptic function, and network activity in developing human neurons N Llamosas, V Arora, R Vij, M Kilinc, L Bijoch, C Rojas, A Reich, ... Journal of Neuroscience 40 (41), 7980-7994, 2020 | 47 | 2020 |
Detection of oxygen consumption of cultured adherent cells by bead injection spectroscopy I Lähdesmäki, LD Scampavia, C Beeson, J Ruzicka Analytical chemistry 71 (22), 5248-5252, 1999 | 47 | 1999 |
Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival JW Chang, AM Zuhl, AE Speers, S Niessen, SJ Brown, MM Mulvihill, ... ACS chemical biology 10 (4), 925-932, 2015 | 45 | 2015 |
First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis PB Palde, A Bhaskar, LE Pedró Rosa, F Madoux, P Chase, V Gupta, ... ACS chemical biology 11 (1), 172-184, 2016 | 43 | 2016 |
Bead injection ELISA for the determination of antibodies implicated in type 1 diabetes mellitus AD Carroll, L Scampavia, D Luo, Å Lernmark, J Ruzicka Analyst 128 (9), 1157-1162, 2003 | 42 | 2003 |