Mechanism of blebbistatin inhibition of myosin II M Kovács, J Tóth, C Hetényi, A Málnási-Csizmadia, JR Sellers Journal of Biological Chemistry 279 (34), 35557-35563, 2004 | 1261 | 2004 |
Kinetic Resolution of a Conformational Transition and the ATP Hydrolysis Step Using Relaxation Methods with a Dictyostelium Myosin II Mutant Containing a Single … A Málnási-Csizmadia, DS Pearson, M Kovács, RJ Woolley, MA Geeves, ... Biochemistry 40 (42), 12727-12737, 2001 | 164 | 2001 |
Resolution of Conformational States of Dictyostelium Myosin II Motor Domain Using Tryptophan (W501) Mutants: Implications for the Open-Closed Transition … A Málnási-Csizmadia, RJ Woolley, CR Bagshaw Biochemistry 39 (51), 16135-16146, 2000 | 151 | 2000 |
para‐Nitroblebbistatin, the Non‐Cytotoxic and Photostable Myosin II Inhibitor M Képiró, BH Várkuti, L Végner, G Vörös, G Hegyi, M Varga, ... Angewandte Chemie International Edition 53 (31), 8211-8215, 2014 | 135 | 2014 |
Myosin cleft movement and its coupling to actomyosin dissociation PB Conibear, CR Bagshaw, PG Fajer, M Kovács, A Málnási-Csizmadia Nature Structural & Molecular Biology 10 (10), 831-835, 2003 | 122 | 2003 |
A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative BH Várkuti, M Képiró, IÁ Horváth, L Végner, S Ráti, Á Zsigmond, G Hegyi, ... Scientific reports 6 (1), 26141, 2016 | 121 | 2016 |
Targeting myosin by blebbistatin derivatives: optimization and pharmacological potential AÁ Rauscher, M Gyimesi, M Kovács, A Málnási-Csizmadia Trends in biochemical sciences 43 (9), 700-713, 2018 | 107 | 2018 |
Phase separation by ssDNA binding protein controlled via protein− protein and protein− DNA interactions GM Harami, ZJ Kovács, R Pancsa, J Pálinkás, V Baráth, K Tárnok, ... Proceedings of the National Academy of Sciences 117 (42), 26206-26217, 2020 | 106 | 2020 |
Differential actin binding along the PEVK domain of skeletal muscle titin A Nagy, P Cacciafesta, L Grama, A Kengyel, A Málnási-Csizmadia, ... Journal of cell science 117 (24), 5781-5789, 2004 | 96 | 2004 |
Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme J Tóth, B Varga, M Kovács, A Málnási-Csizmadia, BG Vértessy Journal of Biological Chemistry 282 (46), 33572-33582, 2007 | 95 | 2007 |
Drug effect prediction by polypharmacology-based interaction profiling Z Simon, Á Peragovics, M Vigh-Smeller, G Csukly, L Tombor, Z Yang, ... Journal of chemical information and modeling 52 (1), 134-145, 2012 | 79 | 2012 |
A novel actin binding site of myosin required for effective muscle contraction BH Várkuti, Z Yang, B Kintses, P Erdélyi, I Bárdos-Nagy, AL Kovács, ... Nature structural & molecular biology 19 (3), 299-306, 2012 | 76 | 2012 |
Emerging complex pathways of the actomyosin powerstroke A Málnási-Csizmadia, M Kovács Trends in biochemical sciences 35 (12), 684-690, 2010 | 76 | 2010 |
Reversible movement of switch 1 loop of myosin determines actin interaction B Kintses, M Gyimesi, DS Pearson, MA Geeves, W Zeng, CR Bagshaw, ... The EMBO journal 26 (1), 265-274, 2007 | 73 | 2007 |
Dynamics of actomyosin interactions in relation to the cross-bridge cycle. W Zeng, PB Conibear, JL Dickens, RA Cowie, S Wakelin, ... Philosophical Transactions of the Royal Society B: Biological Sciences 359 …, 2004 | 72 | 2004 |
The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II M Gyimesi, B Kintses, A Bodor, A Perczel, S Fischer, CR Bagshaw, ... Journal of Biological Chemistry 283 (13), 8153-8163, 2008 | 67 | 2008 |
The Dynamics of the Relay Loop Tryptophan Residue in theDictyostelium Myosin Motor Domain and the Origin of Spectroscopic Signals A Málnási-Csizmadia, M Kovács, RJ Woolley, SW Botchway, ... Journal of Biological Chemistry 276 (22), 19483-19490, 2001 | 64 | 2001 |
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke B Takács, N Billington, M Gyimesi, B Kintses, A Málnási-Csizmadia, ... Proceedings of the National Academy of Sciences 107 (15), 6799-6804, 2010 | 62 | 2010 |
Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges L Gombos, J Kardos, A Patthy, P Medveczky, L Szilágyi, ... Biochemistry 47 (6), 1675-1684, 2008 | 52 | 2008 |
Analysis of Nucleotide Binding to DictyosteliumMyosin II Motor Domains Containing a Single Tryptophan Near the Active Site M Kovacs, A Málnási-Csizmadia, RJ Woolley, CR Bagshaw Journal of Biological Chemistry 277 (32), 28459-28467, 2002 | 52 | 2002 |