Andras Malnasi-Csizmadia
Andras Malnasi-Csizmadia
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Mechanism of blebbistatin inhibition of myosin II
M Kovács, J Tóth, C Hetényi, A Málnási-Csizmadia, JR Sellers
Journal of Biological Chemistry 279 (34), 35557-35563, 2004
Kinetic Resolution of a Conformational Transition and the ATP Hydrolysis Step Using Relaxation Methods with a Dictyostelium Myosin II Mutant Containing a Single …
A Málnási-Csizmadia, DS Pearson, M Kovács, RJ Woolley, MA Geeves, ...
Biochemistry 40 (42), 12727-12737, 2001
Resolution of Conformational States of Dictyostelium Myosin II Motor Domain Using Tryptophan (W501) Mutants:  Implications for the Open-Closed Transition …
A Málnási-Csizmadia, RJ Woolley, CR Bagshaw
Biochemistry 39 (51), 16135-16146, 2000
para‐Nitroblebbistatin, the Non‐Cytotoxic and Photostable Myosin II Inhibitor
M Képiró, BH Várkuti, L Végner, G Vörös, G Hegyi, M Varga, ...
Angewandte Chemie International Edition 53 (31), 8211-8215, 2014
Myosin cleft movement and its coupling to actomyosin dissociation
PB Conibear, CR Bagshaw, PG Fajer, M Kovács, A Málnási-Csizmadia
Nature Structural & Molecular Biology 10 (10), 831-835, 2003
A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative
BH Várkuti, M Képiró, IÁ Horváth, L Végner, S Ráti, Á Zsigmond, G Hegyi, ...
Scientific reports 6 (1), 26141, 2016
Targeting myosin by blebbistatin derivatives: optimization and pharmacological potential
AÁ Rauscher, M Gyimesi, M Kovács, A Málnási-Csizmadia
Trends in biochemical sciences 43 (9), 700-713, 2018
Differential actin binding along the PEVK domain of skeletal muscle titin
A Nagy, P Cacciafesta, L Grama, A Kengyel, A Málnási-Csizmadia, ...
Journal of cell science 117 (24), 5781-5789, 2004
Phase separation by ssDNA binding protein controlled via protein− protein and protein− DNA interactions
GM Harami, ZJ Kovács, R Pancsa, J Pálinkás, V Baráth, K Tárnok, ...
Proceedings of the National Academy of Sciences 117 (42), 26206-26217, 2020
Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme
J Tóth, B Varga, M Kovács, A Málnási-Csizmadia, BG Vértessy
Journal of biological chemistry 282 (46), 33572-33582, 2007
Drug effect prediction by polypharmacology-based interaction profiling
Z Simon, Á Peragovics, M Vigh-Smeller, G Csukly, L Tombor, Z Yang, ...
Journal of chemical information and modeling 52 (1), 134-145, 2012
A novel actin binding site of myosin required for effective muscle contraction
BH Várkuti, Z Yang, B Kintses, P Erdélyi, I Bárdos-Nagy, AL Kovács, ...
Nature structural & molecular biology 19 (3), 299-306, 2012
Emerging complex pathways of the actomyosin powerstroke
A Málnási-Csizmadia, M Kovács
Trends in biochemical sciences 35 (12), 684-690, 2010
Reversible movement of switch 1 loop of myosin determines actin interaction
B Kintses, M Gyimesi, DS Pearson, MA Geeves, W Zeng, CR Bagshaw, ...
The EMBO journal 26 (1), 265-274, 2007
Dynamics of actomyosin interactions in relation to the cross-bridge cycle.
W Zeng, PB Conibear, JL Dickens, RA Cowie, S Wakelin, ...
Philosophical Transactions of the Royal Society B: Biological Sciences 359 …, 2004
The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II
M Gyimesi, B Kintses, A Bodor, A Perczel, S Fischer, CR Bagshaw, ...
Journal of biological chemistry 283 (13), 8153-8163, 2008
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke
B Takács, N Billington, M Gyimesi, B Kintses, A Málnási-Csizmadia, ...
Proceedings of the National Academy of Sciences 107 (15), 6799-6804, 2010
The Dynamics of the Relay Loop Tryptophan Residue in theDictyostelium Myosin Motor Domain and the Origin of Spectroscopic Signals
A Málnási-Csizmadia, M Kovács, RJ Woolley, SW Botchway, ...
Journal of Biological Chemistry 276 (22), 19483-19490, 2001
Analysis of Nucleotide Binding to DictyosteliumMyosin II Motor Domains Containing a Single Tryptophan Near the Active Site
M Kovacs, A Málnási-Csizmadia, RJ Woolley, CR Bagshaw
Journal of Biological Chemistry 277 (32), 28459-28467, 2002
Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges
L Gombos, J Kardos, A Patthy, P Medveczky, L Szilágyi, ...
Biochemistry 47 (6), 1675-1684, 2008
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