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Kiruphagaran Thangaraju
Kiruphagaran Thangaraju
Center for Blood Oxygen Transport and Hemostasis, University of Maryland, Baltimore
Verified email at som.umaryland.edu
Title
Cited by
Cited by
Year
Extracellular vesicles from red blood cells and their evolving roles in health, coagulopathy and therapy
K Thangaraju, SN Neerukonda, U Katneni, PW Buehler
International journal of molecular sciences 22 (1), 153, 2020
972020
Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19
Cells 10 (9), 2293, 2021
422021
Isopeptidase activity of human transglutaminase 2: disconnection from transamidation and characterization by kinetic parameters
R Király, K Thangaraju, Z Nagy, R Collighan, Z Nemes, M Griffin, L Fésüs
Amino acids 48 (1), 31-40, 2016
312016
The alternative initiation factor eIF2A plays key role in RAN translation of myotonic dystrophy type 2 CCUG• CAGG repeats
SK Tusi, L Nguyen, K Thangaraju, J Li, JD Cleary, T Zu, LPW Ranum
Human Molecular Genetics 30 (11), 1020-1029, 2021
162021
Coagulation potential and the integrated omics of extracellular vesicles from COVID-19 positive patient plasma
S Setua, K Thangaraju, M Dzieciatkowska, RB Wilkerson, T Nemkov, ...
Scientific reports 12 (1), 22191, 2022
112022
The impact of age and BMI on the VWF/ADAMTS13 axis and simultaneous thrombin and plasmin generation in hospitalized COVID-19 patients
K Thangaraju, U Katneni, IJ Akpan, K Tanaka, T Thomas, S Setua, ...
Frontiers in medicine 8, 817305, 2022
82022
Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2
K Thangaraju, R Király, MA Demeny, J András Mótyán, M Fuxreiter, ...
PloS one 12 (3), e0172189, 2017
82017
Computational analyses of the effect of novel amino acid clusters of human transglutaminase 2 on its structure and function
K Thangaraju, R Király, JA Mótyán, VA Ambrus, M Fuxreiter, L Fésüs
Amino acids 49, 605-614, 2017
72017
Real-time kinetic method to monitor isopeptidase activity of transglutaminase 2 on protein substrate
K Thangaraju, B Biri, G Schlosser, B Kiss, L Nyitray, L Fésüs, R Király
Analytical Biochemistry 505, 36-42, 2016
62016
A pharmacokinetic and plasmin-generation pharmacodynamic assessment of a tranexamic acid regimen designed for cardiac surgery with cardiopulmonary bypass
ER Strauss, S Li, R Henderson, R Carpenter, D Guo, K Thangaraju, ...
Journal of Cardiothoracic and Vascular Anesthesia 36 (8), 2473-2482, 2022
42022
In vitro effects of emicizumab on activated clotting time in blood samples from cardiac surgical patients
KA Tanaka, R Henderson, K Thangaraju, Y Morita, MA Mazzeffi, E Strauss, ...
Haemophilia 28 (1), 183-190, 2022
32022
Mechanical stimuli such as shear stress and piezo1 stimulation generate red blood cell extracellular vesicles
GS Sangha, CM Weber, RM Sapp, S Setua, K Thangaraju, M Pettebone, ...
Frontiers in Physiology 14, 1246910, 2023
12023
Biophysical Analysis and Preclinical Pharmacokinetics–Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute
A Greenfield, DR Lamb, X Gu, K Thangaraju, S Setua, A Yahya, A Vahedi, ...
Biomacromolecules 24 (4), 1855-1870, 2023
12023
The Molecular Size of Bioengineered Oxygen Carriers Determines Tissue Oxygenation in a Hypercholesterolemia Guinea Pig Model of Hemorrhagic Shock and Resuscitation
DR Lamb, A Greenfield, K Thangaraju, S Setua, G Eiker, Q Wang, ...
Molecular Pharmaceutics 20 (11), 5739-5752, 2023
2023
Metabolic and Proteomic Divergence Is Present in Circulating Monocytes and Tissue-Resident Macrophages from Berkeley Sickle Cell Anemia and β-Thalassemia Mice
C Lisk, F Cendali, S Setua, K Thangaraju, DI Pak, D Swindle, ...
Journal of Proteome Research 22 (9), 2925-2935, 2023
2023
Extracellular Vesicle Size Reveals Cargo Specific to Coagulation and Inflammation in Pediatric and Adult Sickle Cell Disease
K Thangaraju, S Setua, C Lisk, D Swindle, D Stephenson, ...
Clinical and Applied Thrombosis/Hemostasis 29, 10760296231186144, 2023
2023
Biological and Clinical Factors contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19 (preprint)
A D'Alessandro, I Akpan, T Thomas, J Reisz, F Cendali, F Gamboni, ...
2021
Identification of repeat expansion mutations using novel deactivated-Cas9-based tools
L Nguyen, K Thangaraju, R Ajredini, PT Ranum, BL Davidson, ET Wang, ...
AAIC Neuroscience Next, 2020
2020
Significance of evolutionary changes in human transglutaminases
K Thangaraju, M Fuxreiter, L Fésüs
AMINO ACIDS 47 (8), 1629-1629, 2015
2015
Amino acid variants in human transglutaminase 2 and their biological relevance
K Thangaraju
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Articles 1–20