Metformin: from mechanisms of action to therapies M Foretz, B Guigas, L Bertrand, M Pollak, B Viollet Cell metabolism 20 (6), 953-966, 2014 | 1373 | 2014 |
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia AS Marsin, L Bertrand, MH Rider, J Deprez, C Beauloye, MF Vincent, ... Current Biology 10 (20), 1247-1255, 2000 | 1018 | 2000 |
Activation of AMP‐activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders B Viollet, M Foretz, B Guigas, S Horman, R Dentin, L Bertrand, L Hue, ... The Journal of physiology 574 (1), 41-53, 2006 | 650 | 2006 |
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis S Horman, GJ Browne, U Krause, JV Patel, D Vertommen, L Bertrand, ... Current biology 12 (16), 1419-1423, 2002 | 558 | 2002 |
6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis MH Rider, L Bertrand, D Vertommen, PA Michels, GG Rousseau, L Hue Biochemical Journal 381 (Pt 3), 561, 2004 | 490 | 2004 |
The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase AS Marsin, C Bouzin, L Bertrand, L Hue Journal of Biological Chemistry 277 (34), 30778-30783, 2002 | 456 | 2002 |
Insulin signalling in the heart L Bertrand, S Horman, C Beauloye, JL Vanoverschelde Cardiovascular research 79 (2), 238-248, 2008 | 361 | 2008 |
AMPK: Lessons from transgenic and knockout animals B Viollet, Y Athea, R Mounier, B Guigas, E Zarrinpashneh, S Horman, ... Frontiers in Bioscience (Landmark Edition) 14, 19, 2009 | 356 | 2009 |
Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKα2 but not AMPKα1 K Sakamoto, E Zarrinpashneh, GR Budas, AC Pouleur, A Dutta, ... American Journal of Physiology-Endocrinology And Metabolism 290 (5), E780-E788, 2006 | 253 | 2006 |
5-Aminoimidazole-4-Carboxamide-1-β-d-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase–Independent Effect on Glucokinase … B Guigas, L Bertrand, N Taleux, M Foretz, N Wiernsperger, D Vertommen, ... Diabetes 55 (4), 865-874, 2006 | 217 | 2006 |
Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia A Mora, AM Davies, L Bertrand, I Sharif, GR Budas, S Jovanović, ... The EMBO journal 22 (18), 4666-4676, 2003 | 217 | 2003 |
AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure C Beauloye, L Bertrand, S Horman, L Hue Cardiovascular research 90 (2), 224-233, 2011 | 213 | 2011 |
Control of p70 ribosomal protein S6 kinase and acetyl‐CoA carboxylase by AMP‐activated protein kinase and protein phosphatases in isolated hepatocytes U Krause, L Bertrand, L Hue European journal of biochemistry 269 (15), 3751-3759, 2002 | 203 | 2002 |
AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation R Gélinas, F Mailleux, J Dontaine, L Bultot, B Demeulder, A Ginion, ... Nature communications 9 (1), 374, 2018 | 194 | 2018 |
AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B L Bertrand, A Ginion, C Beauloye, AD Hebert, B Guigas, L Hue, ... American Journal of Physiology-Heart and Circulatory Physiology 291 (1 …, 2006 | 177 | 2006 |
Enhanced Expression of β3-Adrenoceptors in Cardiac Myocytes Attenuates Neurohormone-Induced Hypertrophic Remodeling Through Nitric Oxide Synthase C Belge, J Hammond, E Dubois-Deruy, B Manoury, J Hamelet, ... Circulation 129 (4), 451-462, 2014 | 168 | 2014 |
Insulin antagonizes AMP-activated protein kinase activation by ischemia or anoxia in rat hearts, without affecting total adenine nucleotides C Beauloye, AS Marsin, L Bertrand, U Krause, DG Hardie, ... FEBS letters 505 (3), 348-352, 2001 | 161 | 2001 |
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia PP Prévot, A Simion, A Grimont, M Colletti, A Khalaileh, G Van den Steen, ... Gut, 2012 | 147 | 2012 |
Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways L Hue, C Beauloye, AS Marsin, L Bertrand, S Horman, MH Rider Journal of molecular and cellular cardiology 34 (9), 1091-1097, 2002 | 135 | 2002 |
Creatine enhances differentiation of myogenic C2C12 cells by activating both p38 and Akt/PKB pathways L Deldicque, D Theisen, L Bertrand, P Hespel, L Hue, M Francaux American Journal of Physiology-Cell Physiology 293 (4), C1263-C1271, 2007 | 134 | 2007 |