Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ... Autophagy 8 (4), 445-544, 2012 | 13105* | 2012 |
Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases BG Vértessy, J Tóth Accounts of chemical research 42 (1), 97-106, 2009 | 294 | 2009 |
Structural biology and regulation of protein import into the nucleus M Christie, CW Chang, G Róna, KM Smith, AG Stewart, AAS Takeda, ... Journal of molecular biology 428 (10), 2060-2090, 2016 | 252 | 2016 |
Elasticity of the human red cell membrane skeleton. Effects of temperature and denaturants BG Vertessy, TL Steck Biophysical journal 55 (2), 255-262, 1989 | 120 | 1989 |
Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase*♦ O Barabás, V Pongrácz, J Kovári, M Wilmanns, BG Vértessy Journal of Biological Chemistry 279 (41), 42907-42915, 2004 | 116 | 2004 |
Malaria pigment crystals as magnetic micro-rotors: key for high-sensitivity diagnosis A Butykai, A Orbán, V Kocsis, D Szaller, S Bordács, E Tátrai-Szekeres, ... Scientific reports 3 (1), 1431, 2013 | 105 | 2013 |
Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells J Nikkilä, R Kumar, J Campbell, I Brandsma, HN Pemberton, F Wallberg, ... British journal of cancer 117 (1), 113-123, 2017 | 104 | 2017 |
Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme J Tóth, B Varga, M Kovács, A Málnási-Csizmadia, BG Vértessy Journal of biological chemistry 282 (46), 33572-33582, 2007 | 93 | 2007 |
Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase B Varga, O Barabás, J Kovári, J Tóth, É Hunyadi-Gulyás, É Klement, ... FEBS letters 581 (24), 4783-4788, 2007 | 89 | 2007 |
Quantitative determination of uracil residues in Escherichia coli DNA: Contribution of ung, dug, and dut genes to uracil avoidance SU Lari, CY Chen, BG Vertéssy, J Morré, SE Bennett DNA repair 5 (12), 1407-1420, 2006 | 89 | 2006 |
Alternative binding of two sequential glycolytic enzymes to microtubules: molecular studies in the phosphofructokinase/aldolase/microtubule system BG Vértessy, F Orosz, J Kovács, J Ovádi Journal of Biological Chemistry 272 (41), 25542-25546, 1997 | 87 | 1997 |
p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells M Periyasamy, AK Singh, C Gemma, C Kranjec, R Farzan, DA Leach, ... Nucleic acids research 45 (19), 11056-11069, 2017 | 86 | 2017 |
Uracil-Containing DNA in Drosophila: Stability, Stage-Specific Accumulation, and Developmental Involvement V Muha, A Horváth, A Békési, M Pukáncsik, B Hodoscsek, G Merényi, ... PLoS genetics 8 (6), e1002738, 2012 | 86 | 2012 |
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor B Varga, O Barabás, E Takács, N Nagy, P Nagy, BG Vértessy Biochemical and biophysical research communications 373 (1), 8-13, 2008 | 83 | 2008 |
Simultaneous Binding of Drugs with Different Chemical Structures to Ca2+-Calmodulin: Crystallographic and Spectroscopic Studies, BG Vertessy, V Harmat, Z Böcskei, G Náray-Szabó, F Orosz, J Ovádi Biochemistry 37 (44), 15300-15310, 1998 | 82 | 1998 |
Flexible glycine rich motif of Escherichia coli deoxyuridine triphosphate nucleotidohydrolase is important for functional but not for structural integrity of the enzyme BG Vertessy Proteins: Structure, Function, and Bioinformatics 28 (4), 568-579, 1997 | 76 | 1997 |
Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase I Pecsi, I Leveles, V Harmat, BG Vertessy, J Toth Nucleic acids research 38 (20), 7179-7186, 2010 | 75 | 2010 |
The dUTPase enzyme is essential in Mycobacterium smegmatis I Pecsi, R Hirmondo, AC Brown, A Lopata, T Parish, BG Vertessy, J Tóth PloS one 7 (5), e37461, 2012 | 69 | 2012 |
Altered subunit communication in subfamilies of trimeric dUTPases A Fiser, BG Vértessy Biochemical and biophysical research communications 279 (2), 534-542, 2000 | 68 | 2000 |
Catalytic and structural role of the metal ion in dUTP pyrophosphatase D Mustafi, A Bekesi, BG Vertessy, MW Makinen Proceedings of the National Academy of Sciences 100 (10), 5670-5675, 2003 | 67 | 2003 |
Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins V Nemeth-Pongracz, O Barabas, M Fuxreiter, I Simon, I Pichova, ... Nucleic acids research 35 (2), 495-505, 2007 | 65 | 2007 |
Developmental regulation of dUTPase in Drosophila melanogaster A Békési, I Zagyva, E Hunyadi-Gulyás, V Pongrácz, J Kovári, AO Nagy, ... Journal of Biological Chemistry 279 (21), 22362-22370, 2004 | 64 | 2004 |
The complete triphosphate moiety of non-hydrolyzable substrate analogues is required for a conformational shift of the flexible C-terminus in E. coli dUTP pyrophosphatase BG Vertessy, G Larsson, T Persson, AC Bergman, R Persson, PO Nyman FEBS letters 421 (1), 83-88, 1998 | 63 | 1998 |
Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric … J Kovári, O Barabás, E Takács, A Békési, Z Dubrovay, V Pongrácz, ... Journal of Biological Chemistry 279 (17), 17932-17944, 2004 | 62 | 2004 |
Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control JE Szabo, V Németh, V Papp-Kádár, K Nyíri, I Leveles, AA Bendes, ... Nucleic acids research 42 (19), 11912-11920, 2014 | 59 | 2014 |
Immobilization of Phenylalanine Ammonia‐Lyase on Single‐Walled Carbon Nanotubes for Stereoselective Biotransformations in Batch and Continuous‐Flow Modes JH Bartha‐Vári, MI Toşa, FD Irimie, D Weiser, Z Boros, BG Vértessy, ... ChemCatChem 7 (7), 1122-1128, 2015 | 58 | 2015 |
Transient-time analysis of substrate-channelling in interacting enzyme systems J Ovádi, P Tompa, B Vértessy, F Orosz, T Keleti, GR Welch Biochemical Journal 257 (1), 187-190, 1989 | 58 | 1989 |
Phenylalanine Ammonia‐Lyase‐Catalyzed Deamination of an Acyclic Amino Acid: Enzyme Mechanistic Studies Aided by a Novel Microreactor Filled with Magnetic Nanoparticles D Weiser, LC Bencze, G Bánóczi, F Ender, R Kiss, E Kókai, A Szilágyi, ... ChemBioChem 16 (16), 2283-2288, 2015 | 56 | 2015 |
A new potent calmodulin antagonist with arylalkylamine structure: crystallographic, spectroscopic and functional studies V Harmat, Z Böcskei, G Náray-Szabó, I Bata, AS Csutor, I Hermecz, ... Journal of molecular biology 297 (3), 747-755, 2000 | 56 | 2000 |
A simple approach to detect active‐site‐directed enzyme‐enzyme interactions: The aldolase/glycerol‐phosphate‐dehydrogenase enzyme system B Vértessy, J Ovádi European Journal of Biochemistry 164 (3), 655-659, 1987 | 55 | 1987 |
Preventive DNA repair by sanitizing the cellular (deoxy) nucleoside triphosphate pool GN Nagy, I Leveles, BG Vértessy The FEBS journal 281 (18), 4207-4223, 2014 | 50 | 2014 |
Silicon carbide quantum dots for bioimaging D Beke, Z Szekrényes, D Pálfi, G Róna, I Balogh, PA Maák, G Katona, ... Journal of Materials Research 28 (2), 205-209, 2013 | 50 | 2013 |
Regulation of the equilibrium between closed and open conformations of annexin A2 by N-terminal phosphorylation and S100A4-binding P Ecsédi, B Kiss, G Gógl, L Radnai, L Buday, K Koprivanacz, K Liliom, ... Structure 25 (8), 1195-1207. e5, 2017 | 49 | 2017 |
From “fluctuation fit” to “conformational selection”: evolution, rediscovery, and integration of a concept BG Vértessy, F Orosz Bioessays 33 (1), 30-34, 2011 | 49 | 2011 |
A one-step method for quantitative determination of uracil in DNA by real-time PCR A Horvath, BG Vertessy Nucleic acids research 38 (21), e196-e196, 2010 | 49 | 2010 |
Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination I Pécsi, JE Szabó, SD Adams, I Simon, JR Sellers, BG Vértessy, J Tóth Proceedings of the National Academy of Sciences 108 (35), 14437-14442, 2011 | 48 | 2011 |
Specific derivatization of the active site tyrosine in dUTPase perturbs ligand binding to the active site BG Vertessy, R Persson, AM Rosengren, M Zeppezauer, PO Nyman Biochemical and biophysical research communications 219 (2), 294-300, 1996 | 48 | 1996 |
Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans P Erdélyi, É Borsos, K Takács-Vellai, T Kovács, AL Kovács, T Sigmond, ... Journal of cell science 124 (9), 1510-1518, 2011 | 47 | 2011 |
Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights G Rona, M Marfori, M Borsos, I Scheer, E Takács, J Toth, F Babos, ... Acta Crystallographica Section D: Biological Crystallography 69 (12), 2495-2505, 2013 | 46 | 2013 |
The control of cell metabolism for homogeneous vs. heterogeneous enzyme systems GR Welch, T Keleti, B Vértessy Journal of theoretical biology 130 (4), 407-422, 1988 | 46 | 1988 |
Structural characterization of arginine fingers: identification of an arginine finger for the pyrophosphatase dUTPases GN Nagy, R Suardíaz, A Lopata, O Ozohanics, K Vékey, BR Brooks, ... Journal of the American Chemical Society 138 (45), 15035-15045, 2016 | 44 | 2016 |
Methylene substitution at the α–β bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site J Kovári, O Barabás, B Varga, A Békési, F Tölgyesi, J Fidy, J Nagy, ... Proteins: Structure, Function, and Bioinformatics 71 (1), 308-319, 2008 | 44 | 2008 |
Improving thermostability and catalytic activity of pyranose 2‐oxidase from Trametes multicolor by rational and semi‐rational design O Spadiut, C Leitner, C Salaheddin, B Varga, BG Vertessy, TC Tan, ... The FEBS Journal 276 (3), 776-792, 2009 | 43 | 2009 |
A tradeoff between protein stability and conformational mobility in homotrimeric dUTPases E Takács, VK Grolmusz, BG Vértessy FEBS letters 566 (1-3), 48-54, 2004 | 42 | 2004 |
Covalently immobilized Trp60Cys mutant of ω-transaminase from Chromobacterium violaceum for kinetic resolution of racemic amines in batch and continuous-flow modes E Abaházi, P Sátorhelyi, B Erdélyi, BG Vértessy, H Land, C Paizs, ... Biochemical engineering journal 132, 270-278, 2018 | 41 | 2018 |
A viral suppressor of RNA silencing inhibits ARGONAUTE 1 function by precluding target RNA binding to pre-assembled RISC E Kenesi, A Carbonell, R Lozsa, B Vértessy, L Lakatos Nucleic acids research 45 (13), 7736-7750, 2017 | 41 | 2017 |
Enhanced Cellular Uptake of a New, in Silico Identified Antitubercular Candidate by Peptide Conjugation K Horváti, B Bacsa, N Szabó, S Dávid, G Mező, V Grolmusz, B Vértessy, ... Bioconjugate chemistry 23 (5), 900-907, 2012 | 41 | 2012 |
Proteins with Complex Architecture as Potential Targets for Drug Design: A Case Study of Mycobacterium tuberculosis B Mészáros, J Tóth, BG Vértessy, Z Dosztányi, I Simon PLoS computational biology 7 (7), e1002118, 2011 | 40 | 2011 |
Molecular shape and prominent role of β-strand swapping in organization of dUTPase oligomers E Takács, O Barabás, MV Petoukhov, DI Svergun, BG Vértessy FEBS letters 583 (5), 865-871, 2009 | 40 | 2009 |
Immobilized whole-cell transaminase biocatalysts for continuous-flow kinetic resolution of amines Z Molnár, E Farkas, Á Lakó, B Erdélyi, W Kroutil, BG Vértessy, C Paizs, ... Catalysts 9 (5), 438, 2019 | 39 | 2019 |
Detection of uracil within DNA using a sensitive labeling method for in vitro and cellular applications G Rona, I Scheer, K Nagy, HL Pálinkás, G Tihanyi, M Borsos, A Békési, ... Nucleic acids research 44 (3), e28-e28, 2016 | 39 | 2016 |
Pyruvate Kinase as a Microtubule Destabilizing Factorin Vitro BG Vértessy, D Bánkfalvi, J Kovács, P Löw, A Lehotzky, J Ovádi Biochemical and biophysical research communications 254 (2), 430-435, 1999 | 39 | 1999 |
Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism G Merényi, J Kovári, J Tóth, E Takács, I Zagyva, A Erdei, BG Vértessy Nucleosides, Nucleotides and Nucleic Acids 30 (6), 369-390, 2011 | 38 | 2011 |
Identification of tyrosine as a functional residue in the active site of Escherichia coli dUTPase BG Vertessy, P Zalud, PO Nyman, M Zeppezauer Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1994 | 38 | 1994 |
Life without dUTPase C Kerepesi, JE Szabó, V Papp-Kádár, O Dobay, D Szabó, V Grolmusz, ... Frontiers in Microbiology 7, 1768, 2016 | 37 | 2016 |
Mutations decouple proton transfer from phosphate cleavage in the dutpase catalytic reaction A Lopata, PG Jambrina, PK Sharma, BR Brooks, J Toth, BG Vertessy, ... Acs Catalysis 5 (6), 3225-3237, 2015 | 37 | 2015 |
Antimycobacterial activity of peptide conjugate of pyridopyrimidine derivative against Mycobacterium tuberculosis in a series of in vitro and in vivo models B Bacsa, N Szabó, K Fodor, G Balka, M Rusvai, É Kiss, G Mező, ... Tuberculosis 95, S207-S211, 2015 | 37 | 2015 |
Triosephosphate isomerase deficiency: predictions and facts F Orosz, BG Vértessy, S Hollán, M Horányi, J Ovádi Journal of theoretical biology 182 (3), 437-447, 1996 | 37 | 1996 |
Neutron scattering studies on dUTPase complex in the presence of bioprotectant systems B Varga, F Migliardo, E Takacs, B Vertessy, S Magazu, C Mondelli Chemical Physics 345 (2-3), 250-258, 2008 | 35 | 2008 |
Characterization of microtubule− phosphofructokinase complex: specific effects of MgATP and vinblastine BG Vértessy, J Kovács, P Löw, A Lehotzky, A Molnár, F Orosz, J Ovádi Biochemistry 36 (8), 2051-2062, 1997 | 35 | 1997 |
Cross-species inhibition of dUTPase via the Staphylococcal Stl protein perturbs dNTP pool and colony formation in Mycobacterium R Hirmondó, JE Szabó, K Nyíri, S Tarjányi, P Dobrotka, J Tóth, ... DNA repair 30, 21-27, 2015 | 34 | 2015 |
Expression and properties of the highly alkalophilic phenylalanine ammonia-lyase of thermophilic Rubrobacter xylanophilus K Kovacs, G Banoczi, A Varga, I Szabo, A Holczinger, G Hornyanszky, ... PLoS One 9 (1), e85943, 2014 | 34 | 2014 |
Structure and enzymatic mechanism of a moonlighting dUTPase I Leveles, V Németh, JE Szabó, V Harmat, K Nyíri, ÁÁ Bendes, ... Acta Crystallographica Section D: Biological Crystallography 69 (12), 2298-2308, 2013 | 34 | 2013 |
Preparation of unnatural amino acids with ammonia-lyases and 2, 3-aminomutases L Poppe, C Paizs, K Kovács, FD Irimie, B Vértessy Unnatural Amino Acids: Methods and Protocols, 3-19, 2012 | 34 | 2012 |
Interaction of a new bis‐indol derivative, KAR‐2 with tubulin and its antimitotic activity F Orosz, J Kovács, P Löw, BG Vértessy, Z Urbányi, T Ács, T Keve, J Ovádi British journal of pharmacology 121 (5), 947-954, 1997 | 34 | 1997 |
A novel fruitfly protein under developmental control degrades uracil-DNA A Békési, M Pukáncsik, V Muha, I Zagyva, I Leveles, E Hunyadi-Gulyás, ... Biochemical and biophysical research communications 355 (3), 643-648, 2007 | 32 | 2007 |
Differential control of dNTP biosynthesis and genome integrity maintenance by the dUTPase superfamily enzymes R Hirmondo, A Lopata, EV Suranyi, BG Vertessy, J Toth Scientific reports 7 (1), 6043, 2017 | 31 | 2017 |
Bisepoxide cross‐linked enzyme aggregates—New immobilized biocatalysts for selective biotransformations D Weiser, A Varga, K Kovács, F Nagy, A Szilágyi, BG Vértessy, C Paizs, ... ChemCatChem 6 (5), 1463-1469, 2014 | 31 | 2014 |
Investigations of homologous disaccharides by elastic incoherent neutron scattering and wavelet multiresolution analysis S Magazů, F Migliardo, BG Vertessy, MT Caccamo Chemical Physics 424, 56-61, 2013 | 31 | 2013 |
dUTPase and nucleocapsid polypeptides of the Mason-Pfizer monkey virus form a fusion protein in the virion with homotrimeric organization and low catalytic efficiency O Barabás, M Rumlová, A Erdei, V Pongrácz, I Pichová, BG Vértessy Journal of Biological Chemistry 278 (40), 38803-38812, 2003 | 31 | 2003 |
Specific characteristics of phosphofructokinase-microtubule interaction BG Vértessy, J Kovács, J Ovádi FEBS letters 379 (2), 191-195, 1996 | 31 | 1996 |
Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases E Takács, G Nagy, I Leveles, V Harmat, A Lopata, J Tóth, BG Vértessy FEBS letters 584 (14), 3047-3054, 2010 | 30 | 2010 |
Anti-calmodulin potency of indol alkaloids in in vitro systems A Molnár, K Liliom, F Orosz, BG Vértessy, J Ovádi European Journal of Pharmacology: Molecular Pharmacology 291 (2), 73-82, 1995 | 30 | 1995 |
Enzymatic degradation of poly-[(R)-3-hydroxybutyrate]: mechanism, kinetics, consequences P Polyák, E Dohovits, GN Nagy, BG Vértessy, G Vörös, B Pukánszky International journal of biological macromolecules 112, 156-162, 2018 | 29 | 2018 |
Composite aromatic boxes for enzymatic transformations of quaternary ammonium substrates GN Nagy, L Marton, A Contet, O Ozohanics, LM Ardelean, Á Révész, ... Angewandte Chemie International Edition 53 (49), 13471-13476, 2014 | 28 | 2014 |
The interaction of a new anti‐tumour drug, KAR‐2 with calmodulin F Orosz, BG Vértessy, C Salerno, C Crifo, E Capuozzo, J Ovádi British journal of pharmacology 121 (5), 955-962, 1997 | 27 | 1997 |
Unshielding multidrug resistant cancer through selective iron depletion of P-glycoprotein–expressing cells M Cserepes, D Türk, S Tóth, VFS Pape, A Gaál, M Gera, JE Szabó, ... Cancer Research 80 (4), 663-674, 2020 | 25 | 2020 |
The Fourth Wave of Biocatalysis Emerges—The 13 th International Symposium on Biocatalysis and Biotransformations L Poppe, BG Vértessy ChemBioChem 19 (4), 284-287, 2018 | 25 | 2018 |
Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation G Róna, M Borsos, JJ Ellis, AM Mehdi, M Christie, Z Környei, M Neubrandt, ... Cell cycle 13 (22), 3551-3564, 2014 | 25 | 2014 |
Molecular cloning and characterization of a thermostable esterase/lipase produced by a novel Anoxybacillus flavithermus strain L Chiş, F Hriscu, M, Bica, A, Toşa, M, Nagy, Gergely, Róna J Gen Appl Microbiol. 59 (2), 119-134, 2013 | 25 | 2013 |
Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and … O Barabas, V Nemeth, A Bodor, A Perczel, E Rosta, Z Kele, I Zagyva, ... Nucleic Acids Research 41 (22), 10542-10555, 2013 | 24 | 2013 |
Evidence-based structural model of the staphylococcal repressor protein: separation of functions into different domains K Nyíri, B Kőhegyi, A Micsonai, J Kardos, BG Vertessy PLoS One 10 (9), e0139086, 2015 | 23 | 2015 |
Study of solvent–protein coupling effects by neutron scattering B Varga, F Migliardo, E Takacs, B Vertessy, S Magazů, MTF Telling Journal of biological physics 36, 207-220, 2010 | 23 | 2010 |
Structural model of human dUTPase in complex with a novel proteinaceous inhibitor K Nyíri, HDT Mertens, B Tihanyi, GN Nagy, B Kőhegyi, J Matejka, ... Scientific Reports 8 (1), 4326, 2018 | 22 | 2018 |
The nucleotidohydrolases DCTPP1 and dUTPase are involved in the cellular response to decitabine CE Requena, G Pérez-Moreno, A Horváth, BG Vértessy, LM Ruiz-Pérez, ... Biochemical Journal 473 (17), 2635-2643, 2016 | 22 | 2016 |
Expression and purification of recombinant phenylalanine ammonia-lyase from Petroselinum crispum NA Dima, A Filip, LC Bencze, M Olah, P Satorhelyi, BG Vértessy, L Poppe Studia Universitatis Babes-Bolyai Chemia 61 (2), 21-34, 2016 | 22 | 2016 |
Dissociation of calmodulin-target peptide complexes by the lipid mediator sphingosylphosphorylcholine: implications in calcium signaling E Kovacs, J Tóth, BG Vértessy, K Liliom Journal of biological chemistry 285 (3), 1799-1808, 2010 | 22 | 2010 |
Multidimensional NMR identifies the conformational shift essential for catalytic competence in the 60-kDa Drosophila melanogaster dUTPase trimer Z Dubrovay, Z Gáspári, E Hunyadi-Gulyás, KF Medzihradszky, A Perczel, ... Journal of Biological Chemistry 279 (17), 17945-17950, 2004 | 22 | 2004 |
Modulation of the interaction between aldolase and glycerol-phosphate dehydrogenase by fructose phosphates BG Vértessy, F Orosz, J Ovádi Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1991 | 22 | 1991 |
Evolutionary and mechanistic insights into substrate and product accommodation of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum GN Nagy, L Marton, B Krámos, J Oláh, Á Révész, K Vékey, F Delsuc, ... The FEBS journal 280 (13), 3132-3148, 2013 | 21 | 2013 |
Amphiphilic nature of new antitubercular drug candidates and their interaction with lipid monolayer K Hill, CB Pénzes, BG Vértessy, Z Szabadka, V Grolmusz, É Kiss Colloids for Nano-and Biotechnology, 87-92, 2008 | 20 | 2008 |
Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines GA Rácz, N Nagy, J Tóvári, Á Apáti, BG Vértessy Scientific Reports 11 (1), 19459, 2021 | 19 | 2021 |
Substrate tunnel engineering aided by X-ray crystallography and functional dynamics swaps the function of MIO-enzymes Z Bata, Z Molnar, E Madaras, B Molnar, E Santa-Bell, A Varga, I Leveles, ... Acs Catalysis 11 (8), 4538-4549, 2021 | 19 | 2021 |
CRISPR/Cas9-mediated knock-out of dUTPase in mice leads to early embryonic lethality HL Pálinkás, GA Rácz, Z Gál, OI Hoffmann, G Tihanyi, G Róna, E Gócza, ... Biomolecules 9 (4), 136, 2019 | 19 | 2019 |
Nuclear localization signal-dependent and-independent movements of Drosophila melanogaster dUTPase isoforms during nuclear cleavage V Muha, I Zagyva, Z Venkei, J Szabad, BG Vértessy Biochemical and biophysical research communications 381 (2), 271-275, 2009 | 19 | 2009 |
Assessment of tractable cysteines for covalent targeting by screening covalent fragments L Petri, P Ábrányi‐Balogh, I Tímea, G Pálfy, A Perczel, D Knez, M Hrast, ... ChemBioChem 22 (4), 743-753, 2021 | 18 | 2021 |
Structure-based inhibitor design of mutant RAS proteins—a paradigm shift K Nyíri, G Koppány, BG Vértessy Cancer and Metastasis Reviews 39, 1091-1105, 2020 | 18 | 2020 |
Identification of extracellular segments by mass spectrometry improves topology prediction of transmembrane proteins T Langó, G Róna, É Hunyadi-Gulyás, L Turiák, J Varga, L Dobson, ... Scientific Reports 7 (1), 42610, 2017 | 17 | 2017 |
Discovery of novel MDR-Mycobacterium tuberculosis inhibitor by new FRIGATE computational screen C Scheich, Z Szabadka, B Vértessy, V Pütter, V Grolmusz, M Schade PloS one 6 (12), e28428, 2011 | 17 | 2011 |
Structural insights into the tyrosine phosphorylation–mediated inhibition of SH3 domain–ligand interactions B Merő, L Radnai, G Gógl, O Tőke, I Leveles, K Koprivanacz, B Szeder, ... Journal of Biological Chemistry 294 (12), 4608-4620, 2019 | 16 | 2019 |