Követés
István Gyertyán
István Gyertyán
group leader, MTA-SE NAP B Cognitive Translational Behavioural Pharmacology Group, Semmelweis University
E-mail megerősítve itt: med.semmelweis-univ.hu
Cím
Hivatkozott rá
Hivatkozott rá
Év
Cariprazine (RGH-188), a dopamine D3 receptor-preferring, D3/D2 dopamine receptor antagonist–partial agonist antipsychotic candidate: in vitro and neurochemical profile
B Kiss, A Horváth, Z Némethy, É Schmidt, I Laszlovszky, G Bugovics, ...
Journal of Pharmacology and Experimental Therapeutics 333 (1), 328-340, 2010
3912010
Dopamine D3 receptor antagonists improve the learning performance in memory-impaired rats
J Laszy, I Laszlovszky, I Gyertyán
Psychopharmacology 179, 567-575, 2005
1652005
Analysis of the marble burying response: marbles serve to measure digging rather than evoke burying
I Gyertyan
Behavioural pharmacology 6 (1), 24-31, 1995
1591995
mCPP-induced anxiety in the light-dark box in rats–a new method for screening anxiolytic activity
A Bilkei-Gorzo, I Gyertyan, G Levay
Psychopharmacology 136, 291-298, 1998
1561998
Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents
I Gyertyán, B Kiss, K Sághy, J Laszy, G Szabó, T Szabados, LI Gémesi, ...
Neurochemistry international 59 (6), 925-935, 2011
1552011
Cariprazine, a dopamine D3-receptor-preferring partial agonist, blocks phencyclidine-induced impairments of working memory, attention set-shifting, and …
R Zimnisky, G Chang, I Gyertyán, B Kiss, N Adham, C Schmauss
Psychopharmacology 226, 91-100, 2013
1252013
Effects of cariprazine, a novel antipsychotic, on cognitive deficit and negative symptoms in a rodent model of schizophrenia symptomatology
JC Neill, B Grayson, B Kiss, I Gyertyán, P Ferguson, N Adham
European Neuropsychopharmacology 26 (1), 3-14, 2016
1112016
Discovery of cariprazine (RGH-188): a novel antipsychotic acting on dopamine D3/D2 receptors
É Ágai-Csongor, G Domány, K Nógrádi, J Galambos, I Vágó, GM Keserű, ...
Bioorganic & medicinal chemistry letters 22 (10), 3437-3440, 2012
992012
Cariprazine Exhibits Anxiolytic and Dopamine D3 Receptor-Dependent Antidepressant Effects in the Chronic Stress Model
V Duric, M Banasr, T Franklin, A Lepack, N Adham, B Kiss, I Gyertyán, ...
International Journal of neuropsychopharmacology 20 (10), 788-796, 2017
982017
Dopamine D3 as well as D2 receptor ligands attenuate the cue-induced cocaine-seeking in a relapse model in rats
K Gál, I Gyertyán
Drug and alcohol dependence 81 (1), 63-70, 2006
882006
Attenuation of anhedonia by cariprazine in the chronic mild stress model of depression
M Papp, P Gruca, M Lason-Tyburkiewicz, N Adham, B Kiss, I Gyertyán
Behavioural Pharmacology 25 (5 and 6), 567-574, 2014
812014
Critical evaluation of the use of dogs in biomedical research and testing in Europe
N Hasiwa, J Bailey, P Clausing, M Daneshian, S Farkas, I Gyertyán, ...
762011
Critical evaluation of the use of dogs in biomedical research and testing in Europe
N Hasiwa, J Bailey, P Clausing, M Daneshian, S Farkas, I Gyertyán, ...
762011
Critical evaluation of the use of dogs in biomedical research and testing in Europe
N Hasiwa, J Bailey, P Clausing, M Daneshian, S Farkas, I Gyertyán, ...
762011
The dopamine D3-preferring D2/D3 dopamine receptor partial agonist, cariprazine, reverses behavioural changes in a rat neurodevelopmental model for schizophrenia
DJG Watson, MV King, I Gyertyán, B Kiss, N Adham, KCF Fone
European Neuropsychopharmacology 26 (2), 208-224, 2016
712016
Dopamine D3 receptor ligands show place conditioning effect but do not influence cocaine-induced place preference
I Gyertyán, K Gál
Neuroreport 14 (1), 93-98, 2003
702003
Classification and reporting of severity experienced by animals used in scientific procedures: FELASA/ECLAM/ESLAV Working Group report
D Smith, D Anderson, AD Degryse, C Bol, A Criado, A Ferrara, NH Franco, ...
Laboratory animals 52 (1_suppl), 5-57, 2018
682018
Targeting the dopamine D3 receptor cannot influence continuous reinforcement cocaine self-administration in rats
K Gál, I Gyertyán
Brain research bulletin 61 (6), 595-601, 2003
642003
Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural …
I Gyertyán, K Sághy, J Laszy, O Elekes, R Kedves, LI Gémesi, G Pásztor, ...
Naunyn-Schmiedeberg's archives of pharmacology 378, 529-539, 2008
592008
Occupancy of dopamine D2 and D3 and serotonin 5-HT1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain …
N Seneca, SJ Finnema, I Laszlovszky, B Kiss, A Horváth, G Pásztor, ...
Psychopharmacology 218, 579-587, 2011
562011
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