Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency RB Kapust, J Tözsér, JD Fox, DE Anderson, S Cherry, TD Copeland, ... Protein engineering 14 (12), 993-1000, 2001 | 1046 | 2001 |
The P1′ specificity of tobacco etch virus protease RB Kapust, J Tözsér, TD Copeland, DS Waugh Biochemical and biophysical research communications 294 (5), 949-955, 2002 | 490 | 2002 |
Research applications of proteolytic enzymes in molecular biology JA Mótyán, F Tóth, J Tőzsér Biomolecules 3 (4), 923-942, 2013 | 340 | 2013 |
Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages MM Budai, A Varga, S Milesz, J Tőzsér, S Benkő Molecular immunology 56 (4), 471-479, 2013 | 206 | 2013 |
Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease T Sperka, J Pitlik, P Bagossi, J Tözsér Bioorganic & medicinal chemistry letters 15 (12), 3086-3090, 2005 | 199 | 2005 |
Comparison of the HIV-1 and HIV-2 proteinases using oligopeptide substrates representing cleavage sites in Gag and Gag-Pol polyproteins J Tözsér, I Bláha, TD Copeland, EM Wondrak, S Oroszlan FEBS letters 281 (1-2), 77-80, 1991 | 196 | 1991 |
Efficient site-specific processing of fusion proteins by tobacco vein mottling virus protease in vivo and in vitro S Nallamsetty, RB Kapust, J Tözsér, S Cherry, JE Tropea, TD Copeland, ... Protein expression and purification 38 (1), 108-115, 2004 | 184 | 2004 |
Changes in the chemical barrier composition of tears in Alzheimer’s disease reveal potential tear diagnostic biomarkers G Kalló, M Emri, Z Varga, B Ujhelyi, J Tőzsér, A Csutak, É Csősz PloS one 11 (6), e0158000, 2016 | 160 | 2016 |
Natural Compounds as Regulators of NLRP3 Inflammasome‐Mediated IL‐1β Production J Tőzsér, S Benkő Mediators of Inflammation 2016 (1), 5460302, 2016 | 147 | 2016 |
Quantitative analysis of proteins in the tear fluid of patients with diabetic retinopathy É Csősz, P Boross, A Csutak, A Berta, F Tóth, S Póliska, Z Török, J Tőzsér Journal of proteomics 75 (7), 2196-2204, 2012 | 145 | 2012 |
Kinetic and modeling studies of S3-S3'subsites of HIV proteinases J Tozser, IT Weber, A Gustchina, I Blaha, TD Copeland, JM Louis, ... Biochemistry 31 (20), 4793-4800, 1992 | 124 | 1992 |
Folded monomer of HIV-1 protease R Ishima, R Ghirlando, J Tözsér, AM Gronenborn, DA Torchia, JM Louis Journal of Biological Chemistry 276 (52), 49110-49116, 2001 | 119 | 2001 |
Atomic resolution crystal structures of HIV‐1 protease and mutants V82A and I84V with saquinavir Y Tie, AY Kovalevsky, P Boross, YF Wang, AK Ghosh, J Tozser, ... Proteins: Structure, Function, and Bioinformatics 67 (1), 232-242, 2007 | 118 | 2007 |
Analysis of the efficacy of HIV protease inhibitors against SARS-CoV-2′ s main protease M Mahdi, JA Mótyán, ZI Szojka, M Golda, M Miczi, J Tőzsér Virology journal 17, 1-8, 2020 | 105 | 2020 |
Substitution of proline with pipecolic acid at the scissile bond converts a peptide substrate of HIV proteinase into a selective inhibitor TD Copeland, EM Wondrak, J Tozser, MM Roberts, S Oroszlan Biochemical and biophysical research communications 169 (1), 310-314, 1990 | 104 | 1990 |
Effect of sequence polymorphism and drug resistance on two HIV‐1 Gag processing sites A Feher, IT Weber, P Bagossi, P Boross, B Mahalingam, JM Louis, ... European journal of biochemistry 269 (16), 4114-4120, 2002 | 103 | 2002 |
Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S F Liu, PI Boross, YF Wang, J Tozser, JM Louis, RW Harrison, IT Weber Journal of molecular biology 354 (4), 789-800, 2005 | 102 | 2005 |
HIV-I protease: Maturation, enzyme specificity, and drug resistance JM Louis, IT Webert, J Tözsér, GM Clore, AM Gronenborn Advances in pharmacology 49, 111-146, 2000 | 100 | 2000 |
Quantitative body fluid proteomics in medicine—A focus on minimal invasiveness É Csősz, G Kalló, B Márkus, E Deák, A Csutak, J Tőzsér Journal of proteomics 153, 30-43, 2017 | 97 | 2017 |
Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 Å resolution crystal structures of HIV‐1 protease mutants with substrate analogs Y Tie, PI Boross, YF Wang, L Gaddis, F Liu, X Chen, J Tozser, ... The FEBS journal 272 (20), 5265-5277, 2005 | 94 | 2005 |