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Aditya Ambade, PhD
Aditya Ambade, PhD
Charles River Labs, Shrewsbury, MA, United States
Verified email at crl.com
Title
Cited by
Cited by
Year
An essential role for monocyte chemoattractant protein‐1 in alcoholic liver injury: Regulation of proinflammatory cytokines and hepatic steatosis in mice
P Mandrekar, A Ambade, A Lim, G Szabo, D Catalano
Hepatology 54 (6), 2185-2197, 2011
3142011
Oxidative stress and inflammation: essential partners in alcoholic liver disease
A Ambade, P Mandrekar
International journal of hepatology 2012, 2012
2452012
Cutting edge: Necrosis activates the NLRP3 inflammasome
H Li, A Ambade, F Re
The Journal of Immunology 183 (3), 1528-1532, 2009
1662009
Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol‐Induced Liver Damage, Steatosis, and Inflammation in Mice
A Ambade, P Lowe, K Kodys, D Catalano, B Gyongyosi, Y Cho, ...
Hepatology 69 (3), 1105-1121, 2019
1642019
MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and Patients From Ethanol-Induced Liver Disease
A Satishchandran, A Ambade, S Rao, YC Hsueh, A Iracheta-Vellve, ...
Gastroenterology 154 (1), 238-252. e7, 2018
1392018
Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high …
M Ganz, TN Bukong, T Csak, B Saha, JK Park, A Ambade, K Kodys, ...
Journal of Translational Medicine 13, 193, 2015
1352015
Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice
PP Lowe, B Gyongyosi, A Satishchandran, A Iracheta-Vellve, A Ambade, ...
PLoS One 12 (3), e0174544, 2017
1182017
Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use
TN Bukong, Y Cho, A Iracheta-Vellve, B Saha, P Lowe, A Adejumo, I Furi, ...
Journal of hepatology 69 (5), 1145-1154, 2018
1152018
Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression
PP Lowe, B Gyongyosi, A Satishchandran, A Iracheta-Vellve, Y Cho, ...
Journal of neuroinflammation 15, 1-12, 2018
1042018
Macrophage‐Specific Hypoxia‐Inducible Factor‐1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis
X Wang, M de Carvalho Ribeiro, A Iracheta‐Vellve, P Lowe, A Ambade, ...
Hepatology 69 (2), 545-563, 2019
942019
Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide‐induced liver injury in mice
A Ambade, D Catalano, A Lim, P Mandrekar
Hepatology 55 (5), 1585-1595, 2012
942012
Hepatocellular carcinoma is accelerated by NASH involving M2 macrophage polarization mediated by hif-1 α induced IL-10
A Ambade, A Satishchandran, B Saha, B Gyongyosi, P Lowe, K Kodys, ...
OncoImmunology 5 (10), e1221557, 2016
912016
FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice
A Iracheta‐Vellve, CD Calenda, J Petrasek, A Ambade, K Kodys, ...
Hepatology communications 2 (11), 1379-1391, 2018
872018
Alcohol‐induced miR‐155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease
S Bala, T Csak, K Kodys, D Catalano, A Ambade, I Furi, P Lowe, Y Cho, ...
Journal of leukocyte biology 102 (2), 487-498, 2017
852017
Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1α activation
A Ambade, A Satishchandran, G Szabo
Scientific reports 6 (1), 21340, 2016
802016
Moderate Alcohol Induces Stress Proteins HSF1 and hsp70 and Inhibits Proinflammatory Cytokines Resulting in Endotoxin Tolerance
S Muralidharan, A Ambade, MA Fulham, J Deshpande, D Catalano, ...
The Journal of Immunology 193 (4), 1975-1987, 2014
792014
Pharmacological Inhibition of Heat Shock Protein 90 Alleviates Steatosis and Macrophage Activation in Murine Acute and Chronic Alcoholic Liver Injury
A Ambade, D Catalano, A Lim, A Kopoyan, SA Shaffer, P Mandrekar
Journal of Hepatology 61 (4), 903-11, 2014
77*2014
Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease
TN Bukong, A Iracheta‐Vellve, B Saha, A Ambade, A Satishchandran, ...
Hepatology 64 (4), 1057-1071, 2016
702016
Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease
A Ambade, A Satishchandran, B Gyongyosi, P Lowe, G Szabo
World Journal of Gastroenterology 22 (16), 4091, 2016
512016
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations
PP Lowe, C Morel, A Ambade, A Iracheta-Vellve, E Kwiatkowski, ...
Journal of neuroinflammation 17, 1-18, 2020
462020
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